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Showing 1 - 50 of 87 items for (author: suarez & j)

EMDB-72649: 
Leucine Rich Repeat Kinase 2 bound to GMP-PNP (inactive)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-72656: 
Leucine Rich Repeat Kinase 2 bound to GMP-PNP (active)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-72751: 
LRRK2 asymmetric dimer
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-72756: 
Leucine Rich Repeat Kinase 2 activate state (Apo ROC state 2)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-72762: 
Leucine Rich Repeat Kinase 2 activate state (Apo ROC state 1)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-72768: 
Leucine Rich Repeat Kinase 2 R1441C mutant (active)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-72940: 
LRRK2 activated (flexible C-terminus)
Method: single particle / : Villagran Suarez AC, Bodrug T

EMDB-72941: 
Leucine Rich Repeat Kinase 2 bound to GDP (from GMPPNP data)
Method: single particle / : Villagran A, Bodrug T

EMDB-72978: 
Leucine Rich Repeat LRRK2 (GDP data)
Method: single particle / : Villagran Suarez A, Bodrug T

EMDB-72982: 
Leucine Rich Repeat Kinase 2 active state (Apo state 3)
Method: single particle / : Villagran Suarez A, Bodrug T

EMDB-73484: 
Focused refinement map on N-terminal half of LRRK2 GMPPNP (active)-Resolved EM
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73485: 
Focused refinement map on N-terminal half of LRRK2 bound to GMPPNP (active)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73487: 
LRRK2 bound to GMP-PNP (inactive)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73491: 
Focused refinement map on LRRK2 bound to GMPPNP (inactive)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73492: 
Focused refinement map on LRRK2 bound to GMPPNP (inactive) Resolve EM
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73495: 
Focused refinement map of LRRK2 APO state 2
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73496: 
Focused refinement map of LRRK2 APO state 1
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

EMDB-73497: 
Focused map of LRRK2 bound to G10 (top)
Method: single particle / : Villagran AV, Bodrug T, Leschziner A

EMDB-73499: 
Focused map of LRRK2 bound to G10 (WD40-DARPin)
Method: single particle / : Villagran AV, Bodrug T, Leschziner A

EMDB-73501: 
Focused map of LRRK2 R1441C (active)
Method: single particle / : Villagran Suarez A, Bodrug T

EMDB-73502: 
Focused map of LRRK2 R1441C (active) ResolveEM
Method: single particle / : Villagran Suarez A, Bodrug T

PDB-9y7a: 
Leucine Rich Repeat Kinase 2 bound to GMP-PNP (inactive)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

PDB-9y7i: 
Leucine Rich Repeat Kinase 2 bound to GMP-PNP (active)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

PDB-9ybl: 
LRRK2 asymmetric dimer
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

PDB-9ybp: 
Leucine Rich Repeat Kinase 2 activate state (Apo ROC state 2)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

PDB-9yc8: 
Leucine Rich Repeat Kinase 2 activate state (Apo ROC state 1)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

PDB-9ycd: 
Leucine Rich Repeat Kinase 2 R1441C mutant (active)
Method: single particle / : Villagran Suarez A, Bodrug T, Leschziner A

PDB-9ygt: 
Leucine Rich Repeat Kinase 2 bound to GDP (from GMPPNP data)
Method: single particle / : Villagran A, Bodrug T

EMDB-70604: 
Full-length LRRK2 autoinhibited
Method: single particle / : Villagran-Suarez AC, Bodrug T

EMDB-70981: 
Full length LRRK2 bound to G10 DARPin
Method: single particle / : Villagran AV, Bodrug T, Leschziner A

EMDB-70982: 
Full-length LRRK2 autonhibited (flexible)
Method: single particle / : Villagran-Suarez A, Bodrug T, Alegrio-Louro J, Leschziner A

EMDB-71012: 
Full LRRK2 (R1441C mutant) after symmetry expansion
Method: single particle / : Villagran Suarez AC, Bodrug T

EMDB-72555: 
Full length LRRK2 after symmetry expansion
Method: single particle / : Villagran Suarez AC, Bodrug T

EMDB-72556: 
Full length LRRK2 (G2019S) after symmetry expansion
Method: single particle / : Villagran Suarez AC, Bodrug T

EMDB-73338: 
C-terminal LRRK2 bound to C12 DARPin
Method: single particle / : Sanz-Murillo M, Leschziner A

PDB-9om2: 
Full-length LRRK2 autoinhibited
Method: single particle / : Villagran-Suarez AC, Bodrug T

PDB-9oxh: 
Full length LRRK2 bound to G10 DARPin
Method: single particle / : Villagran AV, Bodrug T, Leschziner A

PDB-9oxi: 
Full-length LRRK2 autonhibited (flexible)
Method: single particle / : Villagran-Suarez A, Bodrug T

PDB-9oya: 
Full LRRK2 (R1441C mutant) after symmetry expansion
Method: single particle / : Villagran Suarez AC, Bodrug T

PDB-9y67: 
Full length LRRK2 after symmetry expansion
Method: single particle / : Villagran Suarez AC, Bodrug T

PDB-9y68: 
Full length LRRK2 (G2019S) after symmetry expansion
Method: single particle / : Villagran Suarez AC, Bodrug T

PDB-9yqk: 
C-terminal LRRK2 bound to C12 DARPin
Method: single particle / : Sanz-Murillo M, Leschziner A

EMDB-45592: 
13-pf microtubule from the LRRK2(I2020T) and MLi-2 dataset
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45593: 
Focused refinement map of WD40:ARM/ANK interface from LRRK2(I2020T) MLi-2 dataset
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45594: 
Full-length autoinhibited LRRK2(I2020T) co-polymerized with microtubules and MLi-2
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45595: 
Full-length autoinhibited LRRK2 on microtubules with MLi-2
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-45596: 
Full-length autoinhibited LRRK2 on microtubules with GZD-824
Method: subtomogram averaging / : Chen S, Leschziner AE, Villa E

EMDB-48263: 
Cryo-EM structure of Human NLRP3 complex with compound 1
Method: single particle / : Mammoliti O, Carbajo RJ, Perez-Benito L, Yu X, Prieri MLC, Bontempi L, Embrechts S, Paesmans I, Bassi M, Bhattacharya A, Roman SC, Hoog SD, Demin S, Gijsen HJM, Hache G, Jacobs T, Jerhaoui S, Leenaerts J, Lutter FH, Matico R, Oehlrich D, Perrier M, Ryabchuk P, Schepens W, Sharma S, Somers M, Suarez J, Surkyn M, Opdenbosch NV, Verhulst T, Bottelbergs A

EMDB-48288: 
Human NLRP3 complex with compound 2 in the closed hexamer
Method: single particle / : Mammoliti O, Carbajo RJ, Perez-Benito L, Yu X

EMDB-48289: 
Cryo-EM structure of Human NLRP3 complex with compound 3
Method: single particle / : Mammoliti O, Carbajo RJ, Perez-Benito L, Yu X, Prieri MLC, Bontempi L, Embrechts S, Paesmans I, Bassi M, Bhattacharya A, Roman SC, Hoog SD, Demin S, Gijsen HJM, Hache G, Jacobs T, Jerhaoui S, Leenaerts J, Lutter FH, Matico R, Oehlrich D, Perrier M, Ryabchuk P, Schepens W, Sharma S, Somers M, Suarez J, Surkyn M, Opdenbosch NV, Verhulst T, Bottelbergs A
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