Author results

5XBM
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STRUCTURE OF SCARB2-JL2 COMPLEX
Descriptor:light chain of JL2, heavy chain of JL2, Lysosome membrane protein 2, ...
Authors:Zhang, X., Yang, P., Wang, N., Zhang, J., Li, J., Guo, H., Yin, X., Rao, Z., Wang, X., Zhang, L.
Deposit date:2017-03-20
Release date:2018-06-27
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection.
Protein Cell, 8, 2017
5ZMD
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CRYSTAL STRUCTURE OF FTO IN COMPLEX WITH M6DA MODIFIED SSDNA
Descriptor:Alpha-ketoglutarate-dependent dioxygenase FTO, DNA (5'-D(P*TP*CP*TP*(6MA)P*TP*AP*TP*CP*G)-3'), MANGANESE (II) ION, ...
Authors:Zhang, X., Wei, L.H., Luo, J., Xiao, Y., Liu, J., Zhang, W., Zhang, L., Jia, G.F.
Deposit date:2018-04-02
Release date:2019-04-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6AHF
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CRYOEM RECONSTRUCTION OF HSP104 N728A HEXAMER
Descriptor:Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Zhang, X., Zhang, L., Zhang, S.
Deposit date:2018-08-17
Release date:2019-02-13
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (6.78 Å)
Cite:Heat shock protein 104 (HSP104) chaperones soluble Tau via a mechanism distinct from its disaggregase activity.
J. Biol. Chem., 294, 2019
1NPU
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CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MURINE PD-1
Descriptor:Programmed cell death protein 1
Authors:Zhang, X., Schwartz, J.-C.D., Guo, X., Cao, E., Chen, L., Zhang, Z.-Y., Nathenson, S.G., Almo, S.C., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2003-01-20
Release date:2004-03-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural and functional analysis of the costimulatory receptor programmed death-1.
Immunity, 20, 2004
3J27
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CRYOEM STRUCTURE OF DENGUE VIRUS
Descriptor:Envelope protein E, Small envelope protein M, N-ACETYL-D-GLUCOSAMINE
Authors:Zhang, X., Ge, P., Yu, X., Brannan, J.M., Bi, G., Zhang, Q., Schein, S., Zhou, Z.H.
Deposit date:2012-09-26
Release date:2012-12-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the mature dengue virus at 3.5-A resolution.
Nat.Struct.Mol.Biol., 20, 2012
3J2P
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CRYOEM STRUCTURE OF DENGUE VIRUS ENVELOPE PROTEIN HETEROTETRAMER
Descriptor:Envelope protein E, Small envelope protein M, N-ACETYL-D-GLUCOSAMINE
Authors:Zhang, X., Ge, P., Yu, X., Brannan, J.M., Bi, G., Zhang, Q., Schein, S., Zhou, Z.H.
Deposit date:2012-11-30
Release date:2012-12-19
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the mature dengue virus at 3.5-A resolution.
Nat.Struct.Mol.Biol., 20, 2012
4GJT
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COMPLEX STRUCTURE OF NECTIN-4 BOUND TO MV-H
Descriptor:Hemagglutinin glycoprotein, Poliovirus receptor-related protein 4, N-ACETYL-D-GLUCOSAMINE
Authors:Zhang, X., Lu, G., Qi, J., Li, Y., He, Y., Xu, X., Shi, J., Zhang, C., Yan, J., Gao, G.F.
Deposit date:2012-08-10
Release date:2012-10-10
Last modified:2013-04-10
Method:X-RAY DIFFRACTION (3.1001 Å)
Cite:Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4
Nat.Struct.Mol.Biol., 20, 2013
3IYK
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BLUETONGUE VIRUS STRUCTURE REVEALS A SIALIC ACID BINDING DOMAIN, AMPHIPATHIC HELICES AND A CENTRAL COILED COIL IN THE OUTER CAPSID PROTEINS
Descriptor:VP5, VP2, 2-O-METHYL-5-N-ACETYL-ALPHA-D- NEURAMINIC ACID
Authors:Zhang, X., Boyce, M., Bhattacharya, B., Zhang, X., Schein, S., Roy, P., Zhou, Z.H.
Deposit date:2010-01-25
Release date:2010-04-07
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (7 Å)
Cite:Bluetongue virus coat protein VP2 contains sialic acid-binding domains, and VP5 resembles enveloped virus fusion proteins.
Proc.Natl.Acad.Sci.USA, 107, 2010
4KSY
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CRYSTAL STRUCTURE OF STING IN COMPLEX WITH CGAMP
Descriptor:Stimulator of interferon genes protein, cGAMP
Authors:Zhang, X., Chen, Z.J., Zhang, X.W.
Deposit date:2013-05-18
Release date:2013-06-12
Last modified:2018-06-27
Method:X-RAY DIFFRACTION (1.881 Å)
Cite:Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING.
Mol.Cell, 51, 2013
4O67
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HUMAN CYCLIC GMP-AMP SYNTHASE (CGAS) IN COMPLEX WITH GAMP
Descriptor:Cyclic GMP-AMP synthase, cGAMP, ZINC ION
Authors:Zhang, X., Chen, Z., Zhang, X.W., Chen, Z.J.
Deposit date:2013-12-20
Release date:2014-02-05
Last modified:2015-08-05
Method:X-RAY DIFFRACTION (2.444 Å)
Cite:The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
4O68
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STRUCTURE OF HUMAN CYCLIC GMP-AMP SYNTHASE (CGAS)
Descriptor:Cyclic GMP-AMP synthase, ZINC ION
Authors:Zhang, X., Chen, Z., Zhang, X.W., Chen, Z.J.
Deposit date:2013-12-20
Release date:2014-02-05
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (2.436 Å)
Cite:The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
4O69
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HUMAN CYCLIC GMP-AMP SYNTHASE (CGAS) IN COMPLEX WITH SULFATE ION
Descriptor:Cyclic GMP-AMP synthase, ZINC ION, SULFATE ION
Authors:Zhang, X., Chen, Z., Zhang, X.W., Chen, Z.J.
Deposit date:2013-12-20
Release date:2014-02-05
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (2.252 Å)
Cite:The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
4O6A
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MOUSE CYCLIC GMP-AMP SYNTHASE (CGAS) IN COMPLEX WITH DNA
Descriptor:Cyclic GMP-AMP synthase, DNA1, DNA2, ...
Authors:Zhang, X., Chen, Z., Zhang, X.W., Chen, Z.J.
Deposit date:2013-12-20
Release date:2014-02-05
Last modified:2014-03-05
Method:X-RAY DIFFRACTION (1.859 Å)
Cite:The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
5YB2
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CRYSTAL STRUCTURE OF LP-11/N44
Descriptor:Envelope glycoprotein, LP-11
Authors:Zhang, X., Wang, X., He, Y.
Deposit date:2017-09-03
Release date:2018-02-28
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket
Front Cell Infect Microbiol, 8, 2018
5YB3
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CRYSTAL STRUCTURE OF HP23L/N36
Descriptor:Envelope glycoprotein, HP23L
Authors:Zhang, X., Wang, X., He, Y.
Deposit date:2017-09-03
Release date:2018-02-28
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.043 Å)
Cite:Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket
Front Cell Infect Microbiol, 8, 2018
5YB4
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CRYSTAL STRUCTURE OF HP23LN36KR
Descriptor:N36KR, HP23L
Authors:Zhang, X., Wang, X., He, Y.
Deposit date:2017-09-03
Release date:2018-02-28
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket
Front Cell Infect Microbiol, 8, 2018
6ICZ
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CRYO-EM STRUCTURE OF A HUMAN POST-CATALYTIC SPLICEOSOME (P COMPLEX) AT 3.0 ANGSTROM
Descriptor:Protein mago nashi homolog 2, RNA-binding protein 8A, Eukaryotic initiation factor 4A-III, ...
Authors:Zhang, X., Zhan, X., Yan, C., Shi, Y.
Deposit date:2018-09-07
Release date:2019-03-13
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
6ID0
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CRYO-EM STRUCTURE OF A HUMAN INTRON LARIAT SPLICEOSOME PRIOR TO PRP43 LOADED (ILS1 COMPLEX) AT 2.9 ANGSTROM RESOLUTION
Descriptor:Pre-mRNA-processing-splicing factor 8, U5snRNA, 116 kDa U5 small nuclear ribonucleoprotein component, ...
Authors:Zhang, X., Zhan, X., Yan, C., Shi, Y.
Deposit date:2018-09-07
Release date:2019-03-13
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
6ID1
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CRYO-EM STRUCTURE OF A HUMAN INTRON LARIAT SPLICEOSOME AFTER PRP43 LOADED (ILS2 COMPLEX) AT 2.9 ANGSTROM RESOLUTION
Descriptor:Pre-mRNA-processing-splicing factor 8, U5snRNA, 116 kDa U5 small nuclear ribonucleoprotein component, ...
Authors:Zhang, X., Zhan, X., Yan, C., Shi, Y.
Deposit date:2018-09-07
Release date:2019-03-13
Last modified:2019-04-17
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
3J8G
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ELECTRON CRYO-MICROSCOPY STRUCTURE OF ENGA BOUND WITH THE 50S RIBOSOMAL SUBUNIT
Descriptor:5S rRNA, 23S rRNA, 50S ribosomal protein L28, ...
Authors:Zhang, X., Yan, K., Zhang, Y., Li, N., Ma, C., Li, Z., Zhang, Y., Feng, B., Liu, J., Sun, Y., Xu, Y., Lei, J., Gao, N.
Deposit date:2014-10-24
Release date:2014-11-26
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly
Nucleic Acids Res., 2014
1NUP
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NAMN ADENYLYLTRANSFERASE COMPLEX WITH NMN
Descriptor:FKSG76, SULFATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE
Authors:Zhang, X., Kurnasov, O.V., Karthikeyan, S., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2003-02-01
Release date:2003-06-03
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS
J.Biol.Chem., 278, 2003
1NUQ
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NAMN ADENYLYLTRANSFERASE COMPLEXED WITH NAAD
Descriptor:FKSG76, SULFATE ION, NICOTINIC ACID ADENINE DINUCLEOTIDE
Authors:Zhang, X., Kurnasov, O.V., Karthikeyan, S., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2003-02-01
Release date:2003-06-03
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS
J.Biol.Chem., 278, 2003
1NUR
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NAMN ADENYLYLTRANSFERASE
Descriptor:FKSG76, SULFATE ION
Authors:Zhang, X., Kurnasov, O.V., Karthikeyan, S., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2003-02-01
Release date:2003-06-03
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS
J.Biol.Chem., 278, 2003
1NUS
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NAMN ADENYLYLTRANSFERASE COMPLEXED WITH ATP ANALOG AND NMN
Descriptor:FKSG76, SULFATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, ...
Authors:Zhang, X., Kurnasov, O.V., Karthikeyan, S., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2003-02-01
Release date:2003-06-03
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS
J.Biol.Chem., 278, 2003
1NUT
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CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NAMN ADENYLYLTRANSFERASE COMPLEXED WITH ATP ANALOG
Descriptor:FKSG76, SULFATE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER
Authors:Zhang, X., Kurnasov, O.V., Karthikeyan, S., Grishin, N.V., Osterman, A.L., Zhang, H.
Deposit date:2003-02-01
Release date:2003-06-03
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS
J.Biol.Chem., 278, 2003