Entry | Database: PDB / ID: 2ckg |
---|
Title | The structure of SENP1 SUMO-2 co-complex suggests a structural basis for discrimination between SUMO paralogues during processing |
---|
Components | SENTRIN-SPECIFIC PROTEASE 1 |
---|
Keywords | HYDROLASE / PROTEASE / THIOL PROTEASE / NUCLEAR PROTEIN / UBL CONJUGATION PATHWAY |
---|
Function / homology | Function and homology information
SUMO-specific endopeptidase activity / SUMO is proteolytically processed / deSUMOylase activity / protein desumoylation / RHOF GTPase cycle / protein sumoylation / regulation of mRNA stability / apoptotic signaling pathway / activation of cysteine-type endopeptidase activity involved in apoptotic process / nuclear membrane ...SUMO-specific endopeptidase activity / SUMO is proteolytically processed / deSUMOylase activity / protein desumoylation / RHOF GTPase cycle / protein sumoylation / regulation of mRNA stability / apoptotic signaling pathway / activation of cysteine-type endopeptidase activity involved in apoptotic process / nuclear membrane / endopeptidase activity / Hydrolases; Acting on peptide bonds (peptidases); Cysteine endopeptidases / focal adhesion / positive regulation of transcription by RNA polymerase II / proteolysis / nucleoplasm / nucleus / cytoplasmSimilarity search - Function Adenoviral Proteinase; Chain / Adenoviral Proteinase; Chain A / Ubiquitin-like protease family profile. / Ulp1 protease family, C-terminal catalytic domain / Ulp1 protease family, C-terminal catalytic domain / Papain-like cysteine peptidase superfamily / 3-Layer(aba) Sandwich / Alpha BetaSimilarity search - Domain/homology |
---|
Biological species | HOMO SAPIENS (human) |
---|
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.45 Å |
---|
Authors | Dong, C. / Naismith, J.H. |
---|
Citation | Journal: Biochem.J. / Year: 2006 Title: The Structure of Senp1-Sumo-2 Complex Suggests a Structural Basis for Discrimination between Sumo Paralogues During Processing. Authors: Shen, L.N. / Dong, C. / Liu, H. / Naismith, J.H. / Hay, R.T. |
---|
History | Deposition | Apr 18, 2006 | Deposition site: PDBE / Processing site: PDBE |
---|
Supersession | Apr 26, 2006 | ID: 2BZP |
---|
Revision 1.0 | Apr 26, 2006 | Provider: repository / Type: Initial release |
---|
Revision 1.1 | Jul 13, 2011 | Group: Advisory / Version format compliance |
---|
Revision 1.2 | Aug 30, 2017 | Group: Data collection / Refinement description Category: diffrn_source / refine ...diffrn_source / refine / reflns / reflns_shell Item: _diffrn_source.pdbx_wavelength / _refine.ls_R_factor_R_free ..._diffrn_source.pdbx_wavelength / _refine.ls_R_factor_R_free / _refine.ls_R_factor_R_work / _reflns.pdbx_Rmerge_I_obs / _reflns_shell.Rmerge_I_obs |
---|
Revision 1.3 | Dec 13, 2023 | Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / diffrn_radiation_wavelength / pdbx_initial_refinement_model / struct_ncs_dom_lim Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _diffrn_radiation_wavelength.wavelength / _struct_ncs_dom_lim.beg_auth_comp_id / _struct_ncs_dom_lim.beg_label_asym_id / _struct_ncs_dom_lim.beg_label_comp_id / _struct_ncs_dom_lim.beg_label_seq_id / _struct_ncs_dom_lim.end_auth_comp_id / _struct_ncs_dom_lim.end_label_asym_id / _struct_ncs_dom_lim.end_label_comp_id / _struct_ncs_dom_lim.end_label_seq_id |
---|
|
---|