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Showing 1 - 50 of 210 items for (author: grassucci & ra)

EMDB-41895:
(N3Occluded Local CORE1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41896:
(N3Occluded Local ABC1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41898:
(N3Occluded Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41901:
(N3Occluded Composite Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41902:
(N3Occluded Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-42180:
(V17) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41717:
(N3Shifted Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-41719:
(N3Shifted Local CORE1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41722:
(N3Shifted Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41723:
(N3Shifted Local CORE2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41724:
(N3 Shifted Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41726:
(N3Shifted Composite Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-42177:
(Local CORE2) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-42178:
(Local ABC2) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-42179:
(Composite) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-41900:
(Local CORE2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41980:
(Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-41981:
(Local hNBD1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-43811:
Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in nanodiscs
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43836:
Consensus map of human CaSR-miniGisq complex in nanodiscs
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43837:
Local refinement map of CaSR extracellular domain in nanodisc-reconstituted human CaSR-miniGisq complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43840:
Local refinement map of CaSR transmembrane domain in nanodisc-reconstituted human CaSR-miniGisq complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43841:
Local refinement map of G protein in nanodisc-reconstituted human CaSR-miniGisq complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43897:
Consensus map of human CaSR-miniGis complex in nanodiscs
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43898:
Local refinement map of CaSR extracellular domain in nanodisc-reconstituted human CaSR-miniGis complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43899:
Local refinement map of CaSR transmembrane domain in nanodisc-reconstituted human CaSR-miniGis complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43900:
Local refinement map of G protein in nanodisc-reconstituted human CaSR-miniGis complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43901:
Structure of human calcium-sensing receptor in complex with chimeric Gs (miniGis) protein in nanodiscs
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43904:
Consensus map of human CaSR-Gi3 complex in nanodiscs
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43905:
Local refinement map of CaSR extracellular domain in nanodisc-reconstituted human CaSR-Gi3 complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43906:
Local refinement map of CaSR transmembrane domain in nanodisc-reconstituted human CaSR-Gi3 complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43907:
Local refinement map of G protein in nanodisc-reconstituted human CaSR-Gi3 complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43908:
Structure of human calcium-sensing receptor in complex with Gi3 protein in nanodiscs
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43961:
Consensus map of human CaSR-miniGisq complex in detergent
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43962:
Local refinement map of CaSR extracellular domain (ECD) in detergent-solubilized human CaSR-miniGisq complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43963:
Local refinement map of CaSR transmembrane domain (TMD) in detergent-solubilized human CaSR-miniGisq complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43964:
Local refinement map of G protein in detergent-solubilized human CaSR-miniGisq complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43966:
Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in detergent
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43986:
Consensus map of human CaSR-miniGi1 complex in detergent
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43987:
Local refinement map of CaSR extracellular domain (ECD) in detergent-solubilized human CaSR-miniGi1 complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43988:
Local refinement map of CaSR transmembrane domain (TMD) in detergent-solubilized human CaSR-miniGi1 complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43989:
Local refinement map of G protein in detergent-solubilized human CaSR-miniGi1 complex
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-43990:
Structure of human calcium-sensing receptor in complex with Gi1 (miniGi1) protein in detergent
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

PDB-9asb:
Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in nanodiscs
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

PDB-9avg:
Structure of human calcium-sensing receptor in complex with chimeric Gs (miniGis) protein in nanodiscs
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

PDB-9avl:
Structure of human calcium-sensing receptor in complex with Gi3 protein in nanodiscs
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

PDB-9axf:
Structure of human calcium-sensing receptor in complex with chimeric Gq (miniGisq) protein in detergent
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

PDB-9ayf:
Structure of human calcium-sensing receptor in complex with Gi1 (miniGi1) protein in detergent
Method: single particle / : Zuo H, Park J, Frangaj A, Ye J, Lu G, Manning JJ, Asher WB, Lu Z, Hu G, Wang L, Mendez J, Eng E, Zhang Z, Lin X, Grasucci R, Hendrickson WA, Clarke OB, Javitch JA, Conigrave AD, Fan QR

EMDB-25143:
Structure of positive allosteric modulator-bound active human calcium-sensing receptor
Method: single particle / : Park J, Zuo H

EMDB-25144:
Structure of positive allosteric modulator-free active human calcium-sensing receptor
Method: single particle / : Park J, Zuo H

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