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Showing 1 - 50 of 357 items for (author: jia & hl)

EMDB-53206: 
GABA-A receptor a3b3g2 + a3NB83(PAM) + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

EMDB-53207: 
GABA-A receptor a3b3 (1:4) + a3NB77(silent) + b3Mb125 + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

EMDB-53208: 
GABA-A receptor a2b3 (1:4) + a2NB29(near-silent) + b3Mb125 + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

EMDB-53209: 
GABA-A receptor a2b3 (1:4) + a2NB16(silent) + b3Mb125 + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

EMDB-53212: 
GABA-A receptor a2b3 (1:4) + a2NB47(silent) + b3Mb125 + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

EMDB-53213: 
GABA-A receptor a2b3g2 + a2NB00(PAM) + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

EMDB-53214: 
GABA-A receptor a2b3g2 + a2NB04(silent) + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

EMDB-53215: 
GABA-A receptor a2b3g2 + a2NB25(inhibitor)
Method: single particle / : Miller PS, Gonzalez-Prada JE

EMDB-53216: 
GABA-A receptor a2b3 (1:4) + a2NB06(silent) + b3Mb125 + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

EMDB-56081: 
GABA-A receptor a3b3g2 + a3NB77 + bicuculline
Method: single particle / : Shang C, Nestorow SA, Miller PS

EMDB-56094: 
GABA-A receptor a3b3g2 + GABA-PRE + a3NB83
Method: single particle / : Shang C, Nestorow SA, Miller PS

EMDB-56109: 
GABA-A receptor a3b3g2 + a3NB77 + GABA
Method: single particle / : Shang C, Nestorow SA, Miller PS

PDB-9qjp: 
GABA-A receptor a3b3g2 + a3NB83(PAM) + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

PDB-9qjq: 
GABA-A receptor a3b3 (1:4) + a3NB77(silent) + b3Mb125 + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

PDB-9qjr: 
GABA-A receptor a2b3 (1:4) + a2NB29(near-silent) + b3Mb125 + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

PDB-9qjs: 
GABA-A receptor a2b3 (1:4) + a2NB16(silent) + b3Mb125 + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

PDB-9qjv: 
GABA-A receptor a2b3 (1:4) + a2NB47(silent) + b3Mb125 + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

PDB-9qjx: 
GABA-A receptor a2b3g2 + a2NB00(PAM) + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

PDB-9qjy: 
GABA-A receptor a2b3g2 + a2NB04(silent) + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

PDB-9qk0: 
GABA-A receptor a2b3g2 + a2NB25(inhibitor)
Method: single particle / : Miller PS, Gonzalez-Prada JE

PDB-9qk1: 
GABA-A receptor a2b3 (1:4) + a2NB06(silent) + b3Mb125 + GABA
Method: single particle / : Miller PS, Gonzalez-Prada JE

PDB-9tnb: 
GABA-A receptor a3b3g2 + a3NB77 + bicuculline
Method: single particle / : Shang C, Nestorow SA, Miller PS

PDB-9tns: 
GABA-A receptor a3b3g2 + GABA-PRE + a3NB83
Method: single particle / : Shang C, Nestorow SA, Miller PS

PDB-9tpq: 
GABA-A receptor a3b3g2 + a3NB77 + GABA
Method: single particle / : Shang C, Nestorow SA, Miller PS

EMDB-71756: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened consensus map from cryoSPARC non-uniform refinement)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71757: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened AHD1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71758: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened AHD2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71759: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened CORE1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71760: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened CORE2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71761: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened WalkerB1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71762: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened WalkerB2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71763: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened NBD1 plus T2a local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71764: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened NBD2 plus T2a local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71765: 
Alternative NBD1-binding geometry in channel-formed, ATP-bound, VX809-bound, T2a-nanobody-bound wild-type human CFTR (sharpened T2a plus T2a local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71698: 
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened AHD1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71709: 
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened AHD2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71710: 
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened CORE1 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71711: 
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened CORE2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71713: 
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened WalkerB2 local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-71714: 
V-shaped (channel-formed), ATP-bound, VX809-bound, T2a-nanobody-bound conformation of wild-type human CFTR (sharpened T2a local refinement map from cryoSPARC)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-62139: 
Structural and functional basis of antinociceptive action of conotoxin AoIA at the noradrenaline transporter
Method: single particle / : Zhang H, Harald S, Oliver B, Xu EH

PDB-9k6x: 
Structural and functional basis of antinociceptive action of conotoxin AoIA at the noradrenaline transporter
Method: single particle / : Zhang H, Harald S, Oliver B, Xu EH

EMDB-64402: 
Cryo-EM strucutre of CXCR4 complexed with agonist SDV1a
Method: single particle / : Jiao HZ, Sang XH, Huang ZW, Hu HL

EMDB-64403: 
Cryo-EM structure of CXCR4 complexed with agonist SDVX1
Method: single particle / : Jiao HZ, Sang XH, Huang ZW, Hu HL

EMDB-68747: 
Structure of CXCR4 in complex with a de-novo designed mini-protein antagonist
Method: single particle / : Banerjee R, Ganguly M, Banerjee N, Tiwari D, Muratspahic E, Baker D, Shukla AK

PDB-22xc: 
Structure of CXCR4 in complex with a de-novo designed mini-protein antagonist
Method: single particle / : Banerjee R, Ganguly M, Banerjee N, Tiwari D, Muratspahic E, Baker D, Shukla AK

EMDB-73949: 
Q23.MD39 in Complex with Fabs from antibodies CH01 and 35O22
Method: single particle / : Lin ZJ, Cui J, Du J, Habib R, Kulp D, Pallesen J

EMDB-73950: 
CryoEM map of CK52.1 in complex with Q23.V033GT
Method: single particle / : Lin ZJ, Cui J, Du J, Habib R, Kulp D, Pallesen J

PDB-9z9l: 
Q23.MD39 in Complex with Fabs from antibodies CH01 and 35O22
Method: single particle / : Lin ZJ, Cui J, Du J, Habib R, Kulp D, Pallesen J

EMDB-72977: 
Octopus sensory receptor CRT1 bound to Progesterone
Method: single particle / : Jiang H, Hibbs RE
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