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Open data
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Basic information
Entry | Database: PDB / ID: 2cxq | ||||||
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Title | Crystal structure of mouse AMF / S6P complex | ||||||
![]() | Glucose-6-phosphate isomerase | ||||||
![]() | ISOMERASE | ||||||
Function / homology | ![]() glycolytic process through glucose-6-phosphate / Glycolysis / Gluconeogenesis / TP53 Regulates Metabolic Genes / glucose-6-phosphate isomerase / glucose-6-phosphate isomerase activity / glucose 6-phosphate metabolic process / carbohydrate derivative binding / fructose 6-phosphate metabolic process / canonical glycolysis ...glycolytic process through glucose-6-phosphate / Glycolysis / Gluconeogenesis / TP53 Regulates Metabolic Genes / glucose-6-phosphate isomerase / glucose-6-phosphate isomerase activity / glucose 6-phosphate metabolic process / carbohydrate derivative binding / fructose 6-phosphate metabolic process / canonical glycolysis / monosaccharide binding / erythrocyte homeostasis / ciliary membrane / positive regulation of immunoglobulin production / response to testosterone / mesoderm formation / response to immobilization stress / response to cadmium ion / response to muscle stretch / Neutrophil degranulation / positive regulation of endothelial cell migration / cytokine activity / gluconeogenesis / response to progesterone / glycolytic process / growth factor activity / response to estradiol / myelin sheath / glucose homeostasis / in utero embryonic development / negative regulation of neuron apoptotic process / learning or memory / ubiquitin protein ligase binding / extracellular space / plasma membrane / cytosol Similarity search - Function | ||||||
Biological species | ![]() ![]() | ||||||
Method | ![]() ![]() ![]() | ||||||
![]() | Tanaka, N. / Haga, A. / Naba, N. / Shiraiwa, K. / Kusakabe, Y. / Hashimoto, K. / Funasaka, T. / Nagase, H. / Raz, A. / Nakamura, K.T. | ||||||
![]() | ![]() Title: Crystal structures of mouse autocrine motility factor in complex with carbohydrate phosphate inhibitors provide insight into structure-activity relationship of the inhibitors Authors: Tanaka, N. / Haga, A. / Naba, N. / Shiraiwa, K. / Kusakabe, Y. / Hashimoto, K. / Funasaka, T. / Nagase, H. / Raz, A. / Nakamura, K.T. | ||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 252 KB | Display | ![]() |
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PDB format | ![]() | 199.1 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 451.4 KB | Display | ![]() |
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Full document | ![]() | 456.9 KB | Display | |
Data in XML | ![]() | 21.6 KB | Display | |
Data in CIF | ![]() | 39.3 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 2cvpC ![]() 2cxnC ![]() 2cxoC ![]() 2cxpC ![]() 2cxrC ![]() 2cxsC ![]() 2cxtC ![]() 2cxuC C: citing same article ( |
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Similar structure data |
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Links
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Assembly
Deposited unit | ![]()
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Unit cell |
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Components
#1: Protein | Mass: 62693.582 Da / Num. of mol.: 2 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() ![]() #2: Sugar | #3: Chemical | ChemComp-GOL / #4: Water | ChemComp-HOH / | |
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-Experimental details
-Experiment
Experiment | Method: ![]() |
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Sample preparation
Crystal | Density Matthews: 2.32 Å3/Da / Density % sol: 47 % |
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Crystal grow | Temperature: 293 K / Method: vapor diffusion, hanging drop / pH: 7.5 Details: Cacodylate, PEG8000, NaAcetate, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 293K |
-Data collection
Diffraction | Mean temperature: 100 K |
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Diffraction source | Source: ![]() ![]() ![]() |
Detector | Type: ADSC QUANTUM 4 / Detector: CCD |
Radiation | Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray |
Radiation wavelength | Wavelength: 1 Å / Relative weight: 1 |
Reflection | Resolution: 1.5→40 Å / Num. obs: 178728 / % possible obs: 99.2 % |
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Processing
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Refinement | Method to determine structure: ![]()
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Solvent computation | Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.4 Å / Solvent model: BABINET MODEL WITH MASK | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | Biso mean: 16.567 Å2
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Refinement step | Cycle: LAST / Resolution: 1.5→40 Å
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Refine LS restraints |
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LS refinement shell | Resolution: 1.502→1.541 Å / Total num. of bins used: 20 /
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