- PDB-3uo1: Structure of a monoclonal antibody complexed with its MHC-I antigen -
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基本情報
登録情報
データベース: PDB / ID: 3uo1
タイトル
Structure of a monoclonal antibody complexed with its MHC-I antigen
要素
ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 H CHAIN
ANTI-MHC-I MONOCLONAL ANTIBODY, 64-3-7 L CHAIN
H-2 class I histocompatibility antigen, L-D alpha chain
キーワード
IMMUNE SYSTEM / IG-FOLD / 3 / 10-HELIX
機能・相同性
機能・相同性情報
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent / antigen processing and presentation of endogenous peptide antigen via MHC class Ib / lumenal side of endoplasmic reticulum membrane / MHC class I protein complex / defense response / positive regulation of T cell mediated cytotoxicity / phagocytic vesicle membrane / peptide antigen binding / immune response / external side of plasma membrane ...antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent / antigen processing and presentation of endogenous peptide antigen via MHC class Ib / lumenal side of endoplasmic reticulum membrane / MHC class I protein complex / defense response / positive regulation of T cell mediated cytotoxicity / phagocytic vesicle membrane / peptide antigen binding / immune response / external side of plasma membrane / signaling receptor binding / extracellular space / metal ion binding 類似検索 - 分子機能
MHC class I, alpha chain, C-terminal / MHC_I C-terminus / MHC class I alpha chain, alpha1 alpha2 domains / Class I Histocompatibility antigen, domains alpha 1 and 2 / Immunoglobulin V-Type / MHC class I-like antigen recognition-like / MHC class I-like antigen recognition-like superfamily / Immunoglobulin V-set domain / MHC classes I/II-like antigen recognition protein / Immunoglobulin V-set domain ...MHC class I, alpha chain, C-terminal / MHC_I C-terminus / MHC class I alpha chain, alpha1 alpha2 domains / Class I Histocompatibility antigen, domains alpha 1 and 2 / Immunoglobulin V-Type / MHC class I-like antigen recognition-like / MHC class I-like antigen recognition-like superfamily / Immunoglobulin V-set domain / MHC classes I/II-like antigen recognition protein / Immunoglobulin V-set domain / Immunoglobulin/major histocompatibility complex, conserved site / Immunoglobulins and major histocompatibility complex proteins signature. / Immunoglobulin subtype / Immunoglobulin / Immunoglobulin C-Type / Immunoglobulin C1-set / Immunoglobulin C1-set domain / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulins / Immunoglobulin-like fold / Immunoglobulin-like / Sandwich / Mainly Beta 類似検索 - ドメイン・相同性
If kappa light chain / H-2 class I histocompatibility antigen, L-D alpha chain 類似検索 - 構成要素
温度: 277 K / 手法: 蒸気拡散法, ハンギングドロップ法 / pH: 8.5 詳細: antibody at 6.8 mg/ml mixed with equimolar peptide and then 1:1 with 0.1 M LiSO4, 0.1 M TRIS, 30% w/v PEG 3000, pH 8.5, VAPOR DIFFUSION, HANGING DROP, temperature 277.0K