Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	UFC1 reveals the multifactorial and plastic nature of oxyanion holes in E2 conjugating enzymes.
Journal, issue, pages	Nat Commun, Vol. 16, Page 3912-3912, Year 2025
Publish date	Aug 27, 2024 (structure data deposition date)
Authors	Kumar, M. / Banerjee, S. / Cohen-Kfir, E. / Mitelberg, M.B. / Tiwari, S. / Isupov, M.N. / Dessau, M. / Wiener, R.
External links	Nat Commun / PubMed:40280917
Methods	X-ray diffraction
Resolution	1.115 - 2.051 Å
Structure data	PDB-9glh: Crystal Structure of UFC1 T106S Method: X-RAY DIFFRACTION / Resolution: 1.115 Å PDB-9gli: Crystal Structure of UFC1 T106C Method: X-RAY DIFFRACTION / Resolution: 1.426 Å PDB-9glj: Crystal Structure of UFC1 T106A Method: X-RAY DIFFRACTION / Resolution: 1.213 Å PDB-9glk: Crystal Structure of UFC1 E149I Method: X-RAY DIFFRACTION / Resolution: 2.03 Å PDB-9gll: Crystal Structure of UFC1 T106L Method: X-RAY DIFFRACTION / Resolution: 1.65 Å PDB-9glm: Crystal Structure of UFC1 W145F Method: X-RAY DIFFRACTION / Resolution: 1.79 Å PDB-9gln: Crystal Structure of UFC1 C116E Method: X-RAY DIFFRACTION / Resolution: 1.92 Å PDB-9glo: Crystal Structure of UFC1 C116E&T106S Method: X-RAY DIFFRACTION / Resolution: 1.53 Å PDB-9glp: Crystal Structure of UFC1 C116E&T106I Method: X-RAY DIFFRACTION / Resolution: 1.77 Å PDB-9glr: Crystal Structure of Human UBC9 C93E Method: X-RAY DIFFRACTION / Resolution: 1.72 Å PDB-9gls: Crystal Structure of Human UBCH5B C85E Method: X-RAY DIFFRACTION / Resolution: 1.25 Å PDB-9glt: Crystal Structure of Yeast Ubc13 C87E Method: X-RAY DIFFRACTION / Resolution: 1.45 Å PDB-9gmm: Crystal Structure of UFC1 T106I Method: X-RAY DIFFRACTION / Resolution: 1.35 Å PDB-9gmn: Crystal Structure of UFC1 T106V Method: X-RAY DIFFRACTION / Resolution: 2 Å PDB-9gn8: Crystal Structure of UFC1 E149D Method: X-RAY DIFFRACTION / Resolution: 1.96 Å PDB-9i9m: Crystal structure of chimeric UFC1, TAK MotiF replaced with HPN motif of other E2 proteins Method: X-RAY DIFFRACTION / Resolution: 1.543 Å PDB-9i9n: Crystal Structure of UFC1 C116E & K108A Method: X-RAY DIFFRACTION / Resolution: 1.88 Å PDB-9i9o: Crystal Structure of UFC1 K108M Method: X-RAY DIFFRACTION / Resolution: 2.051 Å PDB-9i9p: Crystal Structure of UFC1 W145H Method: X-RAY DIFFRACTION / Resolution: 2.022 Å PDB-9ia8: Crystal Structure of UFC1 K108R Method: X-RAY DIFFRACTION / Resolution: 1.9 Å
Chemicals	ChemComp-SO4: SULFATE ION ChemComp-HOH: WATER ChemComp-GOL: GLYCEROL ChemComp-IMD: IMIDAZOLE ChemComp-EDO: 1,2-ETHANEDIOL ChemComp-FMT: FORMIC ACID ChemComp-NA: Unknown entry
Source	homo sapiens (human) saccharomyces cerevisiae (brewer's yeast)
Keywords	LIGASE / UFM1 conjugating enzyme1 / UBC core domain containing protein / Brain development / Infantile encephalopathy / UFC1~UFM1 thioester mimic / SUMO-1 conjugating enzyme / Ubiquitin conjugating protein / SUMOLYATION Pathway protein / E2~SUMO thioester complex mimic / E2~UB thioester mimic / Ubiquitin conjugating protein E2 UBC13~UB thioester complex mimic / UFM1 conjugation / UFMylation pathway component / UFM1 conjugating enzyme activity / Ubiquitin fold modifier conjugating enzyme-1 / UFMylation / Chimeric UFC1 / HPN motif / Isopeptide / oxyanion hole / Ubiquitin fold modifier conjugation enzyme 1 / UFC1 / transthiolation activity / Ligase activity / aminoacyl transferase activity / Thioester mimetic / transthiolation / isopeptide bond / Thioester / UFM1 conjugating enzyme / aminoacyltransferase activity / oxyanion hole impairing mutation / Ubiquitin-fold modifier-conjugating enzyme 1 / UFM1 transferring enzyme