3CUN
 
 | Aminoacyl-tRNA synthetase ribozyme | Descriptor: | COBALT (II) ION, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Xiao, H, Murakami, H, Suga, H, Ferre-D'Amare, A.R. | Deposit date: | 2008-04-16 | Release date: | 2008-06-24 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis of specific tRNA aminoacylation by a small in vitro selected ribozyme. Nature, 454, 2008
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9LR9
 
 | Local reconstruction of bovine adenovirus type 3 capsid | Descriptor: | Hexon protein, PIX, PV, ... | Authors: | Xiao, H, Liu, H.R. | Deposit date: | 2025-01-30 | Release date: | 2025-06-04 | Last modified: | 2025-06-11 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural Insights into Minor and Core Proteins of Bovine Adenovirus 3: Bridging Capsid and Genomic Core. J.Mol.Biol., 437, 2025
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9LTA
 
 | Crystal Structure of Compound SKLB-D18 with MAPK7 (ERK5) | Descriptor: | 4-[5-chloranyl-2-[[3-[(dimethylamino)methyl]phenyl]amino]pyrimidin-4-yl]-~{N}-morpholin-4-yl-thiophene-2-carboxamide, Mitogen-activated protein kinase 7 | Authors: | Xiao, H, Sun, Q. | Deposit date: | 2025-02-05 | Release date: | 2025-04-02 | Method: | X-RAY DIFFRACTION (2.33 Å) | Cite: | A first-in-class selective inhibitor of ERK1/2 and ERK5 overcomes drug resistance with a single-molecule strategy. Signal Transduct Target Ther, 10, 2025
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9LNR
 
 | Crystal structure of SKLB-D18 with ERK2 | Descriptor: | 4-[5-chloranyl-2-[[3-[(dimethylamino)methyl]phenyl]amino]pyrimidin-4-yl]-~{N}-morpholin-4-yl-thiophene-2-carboxamide, GLYCEROL, Mitogen-activated protein kinase 1 | Authors: | Xiao, H, Sun, Q. | Deposit date: | 2025-01-21 | Release date: | 2025-04-02 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A first-in-class selective inhibitor of ERK1/2 and ERK5 overcomes drug resistance with a single-molecule strategy. Signal Transduct Target Ther, 10, 2025
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4ZJ1
 
 | Crystal Structure of p-acrylamido-phenylalanine modified TEM1 beta-lactamase from Escherichia coli : V216AcrF mutant | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-lactamase TEM, DI(HYDROXYETHYL)ETHER, ... | Authors: | Xiao, H, Nasertorabi, F, Choi, S, Han, G.W, Reed, S.A, Stevens, R.C, Schultz, P.G. | Deposit date: | 2015-04-28 | Release date: | 2015-05-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Exploring the potential impact of an expanded genetic code on protein function. Proc.Natl.Acad.Sci.USA, 112, 2015
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4ZJ2
 
 | Crystal Structure of p-acrylamido-phenylalanine modified TEM1 beta-lactamase from Escherichia coli :E166N mutant | Descriptor: | Beta-lactamase TEM | Authors: | Xiao, H, Nasertorabi, F, Choi, S, Han, G.W, Reed, S.A, Stevens, C.S, Schultz, P.G. | Deposit date: | 2015-04-28 | Release date: | 2015-05-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Exploring the potential impact of an expanded genetic code on protein function. Proc.Natl.Acad.Sci.USA, 112, 2015
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4ZJ3
 
 | Crystal structure of cephalexin bound acyl-enzyme intermediate of Val216AcrF mutant TEM1 beta-lactamase from Escherichia coli: E166N and V216AcrF mutant. | Descriptor: | Beta-lactamase TEM | Authors: | Xiao, H, Nasertorabi, F, Choi, S, Han, G.W, Reed, S.A, Stevens, R.C, Schultz, P.G. | Deposit date: | 2015-04-29 | Release date: | 2015-05-20 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Exploring the potential impact of an expanded genetic code on protein function. Proc.Natl.Acad.Sci.USA, 112, 2015
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3EGZ
 
 | Crystal structure of an in vitro evolved tetracycline aptamer and artificial riboswitch | Descriptor: | 7-CHLOROTETRACYCLINE, MAGNESIUM ION, Tetracycline aptamer and artificial riboswitch, ... | Authors: | Xiao, H, Edwards, T.E, Ferre-D'Amare, A.R. | Deposit date: | 2008-09-11 | Release date: | 2008-10-28 | Last modified: | 2024-10-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural basis for specific, high-affinity tetracycline binding by an in vitro evolved aptamer and artificial riboswitch Chem.Biol., 15, 2008
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3CUL
 
 | Aminoacyl-tRNA synthetase ribozyme | Descriptor: | MAGNESIUM ION, POTASSIUM ION, RNA (92-MER), ... | Authors: | Xiao, H, Murakami, H, Suga, H, Ferre-D'Amare, A.R. | Deposit date: | 2008-04-16 | Release date: | 2008-06-24 | Last modified: | 2024-11-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of specific tRNA aminoacylation by a small in vitro selected ribozyme. Nature, 454, 2008
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8I1V
 
 | The asymmetric unit of P22 procapsid | Descriptor: | Major capsid protein, Scaffolding protein | Authors: | Xiao, H, Liu, H.R, Cheng, L.P. | Deposit date: | 2023-01-13 | Release date: | 2023-03-08 | Last modified: | 2025-06-18 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures. Viruses, 15, 2023
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8I1T
 
 | The asymmetric unit of P22 empty capsid | Descriptor: | Major capsid protein | Authors: | Xiao, H, Liu, H.R, Cheng, L.P. | Deposit date: | 2023-01-13 | Release date: | 2023-03-08 | Last modified: | 2025-07-02 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Assembly and Capsid Expansion Mechanism of Bacteriophage P22 Revealed by High-Resolution Cryo-EM Structures. Viruses, 15, 2023
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5Y2K
 
 | A human antibody AF4H1L1 | Descriptor: | a group 2 HA binding antibody AF4H1K1 Fab heavy chain, a group 2 HA binding antibody AF4H1K1 Fab light chain | Authors: | Xiao, H, Qi, J, Gao, F.G. | Deposit date: | 2017-07-26 | Release date: | 2019-01-30 | Last modified: | 2024-11-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | An H3-clade neutralizing antibody screened from an H7N9 patient that binds group 2 influenza A hemagglutinins To Be Published
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5Y2M
 
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5Y2L
 
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8K36
 
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8K35
 
 | Structure of the bacteriophage lambda tail tip complex | Descriptor: | IRON/SULFUR CLUSTER, Tail tip assembly protein I, Tail tip protein L, ... | Authors: | Xiao, H, Tan, L, Cheng, L.P, Liu, H.R. | Deposit date: | 2023-07-14 | Release date: | 2023-11-15 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly. Plos Biol., 21, 2023
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8K37
 
 | Structure of the bacteriophage lambda neck | Descriptor: | Head-tail connector protein FII, Tail tube protein, Tail tube terminator protein | Authors: | Xiao, H, Tan, L, Cheng, L.P, Liu, H.R. | Deposit date: | 2023-07-14 | Release date: | 2023-11-15 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly. Plos Biol., 21, 2023
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8K38
 
 | The structure of bacteriophage lambda portal-adaptor | Descriptor: | Head completion protein, Portal protein B | Authors: | Xiao, H, Tan, L, Cheng, L.P, Liu, H.R. | Deposit date: | 2023-07-14 | Release date: | 2023-11-15 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly. Plos Biol., 21, 2023
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8K39
 
 | Structure of the bacteriophage lambda portal vertex | Descriptor: | Major capsid protein, Portal protein B | Authors: | Xiao, H, Tan, L, Cheng, L.P, Liu, H.R. | Deposit date: | 2023-07-14 | Release date: | 2023-11-15 | Last modified: | 2024-01-17 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Structure of the siphophage neck-Tail complex suggests that conserved tail tip proteins facilitate receptor binding and tail assembly. Plos Biol., 21, 2023
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7E4K
 
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9JG6
 
 | The tail-complex structure of phage P22 | Descriptor: | Endorhamnosidase, P22 tail accessory factor, Phage stabilisation protein, ... | Authors: | Liu, H.R, Xiao, H. | Deposit date: | 2024-09-06 | Release date: | 2025-02-26 | Last modified: | 2025-04-30 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structure of the scaffolding protein and portal within the bacteriophage P22 procapsid provides insights into the self-assembly process. Plos Biol., 23, 2025
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9KYV
 
 | The scaffold dimer of phage P22 | Descriptor: | Scaffolding protein | Authors: | Liu, H.R, Xiao, H. | Deposit date: | 2024-12-09 | Release date: | 2025-02-26 | Last modified: | 2025-04-30 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Structure of the scaffolding protein and portal within the bacteriophage P22 procapsid provides insights into the self-assembly process. Plos Biol., 23, 2025
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9KYW
 
 | The scaffold C-loop of phage P22 | Descriptor: | Portal protein, Scaffolding protein | Authors: | Liu, H.R, Xiao, H. | Deposit date: | 2024-12-09 | Release date: | 2025-02-26 | Last modified: | 2025-04-30 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | Structure of the scaffolding protein and portal within the bacteriophage P22 procapsid provides insights into the self-assembly process. Plos Biol., 23, 2025
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9JGA
 
 | P22 procapsid portal | Descriptor: | Portal protein | Authors: | Liu, H.R, Xiao, H. | Deposit date: | 2024-09-06 | Release date: | 2025-02-26 | Last modified: | 2025-04-30 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structure of the scaffolding protein and portal within the bacteriophage P22 procapsid provides insights into the self-assembly process. Plos Biol., 23, 2025
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9KYY
 
 | The scaffold trimer of phage P22 | Descriptor: | Scaffolding protein | Authors: | Liu, H.R, Xiao, H. | Deposit date: | 2024-12-09 | Release date: | 2025-02-26 | Last modified: | 2025-04-30 | Method: | ELECTRON MICROSCOPY (6.9 Å) | Cite: | Structure of the scaffolding protein and portal within the bacteriophage P22 procapsid provides insights into the self-assembly process. Plos Biol., 23, 2025
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