- PDB-2jjw: Structure of human signal regulatory protein (sirp) gamma -
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IDまたはキーワード:
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基本情報
登録情報
データベース: PDB / ID: 2jjw
タイトル
Structure of human signal regulatory protein (sirp) gamma
要素
SIGNAL REGULATORY PROTEIN GAMMA
キーワード
CELL ADHESION / IMMUNOGLOBULIN DOMAIN / IMMUNOGLOBULIN SUPERFAMILY / SIRP / SIRPG / MEMBRANE / GLYCOPROTEIN / SIGNAL REGULATORY PROTEIN GAMMA / TRANSMEMBRANE / PAIRED RECEPTOR / ALTERNATIVE SPLICING
機能・相同性
機能・相同性情報
positive regulation of cell-cell adhesion / Signal regulatory protein family interactions / positive regulation of phagocytosis / Cell surface interactions at the vascular wall / positive regulation of T cell activation / cell-cell signaling / cell adhesion / intracellular signal transduction / negative regulation of cell population proliferation / positive regulation of cell population proliferation ...positive regulation of cell-cell adhesion / Signal regulatory protein family interactions / positive regulation of phagocytosis / Cell surface interactions at the vascular wall / positive regulation of T cell activation / cell-cell signaling / cell adhesion / intracellular signal transduction / negative regulation of cell population proliferation / positive regulation of cell population proliferation / membrane / plasma membrane 類似検索 - 分子機能
SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN ... SHEET THE SHEET STRUCTURE OF THIS MOLECULE IS BIFURCATED. IN ORDER TO REPRESENT THIS FEATURE IN THE SHEET RECORDS BELOW, TWO SHEETS ARE DEFINED.
RESIDUE NUMBERING IS FOR THE MATURE PROTEIN (LACKING N- TERMINAL 28 AMINO ACID SIGNAL SEQUENCE). C- ...RESIDUE NUMBERING IS FOR THE MATURE PROTEIN (LACKING N- TERMINAL 28 AMINO ACID SIGNAL SEQUENCE). C-TERMINAL PURIFICATION TAG (TRHHHHHH) IS ADDED.
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実験情報
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実験
実験
手法: X線回折 / 使用した結晶の数: 1
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試料調製
結晶
マシュー密度: 2.32 Å3/Da / 溶媒含有率: 47.1 % / 解説: NONE
結晶化
pH: 6.5 詳細: 300 NL 11.5 MG/ML SIRP GAMMA PLUS 50 NL RESERVOIR (2.0 M AMMONIUM SULPHATE, 0.1 M BIS-TRIS PH 6.5) EQUILIBRATED AGAINST 95 UL OF RESERVOIR AT 20.5 C.
解像度: 1.7→38.21 Å / Cor.coef. Fo:Fc: 0.95 / Cor.coef. Fo:Fc free: 0.94 / SU B: 6.453 / SU ML: 0.106 / 交差検証法: THROUGHOUT / ESU R: 0.122 / ESU R Free: 0.122 / 立体化学のターゲット値: MAXIMUM LIKELIHOOD 詳細: HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS. B VALUES INCLUDE TLS CONTRIBUTIONS.
Rfactor
反射数
%反射
Selection details
Rfree
0.267
724
4.9 %
RANDOM
Rwork
0.228
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obs
0.23
13927
95.2 %
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溶媒の処理
イオンプローブ半径: 0.8 Å / 減衰半径: 0.8 Å / VDWプローブ半径: 1.2 Å / 溶媒モデル: MASK