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Open data
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Basic information
Entry | Database: PDB / ID: 2otu | ||||||
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Title | Crystal structure of Fv polyglutamine complex | ||||||
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![]() | IMMUNE SYSTEM / Antibody Fv polyglutamine complex | ||||||
Function / homology | ![]() Immunoglobulin V-Type / Immunoglobulin V-set domain / Immunoglobulin V-set domain / Immunoglobulin subtype / Immunoglobulin / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulins / Immunoglobulin-like fold ...Immunoglobulin V-Type / Immunoglobulin V-set domain / Immunoglobulin V-set domain / Immunoglobulin subtype / Immunoglobulin / Ig-like domain profile. / Immunoglobulin-like domain / Immunoglobulin-like domain superfamily / Immunoglobulins / Immunoglobulin-like fold / Immunoglobulin-like / Sandwich / Mainly Beta Similarity search - Domain/homology | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Li, P. | ||||||
![]() | ![]() Title: Implications of the structure of a poly-Gln/anti-poly-Gln complex for disease progression and therapy Authors: Li, P. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 216.4 KB | Display | ![]() |
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PDB format | ![]() | 173.7 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 512.1 KB | Display | ![]() |
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Full document | ![]() | 528.1 KB | Display | |
Data in XML | ![]() | 46.8 KB | Display | |
Data in CIF | ![]() | 67.9 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 2otwC ![]() 2gsgS S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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2 | ![]()
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3 | ![]()
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4 | ![]()
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Unit cell |
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Components
#1: Antibody | Mass: 12460.883 Da / Num. of mol.: 4 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() #2: Antibody | Mass: 13330.936 Da / Num. of mol.: 4 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() #3: Protein/peptide | Mass: 1356.355 Da / Num. of mol.: 4 / Source method: obtained synthetically / Details: synthetic peptide #4: Water | ChemComp-HOH / | |
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-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.48 Å3/Da / Density % sol: 50.33 % |
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Crystal grow | Temperature: 298 K / Method: evaporation / pH: 6 Details: 0.1 M sodium citrate, 0.2 M NH4Ac, 27.5% PEG 4000, pH 6.0, EVAPORATION, temperature 298K |
-Data collection
Diffraction | Mean temperature: 173 K |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: ADSC QUANTUM 315 / Detector: CCD / Date: Jan 1, 2006 / Details: Si(111) |
Radiation | Monochromator: Si (111) / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 1 Å / Relative weight: 1 |
Reflection | Resolution: 1.68→41 Å / Num. all: 119617 / Num. obs: 116627 / % possible obs: 97.5 % / Redundancy: 4.4 % / Rmerge(I) obs: 0.046 / Rsym value: 4.3 / Net I/σ(I): 34.3 |
Reflection shell | Resolution: 1.68→1.74 Å / Redundancy: 3.5 % / Rmerge(I) obs: 0.258 / Mean I/σ(I) obs: 3.4 / Num. unique all: 10848 / Rsym value: 25.8 / % possible all: 91.1 |
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Processing
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Refinement | Method to determine structure: ![]() Starting model: PDB entry 2GSG Resolution: 1.68→41 Å / Isotropic thermal model: isotropic / Cross valid method: THROUGHOUT / σ(F): 0 / σ(I): 0 / Stereochemistry target values: Engh & Huber
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Refinement step | Cycle: LAST / Resolution: 1.68→41 Å
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Refine LS restraints |
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LS refinement shell | Highest resolution: 1.68 Å
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