1K9O | | CRYSTAL STRUCTURE OF MICHAELIS SERPIN-TRYPSIN COMPLEX | | Descriptor: | ALASERPIN, TRYPSIN II ANIONIC | | Authors: | Ye, S., Cech, A.L., Belmares, R., Bergstrom, R.C., Tong, Y., Corey, D.R., Kanost, M.R., Goldsmith, E.J. | | Deposit date: | 2001-10-29 | | Release date: | 2001-11-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The structure of a Michaelis serpin-protease complex.
Nat.Struct.Biol., 8, 2001
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1P74 | | CRYSTAL STRUCTURE OF SHIKIMATE DEHYDROGENASE (AROE) FROM HAEMOPHILUS INFLUENZAE | | Descriptor: | Shikimate 5-dehydrogenase | | Authors: | Ye, S., von Delft, F., Brooun, A., Knuth, M.W., Swanson, R.V., McRee, D.E. | | Deposit date: | 2003-04-30 | | Release date: | 2003-08-12 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The crystal structure of shikimate dehydrogenase (AroE) reveals a unique NADPH binding mode
J.Bacteriol., 185, 2003
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1P77 | | CRYSTAL STRUCTURE OF SHIKIMATE DEHYDROGENASE (AROE) FROM HAEMOPHILUS INFLUENZAE | | Descriptor: | Shikimate 5-dehydrogenase, ACETATE ION, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE | | Authors: | Ye, S., von Delft, F., Brooun, A., Knuth, M.W., Swanson, R.V., McRee, D.E. | | Deposit date: | 2003-04-30 | | Release date: | 2003-08-12 | | Last modified: | 2018-01-31 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | The crystal structure of shikimate dehydrogenase (AroE) reveals a unique NADPH binding mode
J.Bacteriol., 185, 2003
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1QQK | | THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7 (KERATINOCYTE GROWTH FACTOR) | | Descriptor: | FIBROBLAST GROWTH FACTOR 7 | | Authors: | Ye, S., Luo, Y., Pelletier, H., McKeehan, W.L. | | Deposit date: | 1999-06-07 | | Release date: | 2000-01-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
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1QQL | | THE CRYSTAL STRUCTURE OF FIBROBLAST GROWTH FACTOR 7/1 CHIMERA | | Descriptor: | FIBROBLAST GROWTH FACTOR 7/1 CHIMERA | | Authors: | Ye, S., Luo, Y., Pelletier, H., McKeehan, W.L. | | Deposit date: | 1999-06-07 | | Release date: | 2000-01-14 | | Last modified: | 2017-08-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for interaction of FGF-1, FGF-2, and FGF-7 with different heparan sulfate motifs.
Biochemistry, 40, 2001
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1R8J | |
2FY8 | |
2IC1 | | CRYSTAL STRUCTURE OF HUMAN CYSTEINE DIOXYGENASE IN COMPLEX WITH SUBSTRATE CYSTEINE | | Descriptor: | Cysteine dioxygenase type 1, FE (II) ION, CYSTEINE | | Authors: | Ye, S., Wu, X., Wei, L., Tang, D., Sun, P., Rao, Z. | | Deposit date: | 2006-09-12 | | Release date: | 2006-12-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | An Insight into the Mechanism of Human Cysteine Dioxygenase: KEY ROLES OF THE THIOETHER-BONDED TYROSINE-CYSTEINE COFACTOR.
J.Biol.Chem., 282, 2007
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3LDC | | HIGH RESOLUTION OPEN MTHK PORE STRUCTURE CRYSTALLIZED IN 100 MM K+ | | Descriptor: | Calcium-gated potassium channel mthK, POTASSIUM ION | | Authors: | Ye, S. | | Deposit date: | 2010-01-12 | | Release date: | 2010-08-11 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Novel insights into K(+) selectivity from high-resolution structures of an open K(+) channel pore.
Nat.Struct.Mol.Biol., 17, 2010
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3LDD | |
3LDE | |
4Y0Y | | TRYPSIN IN COMPLEX WITH WITH BPTI | | Descriptor: | Cationic trypsin, Pancreatic trypsin inhibitor, SULFATE ION, ... | | Authors: | Loll, B., Ye, S., Berger, A.A., Muelow, U., Alings, C., Wahl, M.C., Koksch, B. | | Deposit date: | 2015-02-06 | | Release date: | 2015-06-24 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Fluorine teams up with water to restore inhibitor activity to mutant BPTI.
Chem Sci, 6, 2015
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4Y0Z | | TRYPSIN IN COMPLEX WITH WITH BPTI MUTANT AMINOBUTYRIC ACID | | Descriptor: | Cationic trypsin, Pancreatic trypsin inhibitor, SULFATE ION, ... | | Authors: | Loll, B., Ye, S., Berger, A.A., Muelow, U., Alings, C., Wahl, M.C., Koksch, B. | | Deposit date: | 2015-02-06 | | Release date: | 2015-06-24 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | Fluorine teams up with water to restore inhibitor activity to mutant BPTI.
Chem Sci, 6, 2015
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4Y10 | | TRYPSIN IN COMPLEX WITH WITH BPTI MUTANT (2S)-2-AMINO-4,4-DIFLUOROBUTANOIC ACID | | Descriptor: | Cationic trypsin, Pancreatic trypsin inhibitor, SULFATE ION, ... | | Authors: | Loll, B., Ye, S., Berger, A.A., Muelow, U., Alings, C., Wahl, M.C., Koksch, B. | | Deposit date: | 2015-02-06 | | Release date: | 2015-06-24 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (1.37 Å) | | Cite: | Fluorine teams up with water to restore inhibitor activity to mutant BPTI.
Chem Sci, 6, 2015
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4Y11 | | TRYPSIN IN COMPLEX WITH WITH BPTI MUTANT (2S)-2-AMINO-4,4,4-TRIFLUOROBUTANOIC ACID | | Descriptor: | Cationic trypsin, Pancreatic trypsin inhibitor, SULFATE ION, ... | | Authors: | Loll, B., Ye, S., Berger, A.A., Muelow, U., Alings, C., Wahl, M.C., Koksch, B. | | Deposit date: | 2015-02-06 | | Release date: | 2015-06-24 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Fluorine teams up with water to restore inhibitor activity to mutant BPTI.
Chem Sci, 6, 2015
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5Y56 | | FC MUTANT (K392D/K409D/D399K) | | Descriptor: | Immunoglobulin gamma-1 heavy chain, N-ACETYL-D-GLUCOSAMINE, BETA-L-FUCOSE, ... | | Authors: | Ye, S., Xu, T., Yu, J., Wang, X., Xu, T., Jin, Q., Duan, J., Wu, J., Wu, H. | | Deposit date: | 2017-08-07 | | Release date: | 2017-09-13 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2.653 Å) | | Cite: | A rational approach to enhancing antibody Fc homodimer formation for robust production of antibody mixture in a single cell line
J. Biol. Chem., 292, 2017
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5H0N | |
1J04 | | STRUCTURAL MECHANISM OF ENZYME MISTARGETING IN HEREDITARY KIDNEY STONE DISEASE IN VITRO | | Descriptor: | alanine--glyoxylate aminotransferase, (AMINOOXY)ACETIC ACID, GLYCEROL | | Authors: | Zhang, X., Djordjevic, S., Bartlam, M., Ye, S., Rao, Z., Danpure, C.J. | | Deposit date: | 2002-10-30 | | Release date: | 2003-11-11 | | Last modified: | 2018-07-25 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural implications of a G170R mutation of alanine:glyoxylate aminotransferase that is associated with peroxisome-to-mitochondrion mistargeting.
Acta Crystallogr.,Sect.F, 66, 2010
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1ZD7 | | 1.7 ANGSTROM CRYSTAL STRUCTURE OF POST-SPLICING FORM OF A DNAE INTEIN FROM SYNECHOCYSTIS SP. PCC 6803 | | Descriptor: | DNA polymerase III alpha subunit, SULFATE ION | | Authors: | Sun, P., Ye, S., Ferrandon, S., Evans, T.C., Xu, M.Q., Rao, Z. | | Deposit date: | 2005-04-14 | | Release date: | 2006-01-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structures of an intein from the split dnaE gene of Synechocystis sp. PCC6803 reveal the catalytic model without the penultimate histidine and the mechanism of zinc ion inhibition of protein splicing
J.Mol.Biol., 353, 2005
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1ZDE | | 1.95 ANGSTROM CRYSTAL STRUCTURE OF A DNAE INTEIN PRECURSOR FROM SYNECHOCYSTIS SP. PCC 6803 | | Descriptor: | DNA polymerase III alpha subunit, ZINC ION, CALCIUM ION | | Authors: | Sun, P., Ye, S., Ferrandon, S., Evans, T.C., Xu, M.Q., Rao, Z. | | Deposit date: | 2005-04-14 | | Release date: | 2006-01-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Crystal structures of an intein from the split dnaE gene of Synechocystis sp. PCC6803 reveal the catalytic model without the penultimate histidine and the mechanism of zinc ion inhibition of protein splicing
J.Mol.Biol., 353, 2005
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3EB7 | | CRYSTAL STRUCTURE OF INSECTICIDAL DELTA-ENDOTOXIN CRY8EA1 FROM BACILLUS THURINGIENSIS AT 2.2 ANGSTROMS RESOLUTION | | Descriptor: | Insecticidal Delta-Endotoxin Cry8Ea1, SULFATE ION, ACETATE ION | | Authors: | Guo, S., Ye, S., Song, F., Zhang, J., Wei, L., Shu, C.L. | | Deposit date: | 2008-08-27 | | Release date: | 2008-09-16 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal structure of Bacillus thuringiensis Cry8Ea1: An insecticidal toxin toxic to underground pests, the larvae of Holotrichia parallela.
J.Struct.Biol., 168, 2009
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3JU5 | | CRYSTAL STRUCTURE OF DIMERIC ARGININE KINASE AT 1.75-A RESOLUTION | | Descriptor: | Arginine kinase, MAGNESIUM ION | | Authors: | Wu, X., Ye, S., Guo, S., Yan, W., Bartlam, M., Rao, Z. | | Deposit date: | 2009-09-14 | | Release date: | 2009-09-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity
Faseb J., 24, 2010
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3JU6 | | CRYSTAL STRUCTURE OF DIMERIC ARGININE KINASE IN COMPLEX WITH AMPPNP AND ARGININE | | Descriptor: | Arginine kinase, ARGININE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Wu, X., Ye, S., Guo, S., Yan, W., Bartlam, M., Rao, Z. | | Deposit date: | 2009-09-14 | | Release date: | 2009-09-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural basis for a reciprocating mechanism of negative cooperativity in dimeric phosphagen kinase activity
Faseb J., 24, 2010
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4NJL | | CRYSTAL STRUCTURE OF MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS S2 PROTEIN FUSION CORE | | Descriptor: | S protein, TRIETHYLENE GLYCOL | | Authors: | Zhu, Y., Lu, L., Qin, L., Ye, S., Jiang, S., Zhang, R. | | Deposit date: | 2013-11-10 | | Release date: | 2014-02-19 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor.
Nat Commun, 5, 2014
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4PV7 | | COCRYSTAL STRUCTURE OF DIPEPTIDYL-PEPTIDASE 4 WITH AN INDOLE SCAFFOLD INHIBITOR | | Descriptor: | Dipeptidyl peptidase 4 soluble form, 1-[2-(2,4-dichlorophenyl)-1-(methylsulfonyl)-1H-indol-3-yl]methanamine | | Authors: | Xiao, P., Guo, R., Huang, S., Cui, H., Ye, S., Zhang, Z. | | Deposit date: | 2014-03-15 | | Release date: | 2015-03-18 | | Method: | X-RAY DIFFRACTION (3.24 Å) | | Cite: | Discovery of dipeptidyl peptidase IV (DPP4) inhibitors based on a novel indole scaffold
Chin.Chem.Lett., 25, 2014
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