[English] 日本語
![](img/lk-miru.gif)
- PDB-1dbj: MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-AN... -
+
Open data
-
Basic information
Entry | Database: PDB / ID: 1dbj | ||||||
---|---|---|---|---|---|---|---|
Title | MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY | ||||||
![]() |
| ||||||
![]() | ![]() | ||||||
Function / homology | ![]() humoral immune response mediated by circulating immunoglobulin / ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() Similarity search - Function | ||||||
Biological species | ![]() ![]() ![]() | ||||||
Method | ![]() | ||||||
![]() | Arevalo, J.H. / Wilson, I.A. | ||||||
![]() | ![]() Title: Molecular basis of crossreactivity and the limits of antibody-antigen complementarity. Authors: Arevalo, J.H. / Taussig, M.J. / Wilson, I.A. #1: ![]() Title: Structural Analysis of Antibody Specificity: Detailed Comparison of Five Fab'-Steroid Complexes Authors: Arevalo, J.H. / Hassig, C.A. / Stura, E.A. / Taussig, M.J. / Wilson, I.A. #2: ![]() Title: Three-Dimensional Structure of an Anti-Steroid Fab' and Progesterone-Fab' Complex Authors: Arevalo, J.H. / Stura, E.A. / Taussig, M.J. / Wilson, I.A. #3: ![]() Title: Analysis of an Anti-Progesterone Antibody: Variable Crystal Morphology of the Fab' and Steroid-Fab' Complexes Authors: Stura, E.A. / Arevalo, J.H. / Feinstein, A. / Heap, R.B. / Taussig, M.J. / Wilson, I.A. | ||||||
History |
|
-
Structure visualization
Structure viewer | Molecule: ![]() ![]() |
---|
-
Downloads & links
-
Download
PDBx/mmCIF format | ![]() | 97.3 KB | Display | ![]() |
---|---|---|---|---|
PDB format | ![]() | 73.7 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
---|
-Related structure data
-
Links
-
Assembly
Deposited unit | ![]()
| ||||||||
---|---|---|---|---|---|---|---|---|---|
1 |
| ||||||||
Unit cell |
| ||||||||
Atom site foot note | 1: CIS PROLINE - PRO L 8 / 2: CIS PROLINE - PRO L 95 / 3: CIS PROLINE - PRO L 141 / 4: CIS PROLINE - PRO H 149 / 5: CIS PROLINE - PRO H 151 / 6: CIS PROLINE - PRO H 202 |
-
Components
#1: Antibody | Mass: 23880.588 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() |
---|---|
#2: Antibody | Mass: 23754.656 Da / Num. of mol.: 1 Source method: isolated from a genetically manipulated source Source: (gene. exp.) ![]() ![]() ![]() |
#3: Chemical | ChemComp-AE2 / ![]() |
#4: Water | ChemComp-HOH / ![]() |
Nonpolymer details | THE AETIOCHOLANOLONE MOLECULE (AE2) IS LOCATED BETWEEN THE COMPLEMENTARITY-DETERMINING REGIONS L1, ...THE AETIOCHOLA |
-Experimental details
-Experiment
Experiment | Method: ![]() |
---|
-
Sample preparation
Crystal | Density Matthews: 3.42 Å3/Da / Density % sol: 63.99 % | ||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Crystal grow![]() | *PLUS pH: 7.4 / Method: vapor diffusion | ||||||||||||||||||||||||||||||
Components of the solutions | *PLUS
|
-Data collection
Radiation | Scattering type: x-ray |
---|---|
Radiation wavelength | Relative weight: 1 |
-
Processing
Software |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Refinement | Resolution: 2.7→6 Å / Rfactor Rwork![]() | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement step | Cycle: LAST / Resolution: 2.7→6 Å
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints |
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refinement | *PLUS Highest resolution: 2.7 Å / Lowest resolution: 6 Å / σ(F): 2 / Rfactor obs: 0.214 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Solvent computation | *PLUS | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Displacement parameters | *PLUS Biso mean: 29.3 Å2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Refine LS restraints | *PLUS Type: x_angle_d / Dev ideal: 3.9 |