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Showing 1 - 20 of 125,385 items (all data)
-Protein Engineering-Enabled Cryo-EM Investigation of Small GTPases.
J Mol Biol, Vol. 438, Issue 17, Page 169860, Year 2026
Zhengshan Hu / Unnatiben Rajeshbhai Patel / Eliezra Glasser / Akiko Koide / Shohei Koide
Methods: EM (single particle)
-Crystalline Biomaterials for Site-Specific Organization of Modified DNA
To Be Published, Slaughter, C.K. / Shields, E.T. / Magna, E.N. / Platt, A. / Snow, C.D.
Methods: X-ray diffraction
-Probing Protein-Ligand Methyl-pi Interaction Geometries through Chemical Shift Measurements of Selectively Labeled Methyl Groups.
J Med Chem, Vol. 67, Page 13187-13196, Year 2024Beier, A. / Platzer, G. / Hofurthner, T. / Ptaszek, A.L. / Lichtenecker, R.J. / Geist, L. / Fuchs, J.E. / McConnell, D.B. / Mayer, M. / Konrat, R.
Methods: X-ray diffraction
-Mechanism of lipid transfer by bridge-like protein VPS13A and the scramblase XK.
Cell, Vol. 189, Issue 16, Page 5135-55149.e6, Year 2026Bodan Hu / Daniel Álvarez / Cristian Rocha-Roa / Valentin Guyard / Dazhi Li / Yara Ahmed / Xinbo Wang / Pietro De Camilli / Stefano Vanni / Karin M Reinisch
Methods: EM (single particle)
-Cryo-EM Structure of the Human Mas Receptor Reveals N-terminal Occlusion of the Orthosteric Ligand Binding Pocket.
J Mol Biol, Vol. 438, Issue 16, Page 169844, Year 2026Shota Suzuki / Kotaro Tanaka / Kouki Nishikawa / Yoshinori Fujiyoshi
Methods: EM (single particle)
-Human TRIM21 PRYSPRY domain in complex with compound 29 (Z37)
To Be Published, Kim, Y. / Schallmayer, L. / Knapp, S. / Kraemer, A. / Structural Genomics Consortium (SGC)
Methods: X-ray diffraction
-Human TRIM21 PRYSPRY domain in complex with compound 28 (Z38)
To Be Published, Kim, Y. / Schallmayer, L. / Knapp, S. / Kraemer, A. / Structural Genomics Consortium (SGC)
Methods: X-ray diffraction
-Human sterile alpha motif domain-containing protein 9 (SAMD9), loss-of-function mutant R1562E/I1567R/E1568I
-Human TRIM21 PRYSPRY domain in complex with PRLX-93936
To Be Published, Kim, Y. / Knapp, S. / Kraemer, A. / Structural Genomics Consortium (SGC)
Methods: X-ray diffraction
-Crystallographic fragment screening of a human E3 ligase
To Be Published, Randall, G.T. / Kot, E. / Koekemoer, L. / von Delft, F.
Methods: X-ray diffraction
-Human NUP98 APD (SG P21)
To Be Published, Kim, Y. / Schallmayer, L. / Knapp, S. / Kraemer, A. / Structural Genomics Consortium (SGC)
Methods: X-ray diffraction
-Overcoming the accuracy-generalization tradeoff in docking and scoring for prospective virtual screening
Biorxiv, Year 2026Petrosyan, G. / Altunyan, V. / Ghukasyan, T. / Abramyan, T.M. / Arakelov, G. / Davtyan, A. / Aghajanyan, T. / Nakipov, I. / Navasardyan, G. / Fahradyan, A. ...Petrosyan, G. / Altunyan, V. / Ghukasyan, T. / Abramyan, T.M. / Arakelov, G. / Davtyan, A. / Aghajanyan, T. / Nakipov, I. / Navasardyan, G. / Fahradyan, A. / Tunanyan, H. / Simonyan, A. / Janczyk, P.L. / De Silva, D. / Saribekyan, H. / Tsidilkovski, L. / Arakelov, V. / Ginoyan, N. / Mnatsakanyan, H. / Ratnikov, M. / Smbatyan, K. / Papoyan, A. / Papoian, G.A.
Methods: X-ray diffraction
-Human TRIM21 PRYSPRY domain in complex with BMS-214662
To Be Published, Kim, Y. / Knapp, S. / Kraemer, A. / Structural Genomics Consortium (SGC)
Methods: X-ray diffraction
-Sterile alpha motif domain-containing protein 9, residues 623-1589
-Human sterile alpha motif domain-containing protein 9 (SAMD9), loss-of-function mutant Q514S/R515S/R522S/R553S/Q565S/R593S
-Human TRIM21 PRYSPRY domain in complex with compound 5 (Z31)
To Be Published, Kim, Y. / Schallmayer, L. / Knapp, S. / Kraemer, A. / Structural Genomics Consortium (SGC)
Methods: X-ray diffraction
-Ternary complex structure of TRIM21 (PRYSPRY) and BRD4 (BD1) bound to PROTAC 1b
To Be Published, Kim, Y. / Sokolenko, Y. / Knapp, S. / Kraemer, A. / Structural Genomics Consortium (SGC)
Methods: X-ray diffraction
-Human NUP98 APD (SG P41212)
To Be Published, Kim, Y. / Schallmayer, L. / Knapp, S. / Kraemer, A. / Structural Genomics Consortium (SGC)
Methods: X-ray diffraction
-Human TRIM21 PRYSPRY domain in complex with HGC652
To Be Published, Kim, Y. / Lucic, A. / Knapp, S. / Kraemer, A. / Structural Genomics Consortium (SGC)
Methods: X-ray diffraction
-Activation of the angiotensin II type I receptor by a nonpeptide agonist.
Proc Natl Acad Sci U S A, Vol. 123, Issue 32, Page e2602538123, Year 2026Meredith A Skiba / Jinghan Liu / Pengxiang Shen / Jihee Kim / Elizabeth Wren / Morgan S A Gilman / Dean Staus / Conor McMahon / Jeffrey S Smith / Robert J Lefkowitz ...Meredith A Skiba / Jinghan Liu / Pengxiang Shen / Jihee Kim / Elizabeth Wren / Morgan S A Gilman / Dean Staus / Conor McMahon / Jeffrey S Smith / Robert J Lefkowitz / Daniel Kahne / Laura M Wingler / Andrew C Kruse
Methods: EM (single particle)
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