[English] 日本語

Yorodumi Papers

- Database of articles cited by EMDB/PDB/SASBDB data -

+
Search query

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

-
Structure paper

Title	Structural mechanism of histone H2A.Z exchange by human SRCAP-CFDP1 holoenzyme.
Journal, issue, pages	Sci Adv, Vol. 12, Issue 31, Page eaei7728, Year 2026
Publish date	Jul 31, 2026
Authors	Giho Park / Carl Wu / Robert K Louder /
PubMed Abstract	The conserved yeast SWR1 and human SRCAP chromatin remodeling complexes catalyze exchange of nucleosomal histone H2A for H2A.Z, but the underlying mechanism has remained obscure. Here, we show that ...The conserved yeast SWR1 and human SRCAP chromatin remodeling complexes catalyze exchange of nucleosomal histone H2A for H2A.Z, but the underlying mechanism has remained obscure. Here, we show that histone exchange by SRCAP requires the transient activator CFDP1 and resolve nine cryo-electron microscopy structures of the SRCAP-CFDP1 holoenzyme that define the stepwise exchange mechanism. CFDP1 recognizes the conformation of the fully engaged SRCAP-nucleosome complex through interactions with multiple subunits-including direct contact with the ATPase domain-and induces conformational transitions that drive extensive DNA unwrapping, eviction of the H2A-H2B dimer, and insertion of the H2A.Z-H2B dimer, all without necessarily requiring hydrolysis of bound ATP. Collectively, these findings provide unprecedented insight into the mechanism of activator- and nucleotide-driven histone exchange from nucleosomal H2A to H2A.Z.
External links	Sci Adv / PubMed:42536744 / PubMed Central
Methods	EM (single particle)
Resolution	2.6 - 8.6 Å
Structure data	45381 9ca7 EMDB-45381, PDB-9ca7: Cryo-EM structure of human SRCAP-nucleosome complex in the fully-engaged state (composite structure) Method: EM (single particle) / Resolution: 3.35 Å 45382 9ca8 EMDB-45382, PDB-9ca8: Cryo-EM structure of human SRCAP-nucleosome complex in the partially-engaged state (composite structure) Method: EM (single particle) / Resolution: 3.92 Å 45383 9ca9 EMDB-45383, PDB-9ca9: Cryo-EM structure of the human SRCAP complex in the unbound state (composite structure) Method: EM (single particle) / Resolution: 3.56 Å 45384 9caa EMDB-45384, PDB-9caa: Cryo-EM structure of human SRCAP-nucleosome complex in the pre-engaged state (composite structure) Method: EM (single particle) / Resolution: 4.04 Å 49374 9nfv EMDB-49374, PDB-9nfv: Human SRCAP-CFDP1-nucleosome complex in the poised state of the H2A.Z histone exchange reaction (composite structure) Method: EM (single particle) / Resolution: 3.8 Å 49375 9nfw EMDB-49375, PDB-9nfw: Human SRCAP-CFDP1-nucleosome complex in the activated state of the H2A.Z histone exchange reaction (composite structure) Method: EM (single particle) / Resolution: 3.8 Å 49376 9nfx EMDB-49376, PDB-9nfx: Human SRCAP-CFDP1-hexasome complex in the evicted state of the H2A.Z histone exchange reaction (composite structure) Method: EM (single particle) / Resolution: 3.3 Å 49377 9nfy EMDB-49377, PDB-9nfy: Human SRCAP-CFDP1-prenucleosome complex in the pre-inserted state of the H2A.Z histone exchange reaction (composite structure) Method: EM (single particle) / Resolution: 3.4 Å 49378 9nfz EMDB-49378, PDB-9nfz: Human SRCAP-nucleosome complex in the fully inserted state of the H2A.Z histone exchange reaction (composite structure) Method: EM (single particle) / Resolution: 3.8 Å 49379 9ng0 EMDB-49379, PDB-9ng0: Human SRCAP-nucleosome complex in the pre-dissociation state of the H2A.Z histone exchange reaction (composite structure) Method: EM (single particle) / Resolution: 3.9 Å EMDB-49423: Human SRCAP-CFDP1-nucleosome complex in the poised state of the H2A.Z histone exchange reaction (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 3.8 Å EMDB-49424: RuvBL core from poised state of SRCAP-CFDP1-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.5 Å EMDB-49425: Arp6-ZnHIT1 module from poised state of SRCAP-CFDP1-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 4.0 Å EMDB-49426: ATPase module from poised state of SRCAP-CFDP1-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 4.3 Å EMDB-49427: Nucleosome from poised state of SRCAP-CFDP1-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 4.3 Å EMDB-49428: Human SRCAP-CFDP1-nucleosome complex in the activated state of the H2A.Z histone exchange reaction (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 3.8 Å EMDB-49429: RuvBL core from activated state of SRCAP-CFDP1-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.6 Å EMDB-49430: Arp6-ZnHIT1 module from activated state of SRCAP-CFDP1-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.8 Å EMDB-49431: ATPase module from activated state of SRCAP-CFDP1-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 4.3 Å EMDB-49432: Nucleosome from activated state of SRCAP-CFDP1-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 4.2 Å EMDB-49434: Human SRCAP-CFDP1-hexasome complex in the evicted state of the H2A.Z histone exchange reaction (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 3.4 Å EMDB-49435: RuvBL core from evicted state of SRCAP-CFDP1-hexasome complex (focused refinement) Method: EM (single particle) / Resolution: 3.2 Å EMDB-49436: Arp6-ZnHIT1 module from evicted state of SRCAP-CFDP1-hexasome complex (focused refinement) Method: EM (single particle) / Resolution: 3.4 Å EMDB-49437: ATPase module from evicted state of SRCAP-CFDP1-hexasome complex (focused refinement) Method: EM (single particle) / Resolution: 3.6 Å EMDB-49438: Hexasome from evicted state of SRCAP-CFDP1-hexasome complex (focused refinement) Method: EM (single particle) / Resolution: 3.5 Å EMDB-49439: Prenucleosome from pre-inserted state of SRCAP-CFDP1-prenucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 4.3 Å EMDB-49440: Human SRCAP-nucleosome complex in the fully inserted state of the H2A.Z histone exchange reaction (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 3.8 Å EMDB-49441: RuvBL core from fully inserted state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.5 Å EMDB-49442: Arp6-ZnHIT1 module from fully inserted state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.5 Å EMDB-49443: ATPase module from fully inserted state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.7 Å EMDB-49444: Nucleosome from fully inserted state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.8 Å EMDB-49445: Human SRCAP-nucleosome complex in the pre-dissociation state of the H2A.Z histone exchange (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 3.9 Å EMDB-49446: RuvBL core from pre-dissociation state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.5 Å EMDB-49447: Arp6-ZnHIT1 module from pre-dissociation state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.7 Å EMDB-49448: ATPase module from pre-dissociation state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.8 Å EMDB-49449: Nucleosome from pre-dissociation state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.7 Å EMDB-49770: Cryo-EM structure of human SRCAP-nucleosome complex in the fully-engaged state (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 3.4 Å EMDB-49771: RuvBL core from fully-engaged state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 2.6 Å EMDB-49772: ARP6-ZNHIT1 module from fully-engaged state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.2 Å EMDB-49773: ATPase module from fully-engaged state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.2 Å EMDB-49774: Nucleosome from fully-engaged state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.0 Å EMDB-49775: Cryo-EM structure of human SRCAP-nucleosome complex in the partially-engaged state (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 4.0 Å EMDB-49776: RuvBL core from partially-engaged state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.5 Å EMDB-49777: ARP6-ZNHIT1 module from partially-engaged state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.5 Å EMDB-49778: Nucleosome from partially-engaged state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.9 Å EMDB-49779: ATPase module from partially-engaged state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.8 Å EMDB-49780: Cryo-EM structure of human SRCAP-nucleosome complex in the pre-engaged state (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 4.0 Å EMDB-49781: RuvBL core from pre-engaged state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 3.7 Å EMDB-49782: ARP6-ZNHIT1 module from pre-engaged state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 4.0 Å EMDB-49783: Nucleosome from pre-engaged state of SRCAP-nucleosome complex (focused refinement) Method: EM (single particle) / Resolution: 5.3 Å EMDB-49784: Cryo-EM structure of human SRCAP complex in the unbound state (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 3.6 Å EMDB-49785: RuvBL core from unbound SRCAP complex (focused refinement) Method: EM (single particle) / Resolution: 3.4 Å EMDB-49786: ARP6-ZNHIT1 module from unbound SRCAP complex (focused refinement) Method: EM (single particle) / Resolution: 3.7 Å 71625 9pgc EMDB-71625, PDB-9pgc: Trident submodule from human SRCAP-nucleosome complex in the fully-engaged state (focused refinement) Method: EM (single particle) / Resolution: 3.8 Å 71626 9pgd EMDB-71626, PDB-9pgd: ARP6-ZNHIT1 module from fully-engaged state of SRCAP-nucleosome complex, with H3-bound ARP6 (focused refinement, filtered by local resolution) Method: EM (single particle) / Resolution: 3.2 Å 71627 9y3d EMDB-71627: Human SRCAP-nucleosome complex in the fully-engaged state, with H4-bound GAS41 (unmasked refinement, filtered by local resolution) PDB-9y3d: Extended cryo-EM structure of the human SRCAP-nucleosome complex in the fully-engaged state, with H4-bound GAS41 Method: EM (single particle) / Resolution: 7.1 Å EMDB-71628: Human SRCAP-nucleosome complex in the fully-engaged state, with unbound GAS41 (unmasked refinement, filtered by local resolution) Method: EM (single particle) / Resolution: 6.8 Å 72455 9y3e EMDB-72455: Human SRCAP-nucleosome complex in the pre-engaged state (unmasked refinement filtered by local resolution) PDB-9y3e: Extended cryo-EM structure of human SRCAP-nucleosome complex in the pre-engaged state Method: EM (single particle) / Resolution: 5.0 Å 72456 9y3f EMDB-72456: Human SRCAP-CFDP1-nucleosome complex in the poised state (unmasked refinement filtered by local resolution) PDB-9y3f: Extended cryo-EM structure of human SRCAP-CFDP1-nucleosome complex in the poised state Method: EM (single particle) / Resolution: 4.5 Å 72457 9y3g EMDB-72457: Human SRCAP-CFDP1-nucleosome complex in the activated state (unmasked refinement filtered by local resolution) PDB-9y3g: Extended cryo-EM structure of human SRCAP-CFDP1-nucleosome complex in the activated state Method: EM (single particle) / Resolution: 4.1 Å 72458 9y3h EMDB-72458: Human SRCAP-CFDP1-nucleosome complex in the unwrapping state (unmasked refinement filtered by local resolution) PDB-9y3h: Human SRCAP-CFDP1-nucleosome complex in the unwrapping state of the H2A.Z histone exchange reaction Method: EM (single particle) / Resolution: 4.5 Å EMDB-74291: Human SRCAP-nucleosome complex in the fully-engaged state, subclass with density for sequestered H2A.Z-H2B (unmasked refinement, filtered by local resolution) Method: EM (single particle) / Resolution: 4.2 Å EMDB-74337: Prenucleosome from pre-inserted state of SRCAP-CFDP1-prenucleosome complex, subclass with alternative dimer position B (focused refinement) Method: EM (single particle) / Resolution: 6.7 Å EMDB-74338: Prenucleosome from pre-inserted state of SRCAP-CFDP1-prenucleosome complex, subclass with alternative dimer position C (focused refinement) Method: EM (single particle) / Resolution: 6.5 Å EMDB-74393: ATPase module from evicted state of SRCAP-CFDP1-hexasome complex, subclass with density for CFDP1 FAGE domain (focused refinement) Method: EM (single particle) / Resolution: 4.5 Å 74396 9zla EMDB-74396, PDB-9zla: Unbound 106-N-32 nucleosome from SRCAP-CFDP1-nucleosome binding reaction Method: EM (single particle) / Resolution: 3.1 Å EMDB-74416: Trident submodule from human SRCAP-CFDP1-nucleosome complex in the poised state (focused refinement) Method: EM (single particle) / Resolution: 7.7 Å EMDB-74463: Evicted state of the human SRCAP-CFDP1-hexasome complex formed in the presence of ADP-BeFx (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 7.3 Å EMDB-74464: Evicted state of the human SRCAP-CFDP1-hexasome complex formed in the presence of ADP-Vi (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 7.0 Å EMDB-74476: Evicted state of the human SRCAP-CFDP1-hexasome complex formed in the presence of AMP-PNP (composite structure) Method: EM (single particle) / Resolution: 4.0 Å EMDB-74500: Evicted state of the human SRCAP-CFDP1-hexasome complex formed in the presence of ATP (composite structure) Method: EM (single particle) / Resolution: 3.2 Å EMDB-74551: Evicted state of the human SRCAP-CFDP1-hexasome complex formed in the presence of AMP-PNP (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 4.0 Å EMDB-74552: RuvBL core from evicted state of SRCAP-CFDP1-hexasome complex formed in the presence of AMP-PNP (focused refinement) Method: EM (single particle) / Resolution: 3.7 Å EMDB-74553: Arp6-ZnHIT1 module from evicted state of SRCAP-CFDP1-hexasome complex formed in the presence of AMP-PNP (focused refinement) Method: EM (single particle) / Resolution: 5.8 Å EMDB-74554: ATPase module from evicted state of SRCAP-CFDP1-hexasome complex formed in the presence of AMP-PNP (focused refinement) Method: EM (single particle) / Resolution: 5.7 Å EMDB-74555: Hexasome from evicted state of SRCAP-CFDP1-hexasome complex formed in the presence of AMP-PNP (focused refinement) Method: EM (single particle) / Resolution: 6.3 Å EMDB-74556: Evicted state of the human SRCAP-CFDP1-hexasome complex formed in the presence of ATP (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 3.2 Å EMDB-74557: RuvBL core from evicted state of SRCAP-CFDP1-hexasome complex formed in the presence of ATP (focused refinement) Method: EM (single particle) / Resolution: 3.0 Å EMDB-74558: Arp6-ZnHIT1 module from evicted state of SRCAP-CFDP1-hexasome complex formed in the presence of ATP (focused refinement) Method: EM (single particle) / Resolution: 3.1 Å EMDB-74559: ATPase module from evicted state of SRCAP-CFDP1-hexasome complex formed in the presence of ATP (focused refinement) Method: EM (single particle) / Resolution: 3.7 Å EMDB-74560: Hexasome from evicted state of SRCAP-CFDP1-hexasome complex formed in the presence of ATP (focused refinement) Method: EM (single particle) / Resolution: 3.3 Å EMDB-74619: Activated state of the human SRCAP-CFDP1-nucleosome complex formed in the presence of ATP-gamma-S (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 4.7 Å EMDB-74620: RuvBL core from activated state of SRCAP-CFDP1-nucleosome complex formed in the presence of ATP-gamma-S (focused refinement) Method: EM (single particle) / Resolution: 4.1 Å EMDB-74621: Arp6-ZnHIT1 module from activated state of SRCAP-CFDP1-nucleosome complex formed in the presence of ATP-gamma-S (focused refinement) Method: EM (single particle) / Resolution: 5.9 Å EMDB-74622: ATPase module from activated state of SRCAP-CFDP1-nucleosome complex formed in the presence of ATP-gamma-S (focused refinement) Method: EM (single particle) / Resolution: 6.4 Å EMDB-74623: Nucleosome from activated state of SRCAP-CFDP1-nucleosome complex formed in the presence of ATP-gamma-S (focused refinement) Method: EM (single particle) / Resolution: 4.7 Å EMDB-74624: Activated state of the human SRCAP-CFDP1-nucleosome complex formed in the presence of ATP-gamma-S (composite map) Method: EM (single particle) / Resolution: 4.7 Å EMDB-74639: Fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of ATP-gamma-S and absence of CFDP1 (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 3.7 Å EMDB-74640: RuvBL core from fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of ATP-gamma-S and absence of CFDP1 (focused refinement) Method: EM (single particle) / Resolution: 3.4 Å EMDB-74641: ARP6-ZNHIT1 module from fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of ATP-gamma-S and absence of CFDP1 (focused refinement) Method: EM (single particle) / Resolution: 3.5 Å EMDB-74642: ATPase module from fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of ATP-gamma-S and absence of CFDP1 (focused refinement) Method: EM (single particle) / Resolution: 3.8 Å EMDB-74643: Nucleosome from fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of ATP-gamma-S and absence of CFDP1 (focused refinement) Method: EM (single particle) / Resolution: 3.6 Å EMDB-74644: Fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of ATP-gamma-S and absence of CFDP1 (composite map) Method: EM (single particle) / Resolution: 3.7 Å EMDB-74657: Pre-engaged state of the human SRCAP-nucleosome complex formed in the absence added nucleotide (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 8.6 Å EMDB-74658: Fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of ATP and absence of CFDP1 (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 4.7 Å EMDB-74664: Fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of AMP-PNP and absence of CFDP1 (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 3.9 Å EMDB-74665: RuvBL core from fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of AMP-PNP and absence of CFDP1 (focused refinement) Method: EM (single particle) / Resolution: 3.4 Å EMDB-74666: ARP6-ZNHIT1 module from fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of AMP-PNP and absence of CFDP1 (focused refinement) Method: EM (single particle) / Resolution: 3.9 Å EMDB-74667: ATPase module from fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of AMP-PNP and absence of CFDP1 (focused refinement) Method: EM (single particle) / Resolution: 3.9 Å EMDB-74668: Nucleosome from fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of AMP-PNP and absence of CFDP1 (focused refinement) Method: EM (single particle) / Resolution: 3.7 Å EMDB-74670: Fully-engaged state of the human SRCAP-nucleosome complex formed in the presence of AMP-PNP and absence of CFDP1 (composite map) Method: EM (single particle) / Resolution: 3.9 Å EMDB-74678: Poised state of the human SRCAP-CFDP1(delta284-299)-nucleosome mutant complex formed in the presence of ATP-gamma-S (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 3.6 Å EMDB-74680: RUVBL core from poised state of the human SRCAP-CFDP1(delta284-299)-nucleosome mutant complex formed in the presence of ATP-gamma-S (focused refinement) Method: EM (single particle) / Resolution: 3.4 Å EMDB-74681: ARP6-ZNHIT1 module from poised state of the human SRCAP-CFDP1(delta284-299)-nucleosome mutant complex formed in the presence of ATP-gamma-S (focused refinement) Method: EM (single particle) / Resolution: 3.4 Å EMDB-74683: ATPase module from poised state of the human SRCAP-CFDP1(delta284-299)-nucleosome mutant complex formed in the presence of ATP-gamma-S (focused refinement) Method: EM (single particle) / Resolution: 3.6 Å EMDB-74684: Nucleosome from poised state of the human SRCAP-CFDP1(delta284-299)-nucleosome mutant complex formed in the presence of ATP-gamma-S (focused refinement) Method: EM (single particle) / Resolution: 3.7 Å EMDB-74685: Poised state of the human SRCAP-CFDP1(delta284-299)-nucleosome mutant complex formed in the presence of ATP-gamma-S (composite map) Method: EM (single particle) / Resolution: 3.6 Å EMDB-74692: Fully inserted state of the human SRCAP-nucleosome complex formed in the presence of ATP (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 4.0 Å EMDB-74694: RUVBL core from fully inserted state of the human SRCAP-nucleosome complex formed in the presence of ATP (focused refinement) Method: EM (single particle) / Resolution: 3.4 Å EMDB-74695: ARP6-ZNHIT1 module from fully inserted state of the human SRCAP-nucleosome complex formed in the presence of ATP (focused refinement) Method: EM (single particle) / Resolution: 4.3 Å EMDB-74696: ATPase module from fully inserted state of the human SRCAP-nucleosome complex formed in the presence of ATP (focused refinement) Method: EM (single particle) / Resolution: 5.6 Å EMDB-74697: Nucleosome from fully inserted state of the human SRCAP-nucleosome complex formed in the presence of ATP (focused refinement) Method: EM (single particle) / Resolution: 4.1 Å EMDB-74698: Fully inserted state of the human SRCAP-nucleosome complex formed in the presence of ATP (composite map) Method: EM (single particle) / Resolution: 4.0 Å EMDB-74735: Activated state of the human SRCAP-CFDP1-nucleosome complex formed in the presence of ADP (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 4.5 Å EMDB-74736: Poised state of the human SRCAP-CFDP1-nucleosome complex formed in the presence of ADP (consensus map filtered by local resolution) Method: EM (single particle) / Resolution: 4.3 Å
Chemicals	ChemComp-AGS: PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER / ATP-gamma-S, energy-carrying molecule analogueYM ChemComp-MG: Unknown entry ChemComp-ZN: Unknown entry ChemComp-ADP: ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying moleculeYM ChemComp-ATP: ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM
Source	homo sapiens (human) xenopus laevis (African clawed frog) synthetic construct (others)
Keywords	GENE REGULATION / Chromatin Remodeler / Snf2 family ATPase / H2A.Z / HYDROLASE/DNA BINDING PROTEIN/DNA / HYDROLASE-DNA BINDING PROTEIN-DNA complex

+
About Yorodumi Papers

-
News

-
Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

Version 3 of the EMDB header file is now the official format.
The previous official version 1.9 will be removed from the archive.

Related info.:EMDB header

External links:wwPDB to switch to version 3 of the EMDB data model

-
Aug 12, 2020. Covid-19 info

Covid-19 info

URL: https://pdbj.org/emnavi/covid19.php

New page: Covid-19 featured information page in EM Navigator.

Related info.:Covid-19 info / Mar 5, 2020. Novel coronavirus structure data

+
Mar 5, 2020. Novel coronavirus structure data

+
Jan 31, 2019. EMDB accession codes are about to change! (news from PDBe EMDB page)

+
Jul 12, 2017. Major update of PDB

-
Yorodumi Papers

Database of articles cited by EMDB/PDB/SASBDB data

Database of articles cited by EMDB, PDB, and SASBDB entries
Using PubMed data

Related info.:EMDB / PDB / SASBDB / Yorodumi / EMN Papers / Changes in new EM Navigator and Yorodumi