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Showing all 28 items for (author: kappes & jc)

EMDB-45193:
V-Shaped, Channel Formed, T2a Nanobody Bound conformation of wild-type human CFTR (sharpened map from cryoSPARC non-uniform refinement)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-61553:
Asymmetric structure of cleaved HIV-1 Tri FPPR envelope glycoprotein trimer in amphipol-lipid nanodiscs (Tri FPPR.1)
Method: single particle / : Qi Y, Zhang S, Sodroski J, Mao Y

EMDB-61554:
Asymmetric structure of cleaved HIV-1 Tri FPPR envelope glycoprotein trimer in amphipol-lipid nanodiscs (Tri FPPR.2)
Method: single particle / : Qi Y, Zhang S, Sodroski J, Mao Y

EMDB-41895:
(N3Occluded Local CORE1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41896:
(N3Occluded Local ABC1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41898:
(N3Occluded Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41901:
(N3Occluded Composite Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41902:
(N3Occluded Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-42180:
(V17) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41717:
(N3Shifted Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-41719:
(N3Shifted Local CORE1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41722:
(N3Shifted Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41723:
(N3Shifted Local CORE2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41724:
(N3 Shifted Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41726:
(N3Shifted Composite Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-42177:
(Local CORE2) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-42178:
(Local ABC2) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-42179:
(Composite) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-41900:
(Local CORE2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41980:
(Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-41981:
(Local hNBD1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-43011:
Phosphorylated, ATP-bound, E1371Q human cystic fibrosis transmembrane conductance regulator (E1371Q-CFTR)
Method: single particle / : Gao X, Hwang T

EMDB-43014:
Phosphorylated, ATP-bound, inhibitor 172-bound E1371Q human cystic fibrosis transmembrane conductance regulator
Method: single particle / : Gao X, Hwang T

EMDB-28953:
Asymmetric structure of cleaved HIV-1 AD8 envelope glycoprotein trimer in styrene-maleic acid lipid nanoparticles
Method: single particle / : Wang K, Zhang S, Sodroski J, Mao Y

EMDB-28954:
Asymmetric structure of cleaved HIV-1 AE2 envelope glycoprotein trimer in styrene-maleic acid lipid nanoparticles (AE2.1)
Method: single particle / : Wang K, Zhang S, Sodroski J, Mao Y

EMDB-28955:
Asymmetric structure of cleaved HIV-1 AE2 envelope glycoprotein trimer in styrene-maleic acid lipid nanoparticles (AE2.2)
Method: single particle / : Wang K, Zhang S, Sodroski J, Mao Y

EMDB-23860:
Asymmetric structure of the uncleaved full-length HIV-1 envelope glycoprotein trimer in state U1
Method: single particle / : Zhang SJ, Wang KY, Wang WL, Sodroksi J, Mao YD

EMDB-23861:
Asymmetric structure of the uncleaved full-length HIV-1 envelope glycoprotein trimer in state U2
Method: single particle / : Zhang SJ, Wang KY, Wang WL, Sodroksi J, Mao YD

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