Author results

3OJW
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DISULFIDE CROSSLINKED CYTOCHROME P450 REDUCTASE INACTIVE
Descriptor:NADPH-cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Xia, C., Hamdane, D., Shen, A., Choi, V., Kasper, C., Zhang, H., Im, S.-C., Waskell, L., Kim, J.-J.P.
Deposit date:2010-08-23
Release date:2011-02-23
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding.
J.Biol.Chem., 286, 2011
3OJX
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DISULFIDE CROSSLINKED CYTOCHROME P450 REDUCTASE INACTIVE
Descriptor:NADPH-Cytochrome P450 Reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Hamdane, D., Shen, A., Choi, V., Kasper, C., Zhang, H., Im, S.-C., Waskell, L., Kim, J.-J.P.
Deposit date:2010-08-23
Release date:2011-02-23
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Conformational Changes of NADPH-Cytochrome P450 Oxidoreductase Are Essential for Catalysis and Cofactor Binding.
J.Biol.Chem., 286, 2011
3QE2
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CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 REDUCTASE
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN-ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, ...
Authors:Xia, C., Marohnic, C., Panda, S.P., Masters, B.S., Kim, J.-J.P.
Deposit date:2011-01-19
Release date:2011-08-03
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency.
Proc.Natl.Acad.Sci.USA, 108, 2011
3QFC
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CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 (V492E MUTANT)
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN-ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, ...
Authors:Xia, C., Marohnic, C., Panda, S.P., Masters, B.S., Kim, J.-J.P.
Deposit date:2011-01-21
Release date:2011-08-03
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency.
Proc.Natl.Acad.Sci.USA, 108, 2011
3QFR
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CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 REDUCTASE (R457H MUTANT)
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN-ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, ...
Authors:Xia, C., Marohnic, C., Panda, S.P., Masters, B.S., Kim, J.-J.P.
Deposit date:2011-01-22
Release date:2011-08-03
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency.
Proc.Natl.Acad.Sci.USA, 108, 2011
3QFS
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CRYSTAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE (FAD/NADPH DOMAIN)
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Xia, C., Marohnic, C., Panda, S.P., Masters, B.S., Kim, J.-J.P.
Deposit date:2011-01-22
Release date:2011-08-17
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency.
Proc.Natl.Acad.Sci.USA, 108, 2011
3QFT
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CRYSTAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE (FAD/NADPH DOMAIN AND R457H MUTANT)
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Xia, C., Marohnic, C., Panda, S.P., Masters, B.S., Kim, J.-J.P.
Deposit date:2011-01-22
Release date:2011-08-17
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural basis for human NADPH-cytochrome P450 oxidoreductase deficiency.
Proc.Natl.Acad.Sci.USA, 108, 2011
3HR4
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HUMAN INOS REDUCTASE AND CALMODULIN COMPLEX
Descriptor:Nitric oxide synthase, inducible, Calmodulin, ...
Authors:Xia, C., Misra, I., Iyanaki, T., Kim, J.J.K.
Deposit date:2009-06-08
Release date:2009-09-08
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulation of Interdomain Interactions by CaM in Inducible Nitric Oxide Synthase
J.Biol.Chem., 2009
5URD
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WILD TYPE RAT CYPOR BOUND WITH NADP+ - OXIDIZED FORM
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.
Deposit date:2017-02-10
Release date:2018-02-14
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
5URE
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WILD TYPE RAT CYPOR BOUND WITH NADP+ - REDUCED FORM
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.
Deposit date:2017-02-10
Release date:2018-02-14
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
5URG
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RAT CYPOR D632F MUTANT
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.
Deposit date:2017-02-10
Release date:2018-02-14
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
5URH
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CYPOR/D632A WITH NADP+
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.
Deposit date:2017-02-10
Release date:2018-02-14
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
5URI
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RAT CYPOR/D632A WITH 2'-AMP
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.
Deposit date:2017-02-10
Release date:2018-02-14
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
Biochemistry, 57, 2018
6NJR
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SPIN-LABELED T177C/A637C MUTANT OF RAT CYPOR
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.K.
Deposit date:2019-01-04
Release date:2019-02-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Spin-Labeled T177C/A637C Mutant of Rat CYPOR
To Be Published
5EMN
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CRYSTAL STRUCTURE OF HUMAN NADPH-CYTOCHROME P450 REDUCTASE(A287P MUTANT)
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Marohnic, C., Panda, S., Masters, B.S., Kim, J.J.K.
Deposit date:2015-11-06
Release date:2016-08-17
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype.
J.Biol.Chem., 291, 2016
5FA6
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WILD TYPE HUMAN CYPOR
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Marohnic, C., Panda, S., Masters, B.S., Kim, J.J.K.
Deposit date:2015-12-11
Release date:2016-08-17
Last modified:2016-10-05
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Instability of the Human Cytochrome P450 Reductase A287P Variant Is the Major Contributor to Its Antley-Bixler Syndrome-like Phenotype.
J.Biol.Chem., 291, 2016
4Y7C
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RAT CYPOR MUTANT - G141DEL/E142N
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.P.
Deposit date:2015-02-13
Release date:2016-02-24
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
4Y9R
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RAT CYPOR MUTANT - G141DEL
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.P.
Deposit date:2015-02-17
Release date:2016-03-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
4Y9U
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RAT CYPOR MUTANT - G143DEL
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.P.
Deposit date:2015-02-17
Release date:2016-03-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
4YAF
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RAT CYPOR WITH 2'-AMP
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.P.
Deposit date:2015-02-17
Release date:2016-03-09
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
4YAL
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REDUCED CYPOR WITH 2'-AMP
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.P.
Deposit date:2015-02-17
Release date:2016-03-02
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
4YAO
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REDUCED CYPOR MUTANT - G143DEL
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.P.
Deposit date:2015-02-17
Release date:2016-03-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
4YAU
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REDUCED CYPOR MUTANT - G141DEL/E142N
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.P.
Deposit date:2015-02-17
Release date:2016-03-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
4YAW
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REDUCED CYPOR MUTANT - G141DEL
Descriptor:NADPH--cytochrome P450 reductase, FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Xia, C., Kim, J.J.P.
Deposit date:2015-02-17
Release date:2016-03-02
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
J.Biol.Chem., 291, 2016
5HBA
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GLOBULAR DOMAIN OF ZEBRAFISH COMPLEMENT 1QA PROTEIN
Descriptor:Uncharacterized protein, SULFATE ION
Authors:Xia, C., Yuan, H., Chen, R.
Deposit date:2015-12-31
Release date:2016-07-27
Last modified:2017-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of zebrafish complement 1qA globular domain.
Protein Sci., 25, 2016
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