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Structure paper

TitleArchitecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
Journal, issue, pagesCell, Vol. 170, Issue 6, Page 1247-1257.e12, Year 2017
Publish dateAug 23, 2017
AuthorsRunyu Guo / Shuai Zong / Meng Wu / Jinke Gu / Maojun Yang
External linksPubMed:28844695 / Publisher's page
MethodsEM (single particle)
Resolution3.4 - 17.4 A
Structure data

EMDB-6771:
Cryo-EM structure of human respiratory complex I matrix arm

EMDB-6772:
Cryo-EM structure of human respiratory complex I transmembrane arm

EMDB-6773:
Cryo-EM structure of human respiratory complex I

EMDB-6774:
Cryo-EM structure of human respiratory complex III (cytochrome bc1 complex)

PDB-5xtb:
Cryo-EM structure of human respiratory complex I matrix arm

PDB-5xtc:
Cryo-EM structure of human respiratory complex I transmembrane arm

PDB-5xtd:
Cryo-EM structure of human respiratory complex I

PDB-5xte:
Cryo-EM structure of human respiratory complex III (cytochrome bc1 complex)

EMDB-6775:
Cryo-EM structure of human respiratory supercomplex I1III2IV1

EMDB-6776:
Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2

PDB-5xth:
Cryo-EM structure of human respiratory supercomplex I1III2IV1

PDB-5xti:
Cryo-EM architecture of human respiratory chain megacomplex-I2III2IV2

Chemicals

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-FMN:
FLAVIN MONONUCLEOTIDE

ChemComp-8Q1:
S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate

ChemComp-NDP:
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE

ChemComp-FES:
FE2/S2 (INORGANIC) CLUSTER

ChemComp-PLX:
(9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL

ChemComp-CDL:
CARDIOLIPIN

ChemComp-PEE:
1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine

ChemComp-HEC:
HEME C

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-CU:
COPPER (II) ION

ChemComp-MG:
MAGNESIUM ION

ChemComp-HEA:
HEME-A

ChemComp-ZN:
ZINC ION

SourceHomo sapiens / human
Bos taurus / mammal / ウシ /
KeywordsOXIDOREDUCTASE/ELECTRON TRANSPORT / Respiratory / OXIDOREDUCTASE-ELECTRON TRANSPORT complex / ELECTRON TRANSPORT / Homo sapiens / Oxidoreductase / Complex / Supercomplex

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