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Showing all 45 items for (author: suarez & j)

EMDB-45592: 
13-pf microtubule from the LRRK2(I2020T) and MLi-2 dataset
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45593: 
Focused refinement map of WD40:ARM/ANK interface from LRRK2(I2020T) MLi-2 dataset
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45594: 
Full-length autoinhibited LRRK2(I2020T) co-polymerized with microtubules and MLi-2
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45595: 
Full-length autoinhibited LRRK2 on microtubules with MLi-2
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45596: 
Full-length autoinhibited LRRK2 on microtubules with GZD-824
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-48263: 
Cryo-EM structure of Human NLRP3 complex with compound 1
Method: single particle / : Mammoliti O, Carbajo RJ, Perez-Benito L, Yu X, Prieri MLC, Bontempi L, Embrechts S, Paesmans I, Bassi M, Bhattacharya A, Roman SC, Hoog SD, Demin S, Gijsen HJM, Hache G, Jacobs T, Jerhaoui S, Leenaerts J, Lutter FH, Matico R, Oehlrich D, Perrier M, Ryabchuk P, Schepens W, Sharma S, Somers M, Suarez J, Surkyn M, Opdenbosch NV, Verhulst T, Bottelbergs A

EMDB-48288: 
Human NLRP3 complex with compound 2 in the closed hexamer
Method: single particle / : Mammoliti O, Carbajo RJ, Perez-Benito L, Yu X

EMDB-48289: 
Cryo-EM structure of Human NLRP3 complex with compound 3
Method: single particle / : Mammoliti O, Carbajo RJ, Perez-Benito L, Yu X, Prieri MLC, Bontempi L, Embrechts S, Paesmans I, Bassi M, Bhattacharya A, Roman SC, Hoog SD, Demin S, Gijsen HJM, Hache G, Jacobs T, Jerhaoui S, Leenaerts J, Lutter FH, Matico R, Oehlrich D, Perrier M, Ryabchuk P, Schepens W, Sharma S, Somers M, Suarez J, Surkyn M, Opdenbosch NV, Verhulst T, Bottelbergs A

PDB-9mgy: 
Cryo-EM structure of Human NLRP3 complex with compound 1
Method: single particle / : Mammoliti O, Carbajo RJ, Perez-Benito L, Yu X, Prieri MLC, Bontempi L, Embrechts S, Paesmans I, Bassi M, Bhattacharya A, Roman SC, Hoog SD, Demin S, Gijsen HJM, Hache G, Jacobs T, Jerhaoui S, Leenaerts J, Lutter FH, Matico R, Oehlrich D, Perrier M, Ryabchuk P, Schepens W, Sharma S, Somers M, Suarez J, Surkyn M, Opdenbosch NV, Verhulst T, Bottelbergs A

PDB-9mie: 
Human NLRP3 complex with compound 2 in the closed hexamer
Method: single particle / : Mammoliti O, Carbajo RJ, Perez-Benito L, Yu X

PDB-9mig: 
Cryo-EM structure of Human NLRP3 complex with compound 3
Method: single particle / : Mammoliti O, Carbajo RJ, Perez-Benito L, Yu X, Prieri MLC, Bontempi L, Embrechts S, Paesmans I, Bassi M, Bhattacharya A, Roman SC, Hoog SD, Demin S, Gijsen HJM, Hache G, Jacobs T, Jerhaoui S, Leenaerts J, Lutter FH, Matico R, Oehlrich D, Perrier M, Ryabchuk P, Schepens W, Sharma S, Somers M, Suarez J, Surkyn M, Opdenbosch NV, Verhulst T, Bottelbergs A

EMDB-46855: 
Cryo-EM structure of NLRP3 complex with Compound C
Method: single particle / : Matico R, Grauwen K, Van Gool M, Muratore EM, Yu X, Abdiaj I, Adhikary S, Adriaensen I, Aranzazu GM, Alcazar J, Bassi M, Brisse E, Canellas S, Chaudhuri S, Chauhan D, Delgado F, Dieguez-Vazquez A, Du Jardin M, Eastham V, Finley M, Jacobs T, Keustermans K, Kuhn R, Llaveria J, Leenaerts J, Linares ML, Martin ML, Martinez C, Miller R, Munoz FM, Nooyens A, Perez LB, Perrier M, Pietrak B, Serre J, Sharma S, Somers M, Suarez J, Tresadern G, Trabanco AA, Van den Bulck D, Van Hauwermeiren F, Varghese T, Vega JA, Youssef SA, Edwards MJ, Oehlrich D, Van Opdenbosch N

PDB-9dh3: 
Cryo-EM structure of NLRP3 complex with Compound C
Method: single particle / : Matico R, Grauwen K, Van Gool M, Muratore EM, Yu X, Abdiaj I, Adhikary S, Adriaensen I, Aranzazu GM, Alcazar J, Bassi M, Brisse E, Canellas S, Chaudhuri S, Chauhan D, Delgado F, Dieguez-Vazquez A, Du Jardin M, Eastham V, Finley M, Jacobs T, Keustermans K, Kuhn R, Llaveria J, Leenaerts J, Linares ML, Martin ML, Martinez C, Miller R, Munoz FM, Nooyens A, Perez LB, Perrier M, Pietrak B, Serre J, Sharma S, Somers M, Suarez J, Tresadern G, Trabanco AA, Van den Bulck D, Van Hauwermeiren F, Varghese T, Vega JA, Youssef SA, Edwards MJ, Oehlrich D, Van Opdenbosch N

EMDB-45591: 
Autoinhibited full-length LRRK2(I2020T) on microtubules with MLi-2
Method: subtomogram averaging / : Chen S, Villa E, Leschziner AE

PDB-9cho: 
Autoinhibited full-length LRRK2(I2020T) on microtubules with MLi-2
Method: subtomogram averaging / : Chen S, Villa E, Leschziner AE

EMDB-40811: 
Cryo-EM structure of NLRP3 open octamer
Method: single particle / : Yu X, Matico RE, Miller R, Schoubroeck BV, Grauwen K, Suarez J, Pietrak B, Haloi N, Yin Y, Tresadern GJ, Perez-Benito L, Lindahl E, Bottelbergs A, Oehlrich D, Opdenbosch NV, Sharma S

EMDB-40820: 
Cryo-EM structure of NLRP3 closed hexamer
Method: single particle / : Yu X, Matico RE, Miller R, Schoubroeck BV, Grauwen K, Suarez J, Pietrak B, Haloi N, Yin Y, Tresadern GJ, Perez-Benito L, Lindahl E, Bottelbergs A, Oehlrich D, Opdenbosch NV, Sharma S

EMDB-40855: 
Structure of NLRP3 and NEK7 complex
Method: single particle / : Yu X, Matico RE, Miller R, Schoubroeck BV, Grauwen K, Suarez J, Pietrak B, Haloi N, Yin Y, Tresadern GJ, Perez-Benito L, Lindahl E, Bottelbergs A, Oehlrich D, Opdenbosch NV, Sharma S

PDB-8swf: 
Cryo-EM structure of NLRP3 open octamer
Method: single particle / : Yu X, Matico RE, Miller R, Schoubroeck BV, Grauwen K, Suarez J, Pietrak B, Haloi N, Yin Y, Tresadern GJ, Perez-Benito L, Lindahl E, Bottelbergs A, Oehlrich D, Opdenbosch NV, Sharma S

PDB-8swk: 
Cryo-EM structure of NLRP3 closed hexamer
Method: single particle / : Yu X, Matico RE, Miller R, Schoubroeck BV, Grauwen K, Suarez J, Pietrak B, Haloi N, Yin Y, Tresadern GJ, Perez-Benito L, Lindahl E, Bottelbergs A, Oehlrich D, Opdenbosch NV, Sharma S

PDB-8sxn: 
Structure of NLRP3 and NEK7 complex
Method: single particle / : Yu X, Matico RE, Miller R, Schoubroeck BV, Grauwen K, Suarez J, Pietrak B, Haloi N, Yin Y, Tresadern GJ, Perez-Benito L, Lindahl E, Bottelbergs A, Oehlrich D, Opdenbosch NV, Sharma S

EMDB-41709: 
Structure of C-terminal LRRK2 bound to MLi-2
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio-Louro J, Leschziner A

EMDB-41728: 
Structure of the C-terminal half of LRRK2 bound to GZD-824 (G2019S mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41753: 
Structure of the C-terminal half of LRRK2 bound to GZD-824 (I2020T mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41754: 
Structure of C-terminal LRRK2 bound to MLi-2 (G2019S mutant)
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio-Louro J, Leschziner A

EMDB-41756: 
Structure of C-terminal half of LRRK2 bound to GZD-824
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41757: 
Structure of full length LRRK2 bound to GZD-824 (I2020T mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41758: 
Structure of C-terminal LRRK2 bound to MLi-2 (I2020T mutant)
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio Louro J, Leschziner A

EMDB-41759: 
Structure of full-length LRRK2 bound to MLi-2 (I2020T mutant)
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio Louro J, Leschziner A

EMDB-41794: 
Structure of C-terminal half of LRRK2 (I2020T mutant) bound to GZD-824, Kinase-WD40
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41795: 
Structure of C-terminal half of LRRK2 (I2020T mutant) bound to GZD-824, ROC-COR domain
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41797: 
Structure of C-terminal half of LRRK2 (G2019S mutant) bound to GZD-824, ROC-COR domain
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41798: 
Structure of C-terminal half of LRRK2 bound tp GZFD-824 (G2019S mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41799: 
Structure of C-terminal half of LRRK2 bound to GZD-824 (G2019S mutant), Kinase-WD40
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

EMDB-41802: 
Structure of C-terminal half of LRRK2 bound to GZD-824 (I2020T mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

PDB-8txz: 
Structure of C-terminal LRRK2 bound to MLi-2
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio-Louro J, Leschziner A

PDB-8tyq: 
Structure of the C-terminal half of LRRK2 bound to GZD-824 (G2019S mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

PDB-8tzb: 
Structure of the C-terminal half of LRRK2 bound to GZD-824 (I2020T mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

PDB-8tzc: 
Structure of C-terminal LRRK2 bound to MLi-2 (G2019S mutant)
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio-Louro J, Leschziner A

PDB-8tze: 
Structure of C-terminal half of LRRK2 bound to GZD-824
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

PDB-8tzf: 
Structure of full length LRRK2 bound to GZD-824 (I2020T mutant)
Method: single particle / : Villagran-Suarez A, Sanz-Murillo M, Alegrio-Louro J, Leschziner A

PDB-8tzg: 
Structure of C-terminal LRRK2 bound to MLi-2 (I2020T mutant)
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio Louro J, Leschziner A

PDB-8tzh: 
Structure of full-length LRRK2 bound to MLi-2 (I2020T mutant)
Method: single particle / : Sanz-Murillo M, Villagran-Suarez A, Alegrio Louro J, Leschziner A
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