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Structure paper

TitleGenome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Journal, issue, pagesMol. Biochem. Parasitol., Vol. 151, Page 100-110, Year 2007
Publish dateJul 5, 2004 (structure data deposition date)
AuthorsVedadi, M. / Lew, J. / Artz, J. / Amani, M. / Zhao, Y. / Dong, A. / Wasney, G.A. / Gao, M. / Hills, T. / Brokx, S. ...Vedadi, M. / Lew, J. / Artz, J. / Amani, M. / Zhao, Y. / Dong, A. / Wasney, G.A. / Gao, M. / Hills, T. / Brokx, S. / Qiu, W. / Sharma, S. / Diassiti, A. / Alam, Z. / Melone, M. / Mulichak, A. / Wernimont, A. / Bray, J. / Loppnau, P. / Plotnikova, O. / Newberry, K. / Sundararajan, E. / Houston, S. / Walker, J. / Tempel, W. / Bochkarev, A. / Kozieradzki, I. / Edwards, A. / Arrowsmith, C. / Roos, D. / Kain, K. / Hui, R.
External linksMol. Biochem. Parasitol. / PubMed:17125854
MethodsX-ray diffraction
Resolution1.6 - 2.8 Å
Structure data

PDB-1txj:
Crystal structure of translationally controlled tumour-associated protein (TCTP) from Plasmodium knowlesi
Method: X-RAY DIFFRACTION / Resolution: 2.0 Å

PDB-1xcc:
1-Cys peroxidoxin from Plasmodium Yoelli
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-1y6z:
Middle domain of Plasmodium falciparum putative heat shock protein PF14_0417
Method: X-RAY DIFFRACTION / Resolution: 1.88 Å

PDB-1z6g:
Crystal structure of guanylate kinase from Plasmodium falciparum
Method: X-RAY DIFFRACTION / Resolution: 2.18 Å

PDB-1z7d:
Ornithine aminotransferase PY00104 from Plasmodium Yoelii
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-1z81:
Crystal Structure of cyclophilin from Plasmodium yoelii.
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-1zo2:
Structure of nuclear transport factor 2 (Ntf2) from Cryptosporidium parvum
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-2a22:
Structure of Vacuolar Protein Sorting 29 from Cryptosporidium Parvum
Method: X-RAY DIFFRACTION / Resolution: 2.198 Å

PDB-2a4a:
Deoxyribose-phosphate aldolase from P. yoelii
Method: X-RAY DIFFRACTION / Resolution: 1.84 Å

PDB-2aif:
Crystal Structure of High Mobility Like Protein, NHP2, putative from Cryptosporidium parvum
Method: X-RAY DIFFRACTION / Resolution: 1.895 Å

PDB-2amx:
Crystal structure of Plasmodium Yoelii Adenosine deaminase (PY02076)
Method: X-RAY DIFFRACTION / Resolution: 2.02 Å

PDB-2aqw:
Structure of putative orotidine-monophosphate-decarboxylase from Plasmodium yoelii (PY01515)
Method: X-RAY DIFFRACTION / Resolution: 2.0 Å

PDB-2av4:
Crystal structure of Plasmodium yoelii thioredoxin-like protein 4A (DIM1)
Method: X-RAY DIFFRACTION / Resolution: 1.73 Å

PDB-2awp:
Crystal structure of Plasmodium knowlesi structure of Iron Super-Oxide Dismutase
Method: X-RAY DIFFRACTION / Resolution: 2.0 Å

PDB-2ayv:
Crystal structure of a putative ubiquitin-conjugating enzyme E2 from Toxoplasma gondii
Method: X-RAY DIFFRACTION / Resolution: 2.001 Å

PDB-2b71:
Plasmodium yoelii cyclophilin-like protein
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2bdd:
Crystal Structure of Holo-ACP-synthase from Plasmodium yoelii
Method: X-RAY DIFFRACTION / Resolution: 2.28 Å

PDB-2f4z:
Toxoplasma gondii ubiquitin conjugating enzyme TgTwinScan_2721- E2 domain
Method: X-RAY DIFFRACTION / Resolution: 2.11 Å

PDB-2fds:
Crystal Structure of Plasmodium Berghei Orotidine 5'-monophosphate Decarboxylase (ortholog of Plasmodium falciparum PF10_0225)
Method: X-RAY DIFFRACTION / Resolution: 1.72 Å

PDB-2ffc:
Crystal Structure of Plasmodium Vivax Orotidine-Monophosphate-Decarboxyl UMP Bound
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-2fo3:
Plasmodium vivax ubiquitin conjugating enzyme E2
Method: X-RAY DIFFRACTION / Resolution: 1.86 Å

PDB-2fu0:
Plasmodium falciparum cyclophilin PFE0505w putative cyclosporin-binding domain
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-2ghi:
Crystal Structure of Plasmodium yoelii Multidrug Resistance Protein 2
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-2h1r:
Crystal structure of a dimethyladenosine transferase from Plasmodium falciparum
Method: X-RAY DIFFRACTION / Resolution: 1.89 Å

PDB-2h2y:
Crystal structure of ubiquitin conjugating enzyme E2 from plasmodium falciparum
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-2h66:
The Crystal Structure of Plasmodium Vivax 2-Cys peroxiredoxin
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-2hjr:
Crystal Structure of Cryptosporidium parvum malate dehydrogenase
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-2hte:
The crystal structure of spermidine synthase from p. falciparum in complex with 5'-methylthioadenosine
Method: X-RAY DIFFRACTION / Resolution: 2.0 Å

PDB-2hvg:
Crystal Structure of Adenylosuccinate Lyase from Plasmodium Vivax
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3pgg:
Crystal structure of cryptosporidium parvum u6 snrna-associated sm-like protein lsm5
Method: X-RAY DIFFRACTION / Resolution: 2.14 Å

PDB-3tb2:
1-Cys peroxidoxin from Plasmodium Yoelli
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-HOH:
WATER / Water

ChemComp-SO4:
SULFATE ION / Sulfate

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM / HEPES

ChemComp-CO:
Unknown entry

ChemComp-UNX:
Unknown entry

ChemComp-IOD:
IODIDE ION / Iodide

ChemComp-CL:
Unknown entry / Chloride

ChemComp-GOL:
GLYCEROL / Glycerol

ChemComp-U5P:
URIDINE-5'-MONOPHOSPHATE / Uridine monophosphate

ChemComp-CIT:
CITRIC ACID / Citric acid

ChemComp-APR:
ADENOSINE-5-DIPHOSPHORIBOSE

ChemComp-MTA:
5'-DEOXY-5'-METHYLTHIOADENOSINE / 5′-Methylthioadenosine

ChemComp-1PG:
2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL / Polyethylene glycol

ChemComp-EDO:
1,2-ETHANEDIOL / Ethylene glycol

Source
  • plasmodium knowlesi (eukaryote)
  • plasmodium yoelii (eukaryote)
  • plasmodium falciparum (malaria parasite P. falciparum)
  • plasmodium yoelii yoelii (eukaryote)
  • cryptosporidium parvum (eukaryote)
  • toxoplasma gondii (eukaryote)
  • plasmodium berghei (eukaryote)
  • plasmodium vivax (malaria parasite P. vivax)
  • plasmodium yoelii yoelii str. 17xnl (eukaryote)
  • plasmodium falciparum 3d7 (eukaryote)
KeywordsSTRUCTURAL GENOMICS / UNKNOWN FUNCTION / Structural Genomics Consortium / SGC / guanine nucleotide-free chaperones / guanine nucleotide exchange factor / beta-sandwich / helix-turn-helix / heat shock / chaperone / TRANSFERASE / guanylate kinase / malaria / plasmodium yoelii / ornithine aminotransferase / ISOMERASE / TRANSPORT PROTEIN / NUCLEAR TRANSPORT / PROTEIN TRANSPORT / VACUOLAR PROTEIN SORTING PROTEIN / ALPHA-BETA-BETA-ALPHA SANDWICH / LYASE / ALDOLASE / TIM BETA/ALPHA BARREL / DEOC / DERA / DNA BINDING PROTEIN / CYTOKINE / ribosomal protein / High-mobility like protein / Transcription factor / HYDROLASE / Plasmodium Yoelii Adenosine deaminase (PY02076) / decarboxylase PY01515 SGC / thioredoxin-like protein / DIM1 / U5 snRNP-specific 15kD protein / OXIDOREDUCTASE / Iron Super-Oxide Dismutase / LIGASE / ubiquitin / ubiquitin-conjugating enzyme / cyclophilin / ACP synthase / ubiquitin conjugating TgTwinScan_2721 / TIM barrel / DECARBOXYLASE / PV-PF10_0225 / UBC / PFE0505w / cyclosporin-binding domain / Multidrug Resistance Protein / MDR / SGC Toronto dimethyladenosine transferase / STRUCTURAL GENOMICS/OXIDOREDUCTASE / plasmodium / vivax / peroxiredoxin / STRUCTURAL GENOMICS-OXIDOREDUCTASE COMPLEX / malate dehydrogenase / Cryptosporidium parvum / spermidine synthase / alpha helical / U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN / LSM5

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