5XBM | | STRUCTURE OF SCARB2-JL2 COMPLEX | | Descriptor: | light chain of JL2, heavy chain of JL2, Lysosome membrane protein 2, ... | | Authors: | Zhang, X., Yang, P., Wang, N., Zhang, J., Li, J., Guo, H., Yin, X., Rao, Z., Wang, X., Zhang, L. | | Deposit date: | 2017-03-20 | | Release date: | 2018-06-27 | | Method: | X-RAY DIFFRACTION (3.501 Å) | | Cite: | The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection.
Protein Cell, 8, 2017
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1NPU | | CRYSTAL STRUCTURE OF THE EXTRACELLULAR DOMAIN OF MURINE PD-1 | | Descriptor: | Programmed cell death protein 1 | | Authors: | Zhang, X., Schwartz, J.-C.D., Guo, X., Cao, E., Chen, L., Zhang, Z.-Y., Nathenson, S.G., Almo, S.C., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC) | | Deposit date: | 2003-01-20 | | Release date: | 2004-03-23 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and functional analysis of the costimulatory receptor programmed death-1.
Immunity, 20, 2004
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3J27 | | CRYOEM STRUCTURE OF DENGUE VIRUS | | Descriptor: | Envelope protein E, Small envelope protein M, N-ACETYL-D-GLUCOSAMINE | | Authors: | Zhang, X., Ge, P., Yu, X., Brannan, J.M., Bi, G., Zhang, Q., Schein, S., Zhou, Z.H. | | Deposit date: | 2012-09-26 | | Release date: | 2012-12-19 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of the mature dengue virus at 3.5-A resolution.
Nat.Struct.Mol.Biol., 20, 2012
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3J2P | | CRYOEM STRUCTURE OF DENGUE VIRUS ENVELOPE PROTEIN HETEROTETRAMER | | Descriptor: | Envelope protein E, Small envelope protein M, N-ACETYL-D-GLUCOSAMINE | | Authors: | Zhang, X., Ge, P., Yu, X., Brannan, J.M., Bi, G., Zhang, Q., Schein, S., Zhou, Z.H. | | Deposit date: | 2012-11-30 | | Release date: | 2012-12-19 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Cryo-EM structure of the mature dengue virus at 3.5-A resolution.
Nat.Struct.Mol.Biol., 20, 2012
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4GJT | | COMPLEX STRUCTURE OF NECTIN-4 BOUND TO MV-H | | Descriptor: | Hemagglutinin glycoprotein, Poliovirus receptor-related protein 4, N-ACETYL-D-GLUCOSAMINE | | Authors: | Zhang, X., Lu, G., Qi, J., Li, Y., He, Y., Xu, X., Shi, J., Zhang, C., Yan, J., Gao, G.F. | | Deposit date: | 2012-08-10 | | Release date: | 2012-10-10 | | Last modified: | 2013-04-10 | | Method: | X-RAY DIFFRACTION (3.1001 Å) | | Cite: | Structure of measles virus hemagglutinin bound to its epithelial receptor nectin-4
Nat.Struct.Mol.Biol., 20, 2013
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5ZMD | | CRYSTAL STRUCTURE OF FTO IN COMPLEX WITH M6DA MODIFIED SSDNA | | Descriptor: | Alpha-ketoglutarate-dependent dioxygenase FTO, DNA (5'-D(P*TP*CP*TP*(6MA)P*TP*AP*TP*CP*G)-3'), MANGANESE (II) ION, ... | | Authors: | Zhang, X., Wei, L.H., Luo, J., Xiao, Y., Liu, J., Zhang, W., Zhang, L., Jia, G.F. | | Deposit date: | 2018-04-02 | | Release date: | 2019-04-10 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6AHF | | CRYOEM RECONSTRUCTION OF HSP104 N728A HEXAMER | | Descriptor: | Heat shock protein 104, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | | Authors: | Zhang, X., Zhang, L., Zhang, S. | | Deposit date: | 2018-08-17 | | Release date: | 2019-02-13 | | Last modified: | 2019-04-10 | | Method: | ELECTRON MICROSCOPY (6.78 Å) | | Cite: | Heat shock protein 104 (HSP104) chaperones soluble Tau via a mechanism distinct from its disaggregase activity.
J. Biol. Chem., 294, 2019
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3IYK | | BLUETONGUE VIRUS STRUCTURE REVEALS A SIALIC ACID BINDING DOMAIN, AMPHIPATHIC HELICES AND A CENTRAL COILED COIL IN THE OUTER CAPSID PROTEINS | | Descriptor: | VP5, VP2, 2-O-METHYL-5-N-ACETYL-ALPHA-D- NEURAMINIC ACID | | Authors: | Zhang, X., Boyce, M., Bhattacharya, B., Zhang, X., Schein, S., Roy, P., Zhou, Z.H. | | Deposit date: | 2010-01-25 | | Release date: | 2010-04-07 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (7 Å) | | Cite: | Bluetongue virus coat protein VP2 contains sialic acid-binding domains, and VP5 resembles enveloped virus fusion proteins.
Proc.Natl.Acad.Sci.USA, 107, 2010
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4KSY | |
4O67 | | HUMAN CYCLIC GMP-AMP SYNTHASE (CGAS) IN COMPLEX WITH GAMP | | Descriptor: | Cyclic GMP-AMP synthase, cGAMP, ZINC ION | | Authors: | Zhang, X., Chen, Z., Zhang, X.W., Chen, Z.J. | | Deposit date: | 2013-12-20 | | Release date: | 2014-02-05 | | Last modified: | 2015-08-05 | | Method: | X-RAY DIFFRACTION (2.444 Å) | | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
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4O68 | | STRUCTURE OF HUMAN CYCLIC GMP-AMP SYNTHASE (CGAS) | | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | | Authors: | Zhang, X., Chen, Z., Zhang, X.W., Chen, Z.J. | | Deposit date: | 2013-12-20 | | Release date: | 2014-02-05 | | Last modified: | 2014-03-05 | | Method: | X-RAY DIFFRACTION (2.436 Å) | | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
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4O69 | | HUMAN CYCLIC GMP-AMP SYNTHASE (CGAS) IN COMPLEX WITH SULFATE ION | | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION, SULFATE ION | | Authors: | Zhang, X., Chen, Z., Zhang, X.W., Chen, Z.J. | | Deposit date: | 2013-12-20 | | Release date: | 2014-02-05 | | Last modified: | 2014-03-05 | | Method: | X-RAY DIFFRACTION (2.252 Å) | | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
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4O6A | | MOUSE CYCLIC GMP-AMP SYNTHASE (CGAS) IN COMPLEX WITH DNA | | Descriptor: | Cyclic GMP-AMP synthase, DNA1, DNA2, ... | | Authors: | Zhang, X., Chen, Z., Zhang, X.W., Chen, Z.J. | | Deposit date: | 2013-12-20 | | Release date: | 2014-02-05 | | Last modified: | 2014-03-05 | | Method: | X-RAY DIFFRACTION (1.859 Å) | | Cite: | The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
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5YB2 | | CRYSTAL STRUCTURE OF LP-11/N44 | | Descriptor: | Envelope glycoprotein, LP-11 | | Authors: | Zhang, X., Wang, X., He, Y. | | Deposit date: | 2017-09-03 | | Release date: | 2018-02-28 | | Last modified: | 2018-03-28 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket
Front Cell Infect Microbiol, 8, 2018
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5YB3 | | CRYSTAL STRUCTURE OF HP23L/N36 | | Descriptor: | Envelope glycoprotein, HP23L | | Authors: | Zhang, X., Wang, X., He, Y. | | Deposit date: | 2017-09-03 | | Release date: | 2018-02-28 | | Last modified: | 2018-03-28 | | Method: | X-RAY DIFFRACTION (2.043 Å) | | Cite: | Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket
Front Cell Infect Microbiol, 8, 2018
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5YB4 | | CRYSTAL STRUCTURE OF HP23LN36KR | | Descriptor: | N36KR, HP23L | | Authors: | Zhang, X., Wang, X., He, Y. | | Deposit date: | 2017-09-03 | | Release date: | 2018-02-28 | | Last modified: | 2018-03-28 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket
Front Cell Infect Microbiol, 8, 2018
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6ICZ | | CRYO-EM STRUCTURE OF A HUMAN POST-CATALYTIC SPLICEOSOME (P COMPLEX) AT 3.0 ANGSTROM | | Descriptor: | Protein mago nashi homolog 2, RNA-binding protein 8A, Eukaryotic initiation factor 4A-III, ... | | Authors: | Zhang, X., Zhan, X., Yan, C., Shi, Y. | | Deposit date: | 2018-09-07 | | Release date: | 2019-03-13 | | Last modified: | 2019-04-17 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
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6ID0 | | CRYO-EM STRUCTURE OF A HUMAN INTRON LARIAT SPLICEOSOME PRIOR TO PRP43 LOADED (ILS1 COMPLEX) AT 2.9 ANGSTROM RESOLUTION | | Descriptor: | Pre-mRNA-processing-splicing factor 8, U5snRNA, 116 kDa U5 small nuclear ribonucleoprotein component, ... | | Authors: | Zhang, X., Zhan, X., Yan, C., Shi, Y. | | Deposit date: | 2018-09-07 | | Release date: | 2019-03-13 | | Last modified: | 2019-04-17 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
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6ID1 | | CRYO-EM STRUCTURE OF A HUMAN INTRON LARIAT SPLICEOSOME AFTER PRP43 LOADED (ILS2 COMPLEX) AT 2.9 ANGSTROM RESOLUTION | | Descriptor: | Pre-mRNA-processing-splicing factor 8, U5snRNA, 116 kDa U5 small nuclear ribonucleoprotein component, ... | | Authors: | Zhang, X., Zhan, X., Yan, C., Shi, Y. | | Deposit date: | 2018-09-07 | | Release date: | 2019-03-13 | | Last modified: | 2019-04-17 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Structures of the human spliceosomes before and after release of the ligated exon.
Cell Res., 29, 2019
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3J8G | | ELECTRON CRYO-MICROSCOPY STRUCTURE OF ENGA BOUND WITH THE 50S RIBOSOMAL SUBUNIT | | Descriptor: | 5S rRNA, 23S rRNA, 50S ribosomal protein L28, ... | | Authors: | Zhang, X., Yan, K., Zhang, Y., Li, N., Ma, C., Li, Z., Zhang, Y., Feng, B., Liu, J., Sun, Y., Xu, Y., Lei, J., Gao, N. | | Deposit date: | 2014-10-24 | | Release date: | 2014-11-26 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (5 Å) | | Cite: | Structural insights into the function of a unique tandem GTPase EngA in bacterial ribosome assembly
Nucleic Acids Res., 2014
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1NUP | | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NAMN ADENYLYLTRANSFERASE COMPLEX WITH NMN | | Descriptor: | FKSG76, SULFATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE | | Authors: | Zhang, X., Kurnasov, O.V., Karthikeyan, S., Grishin, N.V., Osterman, A.L., Zhang, H. | | Deposit date: | 2003-02-01 | | Release date: | 2003-06-03 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN
ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS
J.Biol.Chem., 278, 2003
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1NUQ | | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NAMN ADENYLYLTRANSFERASE COMPLEXED WITH NAAD | | Descriptor: | FKSG76, SULFATE ION, NICOTINIC ACID ADENINE DINUCLEOTIDE | | Authors: | Zhang, X., Kurnasov, O.V., Karthikeyan, S., Grishin, N.V., Osterman, A.L., Zhang, H. | | Deposit date: | 2003-02-01 | | Release date: | 2003-06-03 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN
ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS
J.Biol.Chem., 278, 2003
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1NUR | | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NAMN ADENYLYLTRANSFERASE | | Descriptor: | FKSG76, SULFATE ION | | Authors: | Zhang, X., Kurnasov, O.V., Karthikeyan, S., Grishin, N.V., Osterman, A.L., Zhang, H. | | Deposit date: | 2003-02-01 | | Release date: | 2003-06-03 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN
ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS
J.Biol.Chem., 278, 2003
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1NUS | | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NAMN ADENYLYLTRANSFERASE COMPLEXED WITH ATP ANALOG AND NMN | | Descriptor: | FKSG76, SULFATE ION, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, ... | | Authors: | Zhang, X., Kurnasov, O.V., Karthikeyan, S., Grishin, N.V., Osterman, A.L., Zhang, H. | | Deposit date: | 2003-02-01 | | Release date: | 2003-06-03 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN
ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS
J.Biol.Chem., 278, 2003
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1NUT | | CRYSTAL STRUCTURE OF HUMAN CYTOSOLIC NMN/NAMN ADENYLYLTRANSFERASE COMPLEXED WITH ATP ANALOG | | Descriptor: | FKSG76, SULFATE ION, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | | Authors: | Zhang, X., Kurnasov, O.V., Karthikeyan, S., Grishin, N.V., Osterman, A.L., Zhang, H. | | Deposit date: | 2003-02-01 | | Release date: | 2003-06-03 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | STRUCTURAL CHARACTERIZATION OF A HUMAN CYTOSOLIC NMN/NaMN
ADENYLYLTRANSFERASE AND IMPLICATION IN HUMAN NAD BIOSYNTHESIS
J.Biol.Chem., 278, 2003
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