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Structure paper

TitlePaired receptor specificity explained by structures of signal regulatory proteins alone and complexed with CD47.
Journal, issue, pagesMol. Cell, Vol. 31, Page 266-277, Year 2008
Publish dateApr 22, 2008 (structure data deposition date)
AuthorsHatherley, D. / Graham, S.C. / Turner, J. / Harlos, K. / Stuart, D.I. / Barclay, A.N.
External linksMol. Cell / PubMed:18657508
MethodsX-ray diffraction
Resolution1.19 - 2.3 Å
Structure data

PDB-2jjs:
Structure of human CD47 in complex with human signal regulatory protein (SIRP) alpha
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-2jjt:
Structure of human CD47 in complex with human signal regulatory protein (SIRP) alpha
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-2jju:
Structure of human signal regulatory protein (sirp) beta
Method: X-RAY DIFFRACTION / Resolution: 1.19 Å

PDB-2jjv:
Structure of human signal regulatory protein (sirp) beta(2)
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-2jjw:
Structure of human signal regulatory protein (sirp) gamma
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-2vsc:
Structure of the immunoglobulin-superfamily ectodomain of human CD47
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-IOD:
IODIDE ION

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsCELL ADHESION / SIGNAL REGULATORY PROTEIN ALPHA / IMMUNOGLOBULIN SUPERFAMILY / TRANSMEMBRANE / PHOSPHOPROTEIN / PAIRED RECEPTOR / POLYMORPHISM / GLYCOPROTEIN / PYRROLIDONE CARBOXYLIC ACID / ALTERNATIVE SPLICING / IMMUNOGLOBULIN DOMAIN / SIRP / CD47 / SIRPA / MEMBRANE / SH3-BINDING / IMMUNE SYSTEM / SIGNAL REGULATORY PROTEIN BETA / SIRPB1 / SIRPB2 / SIRPG / SIGNAL REGULATORY PROTEIN GAMMA / SIGNAL REGULATORY PROTEIN

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