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Showing all 38 items for (author: diberto & jf)

EMDB-44865:
Local refinement of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Kim K, Gumpper RH, Fay JF, Roth BL

EMDB-44866:
Global reconstruction of DRD2 bound to LSD in complex with a mini-GoA and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Kim K, Gumpper RH, Fay JF, Roth BL

EMDB-45616:
CryoEM Structure of HCA2 DREADD Gi1 in complex with FCH-2296413 (Local Refinement)
Method: single particle / : Krumm BE, Kang HJ, Diberto JF, Kapolka NJ, Gumpper RH, Olsen RHJ, Huang XP, Zhang S, Fay JF, Roth BL

EMDB-43797:
Local refinement of 5-HT2AR bound to 5-HT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43798:
Global reconstruction 5-HT2AR bound to 5-HT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43799:
Local refinement of 5-HT2AR bound to 2-bromo-LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43800:
Global reconstruction of 5-HT2AR bound to 2-bromo-LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43801:
Local refinement of 5-HT2AR bound to DMT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43802:
Global reconstruction of 5-HT2AR bound to DMT in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43803:
Local refinement of 5-HT2AR bound to LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43804:
Global reconstruction of 5-HT2AR bound to LSD in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43805:
Local refinement of 5-HT2AR bound to Mescaline in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43806:
Global reconstruction of 5-HT2AR bound to mescaline in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43807:
Local refinement of 5-HT2AR bound to psilocin in complex with a mini-Gq and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43808:
Global reconstruction of 5-HT2AR bound to psilocin in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43809:
Local refinement of 5-HT2AR bound to RS130-180 in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-43810:
Global reconstruction of 5-HT2AR bound to RS130-180 in complex with a mini-Gq protein and scFv16 obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Gumpper RH, Fay JF, Roth BL

EMDB-42538:
CryoEM Structure of HCA2-Gi1 in complex with MK-1903
Method: single particle / : Krumm BE, Kang HJ, Diberto JF, Kapolka NJ, Gumpper RH, Olsen RHJ, Huang XP, Zhang S, Fay JF, Roth BL

EMDB-42587:
CryoEM Structure of HCA2 DREADD Gi1 in complex with FCH-2296413
Method: single particle / : Krumm BE, Kang HJ, Diberto JF, Kapolka NJ, Gumpper RH, Olsen RHJ, Huang XP, Zhang S, Fay JF, Roth BL

EMDB-29301:
Neurotensin receptor allosterism revealed in complex with a biased allosteric modulator
Method: single particle / : Krumm BE, Diberto JF, Olsen RHJ, Kang H, Slocum ST, Zhang S, Strachan RT, Fay JF, Roth BL

EMDB-29302:
CryoEM structure of Go-coupled NTSR1 with a biased allosteric modulator
Method: single particle / : Krumm BE, DiBerto JF, Olsen RHJ, Kang H, Slocum ST, Zhang S, Strachan RT, Fay JF, Roth BL

EMDB-29303:
CryoEM structure of Go-coupled NTSR1
Method: single particle / : Krumm BE, DiBerto JF, Olsen RHJ, Kang H, Slocum ST, Zhang S, Strachan RT, Fay JF, Roth BL

EMDB-33241:
Cryo-EM Structure of Human Niacin Receptor HCA2-Gi protein complex
Method: single particle / : Yang Y, Kang HJ, Gao RG, Wang JJ, Han GW, DiBerto JF, Wu LJ, Tong JH, Qu L, Wu YR, Pileski R, Li XM, Zhang XC, Zhao SW, Kenakin T, Wang Q, Stevens RC, Peng W, Roth BL, Rao ZH, Liu ZJ

EMDB-28907:
Gi bound mu-opioid receptor in complex with beta-endorphin
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

EMDB-28908:
Gi bound mu-opioid receptor in complex with endomorphin
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

EMDB-28909:
Gi bound delta-opioid receptor in complex with deltorphin
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

EMDB-28911:
Gi bound kappa-opioid receptor in complex with dynorphin
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

EMDB-28912:
Gi bound nociceptin receptor in complex with nociceptin peptide
Method: single particle / : Wang Y, Zhuang Y, DiBerto JF, Zhou XE, Schmitz GP, Yuan Q, Jain MK, Liu W, Melcher K, Jiang Y, Roth BL, Xu HE

EMDB-26313:
C6-guano bound Mu Opioid Receptor-Gi Protein Complex
Method: single particle / : Wang H, Kobilka B

EMDB-25612:
CryoEM structure of mu-opioid receptor - Gi protein complex bound to mitragynine pseudoindoxyl (MP)
Method: single particle / : Seven AB, Qu Q, Robertson MJ, Wang H, Kobilka BK

EMDB-25613:
CryoEM structure of mu-opioid receptor - Gi protein complex bound to lofentanil (LFT)
Method: single particle / : Seven AB, Qu Q, Huang W, Robertson MJ, Kobilka BK, Skiniotis G

EMDB-24378:
5-HT2AR bound to a novel agonist in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Barros-Alvarez X, Kim K, Panova O

EMDB-26314:
C5guano-uOR-Gi-scFv16
Method: single particle / : Wang H, Qu Q

EMDB-24896:
CryoEM structure of Gq-coupled MRGPRX2 with peptide agonist Cortistatin-14
Method: single particle / : Cao C, Fay JF

EMDB-24897:
CryoEM structure of Gi-coupled MRGPRX2 with peptide agonist Cortistatin-14
Method: single particle / : Cao C, Fay JF

EMDB-24898:
CryoEM structure of Gq-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Method: single particle / : Cao C, Fay JF

EMDB-24899:
CryoEM structure of Gi-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573
Method: single particle / : Cao C, Fay JF

EMDB-24900:
CryoEM structure of Gq-coupled MRGPRX4 with small molecule agonist MS47134
Method: single particle / : Cao C, Fay JF

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Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

  • The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
  • EM Navigator can help to find cryo-EM structure data by both pioneers.

External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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