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Showing all 50 items for (author: fitzpatrick & awp)
![](data/emdb/media/28233/emdbimg.jpg)
EMDB-28233:
Cryo-EM structure of LRP2 at pH 7.5
Method: single particle / : Beenken A, Cerutti G, Brasch J, Fitzpatrick AW, Barasch J, Shapiro L
![](data/emdb/media/28241/emdbimg.jpg)
EMDB-28241:
Cryo-EM structure of LRP2 at pH 5.2
Method: single particle / : Beenken A, Cerutti G, Fitzpatrick AW, Barasch J, Shapiro L
![](data/emdb/media/28242/emdbimg.jpg)
EMDB-28242:
Local refinement map of LRP2 P1-P2 domains at pH 7.5
Method: single particle / : Beenken A, Shapiro L
![](data/emdb/media/28243/emdbimg.jpg)
EMDB-28243:
Local refinement of P3-P6 domains of LRP2 at pH 7.5
Method: single particle / : Beenken A, Shapiro L
![](data/emdb/media/28250/emdbimg.jpg)
EMDB-28250:
Local refinement of the P7 domain of LRP2 at pH 7.5
Method: single particle / : Beenken A, Shapiro L
![](data/emdb/media/28251/emdbimg.jpg)
EMDB-28251:
Local refinement of the R4 domain of LRP2 at pH 7.5
Method: single particle / : Beenken A, Shapiro L
![](data/emdb/media/28252/emdbimg.jpg)
EMDB-28252:
Local refinement of P8 domain of LRP2 at pH 7.5
Method: single particle / : Beenken A, Shapiro L
![](data/emdb/media/28253/emdbimg.jpg)
EMDB-28253:
Local refinement of P1-P2 domains of LRP2 at pH 5.2
Method: single particle / : Beenken A, Shapiro L
![](data/emdb/media/28258/emdbimg.jpg)
EMDB-28258:
Local refinement of P3-P6 domains of LRP2 at pH 5.2
Method: single particle / : Beenken A, Shapiro L
![](data/emdb/media/28260/emdbimg.jpg)
EMDB-28260:
Local refinement of P7 domain of LRP2 at pH 5.2
Method: single particle / : Beenken A, Shapiro L
![](data/emdb/media/28261/emdbimg.jpg)
EMDB-28261:
Local refinement of R3 domain of LRP2 at pH 5.2
Method: single particle / : Beenken A, Shapiro L
![](data/emdb/media/28265/emdbimg.jpg)
EMDB-28265:
Local refinement of P8 domain of LRP2 at pH 5.2
Method: single particle / : Beenken A, Shapiro L
![](data/emdb/media/26281/emdbimg.jpg)
EMDB-26281:
TMEM106B(120-254) singlet amyloid fibril from dementia with Lewy bodies (DLB).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26282/emdbimg.jpg)
EMDB-26282:
TMEM106B(120-254) doublet amyloid fibril from dementia with Lewy bodies (DLB).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26283/emdbimg.jpg)
EMDB-26283:
Low-resolution map of tau filament from progressive supranuclear palsy (PSP) case 3.
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26284/emdbimg.jpg)
EMDB-26284:
TMEM106B(120-254) singlet amyloid fibril from progressive supranuclear palsy (PSP) case 1.
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26285/emdbimg.jpg)
EMDB-26285:
TMEM106B(120-254) singlet amyloid fibril from progressive supranuclear palsy (PSP) case 2.
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26286/emdbimg.jpg)
EMDB-26286:
TMEM106B(120-254) doublet amyloid fibril from progressive supranuclear palsy (PSP) case 2.
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26268/emdbimg.jpg)
EMDB-26268:
High-resolution map of tau filament from progressive supranuclear palsy (PSP) case 1
Method: helical / : FItzpatrick AWP, Stowell MHB
![](data/emdb/media/26273/emdbimg.jpg)
EMDB-26273:
TMEM106B(120-254) protofilament from progressive supranuclear palsy (PSP) case 2
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA
![](data/emdb/media/26274/emdbimg.jpg)
EMDB-26274:
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA
![](data/emdb/media/26275/emdbimg.jpg)
EMDB-26275:
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 2)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA
![](data/emdb/media/26276/emdbimg.jpg)
EMDB-26276:
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA
![](data/emdb/media/26277/emdbimg.jpg)
EMDB-26277:
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type C (case 8)
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA
![](data/emdb/media/26278/emdbimg.jpg)
EMDB-26278:
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B case 2 (case 7).
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA
![](data/emdb/media/26279/emdbimg.jpg)
EMDB-26279:
TMEM106B(120-254) protofilament from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
Method: helical / : Fitzpatrick AWP, Stowell MHB, Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Mackenzie IRA
![](data/emdb/media/26287/snaps2.jpg)
EMDB-26287:
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type C (case 8).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26288/snaps2.jpg)
EMDB-26288:
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type B (case 6).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26289/snaps2.jpg)
EMDB-26289:
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 5).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26290/snaps2.jpg)
EMDB-26290:
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 4).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26291/snaps2.jpg)
EMDB-26291:
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 3).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26292/snaps2.jpg)
EMDB-26292:
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 3).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26293/snaps2.jpg)
EMDB-26293:
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 2).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26294/snaps2.jpg)
EMDB-26294:
TMEM106B(120-254) doublet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26295/snaps2.jpg)
EMDB-26295:
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (case 1).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/26296/snaps2.jpg)
EMDB-26296:
TMEM106B(120-254) singlet amyloid fibril from frontotemporal lobar degeneration with TDP-43 pathology (FTLD-TDP) type A (all cases combined).
Method: helical / : Chang A, Xiang X, Wang J, Lee C, Arakhamia T, Simjanoska M, Wang C, Carlomagno Y, Zhang G, Dhingra S, Thierry M, Perneel J, Heeman B, Forgrave LM, DeTure M, DeMarco ML, Cook CN, Rademakers R, Dickson D, Petrucelli L, Stowell MHB, Mackenzie IRA, Fitzpatrick AWP
![](data/emdb/media/21200/snaps2.jpg)
EMDB-21200:
Doublet Tau Fibril from Corticobasal Degeneration Human Brain Tissue
Method: helical / : Arakhamia T, Lee CE
![](data/emdb/media/21201/snaps2.jpg)
EMDB-21201:
Singlet Tau Fibril from Corticobasal Degeneration Human Brain Tissue
Method: helical / : Arakhamia T, Lee CE
![](data/emdb/media/21207/snaps2.jpg)
EMDB-21207:
Paired Helical Filament from Alzheimer's Disease Human Brain Tissue
Method: helical / : Arakhamia T, Lee CE
![](data/emdb/media/20333/snaps2.jpg)
EMDB-20333:
CryoEM Plasmodium falciparum M18 aspartyl aminopeptidase
Method: single particle / : Ho C, Zhou ZH
![](data/emdb/media/20334/snaps2.jpg)
EMDB-20334:
CryoEM Plasmodium falciparum glutamine synthetase
Method: single particle / : Ho CM, Zhou ZH
![](data/emdb/media/3741/snaps2.jpg)
EMDB-3741:
Paired helical filament in Alzheimer's disease brain
Method: helical / : Fitzpatrick AWP
![](data/emdb/media/3742/snaps2.jpg)
EMDB-3742:
Pronase-treated paired helical filament in Alzheimer's disease brain
Method: helical / : Fitzpatrick AWP, Falcon B, He S
![](data/emdb/media/3743/snaps2.jpg)
EMDB-3743:
Straight filament in Alzheimer's disease brain
Method: helical / : Fitzpatrick AWP, Falcon B, He S
![](data/emdb/media/3744/snaps2.jpg)
EMDB-3744:
Pronase-treated straight filament in Alzheimer's disease brain
Method: helical / : Fitzpatrick AWP, Falcon B, He S, Murzin AG, Murshudov G, Garringer HG, Crowther RA, Ghetti B, Goedert M, Scheres SHW
![](data/emdb/media/3652/snaps2.jpg)
EMDB-3652:
Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump
Method: single particle / : Fitzpatrick AWP, Llabres S
![](data/emdb/media/3653/snaps2.jpg)
EMDB-3653:
Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump-MacB section
Method: single particle / : Fitzpatrick AWP, Llabres S
![](data/emdb/media/5590/snaps2.jpg)
EMDB-5590:
Electron cryo-microscopy of a cross-beta amyloid fibril polymorph
Method: single particle / : Fitzpatrick AWP, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Muller S, MacPhee CE, Waudby CA, Mott HR, De-Simone A, Knowles TPJ, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM
![](data/emdb/media/2323/snaps2.jpg)
EMDB-2323:
Electron cryo-microscopy of a cross-beta amyloid fibril polymorph
Method: single particle / : Fitzpatrick AWP, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Muller S, MacPhee CE, Waudby CA, Mott HR, De-Simone A, Knowles TPJ, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM
![](data/emdb/media/2324/snaps2.jpg)
EMDB-2324:
Electron cryo-microscopy of a cross-beta amyloid fibril polymorph
Method: single particle / : Fitzpatrick AWP, Debelouchina GT, Bayro MJ, Clare DK, Caporini MA, Bajaj VS, Jaroniec CP, Wang L, Ladizhansky V, Muller S, MacPhee CE, Waudby CA, Mott HR, De-Simone A, Knowles TPJ, Saibil HR, Vendruscolo M, Orlova EV, Griffin RG, Dobson CM