+Open data
-Basic information
Entry | Database: PDB / ID: 1ym7 | ||||||
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Title | G Protein-Coupled Receptor Kinase 2 (GRK2) | ||||||
Components | Beta-adrenergic receptor kinase 1 | ||||||
Keywords | TRANSFERASE / G protein / kinase / GPCR / GRK2 / Beta-ARK1 | ||||||
Function / homology | Function and homology information Calmodulin induced events / beta-adrenergic-receptor kinase / negative regulation of the force of heart contraction by chemical signal / negative regulation of relaxation of smooth muscle / Activation of SMO / beta-adrenergic receptor kinase activity / G protein-coupled receptor kinase activity / Edg-2 lysophosphatidic acid receptor binding / alpha-2A adrenergic receptor binding / negative regulation of striated muscle contraction ...Calmodulin induced events / beta-adrenergic-receptor kinase / negative regulation of the force of heart contraction by chemical signal / negative regulation of relaxation of smooth muscle / Activation of SMO / beta-adrenergic receptor kinase activity / G protein-coupled receptor kinase activity / Edg-2 lysophosphatidic acid receptor binding / alpha-2A adrenergic receptor binding / negative regulation of striated muscle contraction / desensitization of G protein-coupled receptor signaling pathway / positive regulation of protein localization to cilium / Cargo recognition for clathrin-mediated endocytosis / regulation of the force of heart contraction / G protein-coupled receptor internalization / positive regulation of smoothened signaling pathway / G alpha (s) signalling events / G alpha (q) signalling events / regulation of signal transduction / cardiac muscle contraction / cell projection / G protein-coupled receptor binding / intracellular protein transport / G protein-coupled acetylcholine receptor signaling pathway / presynapse / peptidyl-serine phosphorylation / postsynapse / protein kinase activity / G protein-coupled receptor signaling pathway / protein phosphorylation / ATP binding / membrane / plasma membrane / cytoplasm / cytosol Similarity search - Function | ||||||
Biological species | Bos taurus (cattle) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 4.5 Å | ||||||
Authors | Lodowski, D.T. / Barnhill, J.F. / Pyskadlo, R.M. / Ghirlando, R. / Sterne-Marr, R. / Tesmer, J.J.G. | ||||||
Citation | Journal: Biochemistry / Year: 2005 Title: The role of Gbetagamma and domain interfaces in the activation of G protein-coupled receptor kinase 2 Authors: Lodowski, D.T. / Barnhill, J.F. / Pyskadlo, R.M. / Ghirlando, R. / Sterne-Marr, R. / Tesmer, J.J.G. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 1ym7.cif.gz | 426.5 KB | Display | PDBx/mmCIF format |
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PDB format | pdb1ym7.ent.gz | 343 KB | Display | PDB format |
PDBx/mmJSON format | 1ym7.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 1ym7_validation.pdf.gz | 472.8 KB | Display | wwPDB validaton report |
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Full document | 1ym7_full_validation.pdf.gz | 526.3 KB | Display | |
Data in XML | 1ym7_validation.xml.gz | 73.8 KB | Display | |
Data in CIF | 1ym7_validation.cif.gz | 103.6 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/ym/1ym7 ftp://data.pdbj.org/pub/pdb/validation_reports/ym/1ym7 | HTTPS FTP |
-Related structure data
Related structure data | 1omwS S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Refine code: 1
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