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- PDB-1a7o: FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) R... -
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Open data
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Basic information
Entry | Database: PDB / ID: 1a7o | ||||||
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Title | FV FRAGMENT OF MOUSE MONOCLONAL ANTIBODY D1.3 (BALB/C, IGG1, K) R96L DELETION MUTANT ON VARIANT FOR CHAIN L GLU81->ASP AND CHAIN H LEU312->VAL | ||||||
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![]() | IMMUNOGLOBULIN / DELETION MUTANT | ||||||
Function / homology | ![]() immunoglobulin complex / immunoglobulin mediated immune response / antigen binding / adaptive immune response / blood microparticle / immune response / extracellular space Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() | ||||||
![]() | Marks, C. / Henrick, K. / Winter, G. | ||||||
![]() | ![]() Title: X-Ray Structures of D1.3 Fv Mutants Authors: Marks, C. / Henrick, K. / Winter, G. #1: ![]() Title: Bound Water Molecules and Conformational Stabilization Help Mediate an Antigen-Antibody Association Authors: Bhat, T.N. / Bentley, G.A. / Boulot, G. / Greene, M.I. / Tello, D. / Dall'Acqua, W. / Souchon, H. / Schwarz, F.P. / Mariuzza, R.A. / Poljak, R.J. #2: ![]() Title: Small Rearrangements in Structures of Fv and Fab Fragments of Antibody D1.3 On Antigen Binding Authors: Bhat, T.N. / Bentley, G.A. / Fischmann, T.O. / Boulot, G. / Poljak, R.J. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 55.8 KB | Display | ![]() |
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PDB format | ![]() | 42 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 422.5 KB | Display | ![]() |
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Full document | ![]() | 432.1 KB | Display | |
Data in XML | ![]() | 13 KB | Display | |
Data in CIF | ![]() | 17.6 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 1a7nC ![]() 1a7pC ![]() 1a7qC ![]() 1a7rC ![]() 1vfaS S: Starting model for refinement C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Components
#1: Antibody | Mass: 11529.757 Da / Num. of mol.: 1 / Fragment: FV FRAGMENT / Mutation: DEL(R96), E81D Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() |
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#2: Antibody | Mass: 12843.249 Da / Num. of mol.: 1 / Fragment: FV FRAGMENT / Mutation: L312V Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() |
#3: Water | ChemComp-HOH / |
Compound details | THE ANTIBODY IS SECRETED INTO PERIPLASMIC SPACE. VH AND VL DOMAINS ARE COVALENTLY LINKED AND THEY ...THE ANTIBODY IS SECRETED INTO PERIPLASMI |
-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.38 Å3/Da / Density % sol: 48.2 % |
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-Data collection
Diffraction | Mean temperature: 269 K |
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Diffraction source | Wavelength: 1.5418 |
Detector | Type: MARRESEARCH / Detector: IMAGE PLATE / Date: Jun 1, 1992 |
Radiation | Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 1.5418 Å / Relative weight: 1 |
Reflection | Resolution: 2→17.23 Å / Num. obs: 15419 / % possible obs: 95.1 % / Observed criterion σ(I): 0 / Redundancy: 7 % / Biso Wilson estimate: 27.64 Å2 / Rmerge(I) obs: 0.084 |
Reflection shell | Resolution: 2→2.11 Å / Redundancy: 5.4 % / Rmerge(I) obs: 0.329 / % possible all: 86.3 |
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Processing
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Refinement | Method to determine structure: ![]() Starting model: PDB ENTRY 1VFA Resolution: 2→6 Å / σ(F): 0 /
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Displacement parameters | Biso mean: 26.87 Å2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Resolution: 2→6 Å
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Refine LS restraints |
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