3OJW | | DISULFIDE CROSSLINKED CYTOCHROME P450 REDUCTASE INACTIVE | | Descriptor: | NADPH-cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Xia, C., Hamdane, D., Shen, A., Choi, V., Kasper, C., Zhang, H., Im, S.-C., Waskell, L., Kim, J.-J.P. | | Deposit date: | 2010-08-23 | | Release date: | 2011-02-23 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding.
J.Biol.Chem., 286, 2011
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3OJX | | DISULFIDE CROSSLINKED CYTOCHROME P450 REDUCTASE INACTIVE | | Descriptor: | NADPH-Cytochrome P450 Reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Hamdane, D., Shen, A., Choi, V., Kasper, C., Zhang, H., Im, S.-C., Waskell, L., Kim, J.-J.P. | | Deposit date: | 2010-08-23 | | Release date: | 2011-02-23 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding.
J.Biol.Chem., 286, 2011
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3QE2 | | CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 REDUCTASE | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN-ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Xia, C., Marohnic, C., Panda, S.P., Masters, B.S., Kim, J.-J.P. | | Deposit date: | 2011-01-19 | | Release date: | 2011-08-03 | | Last modified: | 2011-08-31 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3QFC | | CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 (V492E MUTANT) | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN-ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Xia, C., Marohnic, C., Panda, S.P., Masters, B.S., Kim, J.-J.P. | | Deposit date: | 2011-01-21 | | Release date: | 2011-08-03 | | Last modified: | 2011-08-31 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3QFR | | CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 REDUCTASE (R457H MUTANT) | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN-ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, ... | | Authors: | Xia, C., Marohnic, C., Panda, S.P., Masters, B.S., Kim, J.-J.P. | | Deposit date: | 2011-01-22 | | Release date: | 2011-08-03 | | Last modified: | 2011-08-31 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3QFS | | CRYSTAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE (FAD/NADPH DOMAIN) | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Xia, C., Marohnic, C., Panda, S.P., Masters, B.S., Kim, J.-J.P. | | Deposit date: | 2011-01-22 | | Release date: | 2011-08-17 | | Last modified: | 2011-08-31 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3QFT | | CRYSTAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE (FAD/NADPH DOMAIN AND R457H MUTANT) | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Xia, C., Marohnic, C., Panda, S.P., Masters, B.S., Kim, J.-J.P. | | Deposit date: | 2011-01-22 | | Release date: | 2011-08-17 | | Last modified: | 2011-08-31 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3HR4 | | HUMAN INOS REDUCTASE AND CALMODULIN COMPLEX | | Descriptor: | Nitric oxide synthase, inducible, Calmodulin, ... | | Authors: | Xia, C., Misra, I., Iyanaki, T., Kim, J.J.K. | | Deposit date: | 2009-06-08 | | Release date: | 2009-09-08 | | Last modified: | 2018-03-07 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Regulation of Interdomain Interactions by CaM in Inducible Nitric Oxide Synthase
J.Biol.Chem., 2009
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5URD | | WILD TYPE RAT CYPOR BOUND WITH NADP+ - OXIDIZED FORM | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J. | | Deposit date: | 2017-02-10 | | Release date: | 2018-02-14 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
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5URE | | WILD TYPE RAT CYPOR BOUND WITH NADP+ - REDUCED FORM | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J. | | Deposit date: | 2017-02-10 | | Release date: | 2018-02-14 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
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5URG | | RAT CYPOR D632F MUTANT | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J. | | Deposit date: | 2017-02-10 | | Release date: | 2018-02-14 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
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5URH | | CYPOR/D632A WITH NADP+ | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J. | | Deposit date: | 2017-02-10 | | Release date: | 2018-02-14 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
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5URI | | RAT CYPOR/D632A WITH 2'-AMP | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J. | | Deposit date: | 2017-02-10 | | Release date: | 2018-02-14 | | Last modified: | 2020-01-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
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6NJR | | SPIN-LABELED T177C/A637C MUTANT OF RAT CYPOR | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J.K. | | Deposit date: | 2019-01-04 | | Release date: | 2019-02-27 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural and Functional Studies of the Membrane-Binding Domain of NADPH-Cytochrome P450 Oxidoreductase.
Biochemistry, 58, 2019
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5EMN | | CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 REDUCTASE(A287P MUTANT) | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Marohnic, C., Panda, S., Masters, B.S., Kim, J.J.K. | | Deposit date: | 2015-11-06 | | Release date: | 2016-08-17 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype.
J.Biol.Chem., 291, 2016
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5FA6 | | WILD TYPE HUMAN CYPOR | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Marohnic, C., Panda, S., Masters, B.S., Kim, J.J.K. | | Deposit date: | 2015-12-11 | | Release date: | 2016-08-17 | | Last modified: | 2016-10-05 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype.
J.Biol.Chem., 291, 2016
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4Y7C | | RAT CYPOR MUTANT - G141DEL/E142N | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J.P. | | Deposit date: | 2015-02-13 | | Release date: | 2016-02-24 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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4Y9R | | RAT CYPOR MUTANT - G141DEL | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-02 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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4Y9U | | RAT CYPOR MUTANT - G143DEL | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-02 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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4YAF | | RAT CYPOR WITH 2'-AMP | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-09 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.91 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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4YAL | | REDUCED CYPOR WITH 2'-AMP | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-02 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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4YAO | | REDUCED CYPOR MUTANT - G143DEL | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-02 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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4YAU | | REDUCED CYPOR MUTANT - G141DEL/E142N | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-02 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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4YAW | | REDUCED CYPOR MUTANT - G141DEL | | Descriptor: | NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xia, C., Kim, J.J.P. | | Deposit date: | 2015-02-17 | | Release date: | 2016-03-02 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
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5HBA | |
