Author results

6QH5
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AP2 CLATHRIN ADAPTOR MU2T156-PHOSPHORYLATED CORE IN CLOSED CONFORMATION
Descriptor:AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Wrobel, A.G., Owen, D.J., McCoy, A.J., Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Last modified:2020-10-07
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6QH6
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AP2 CLATHRIN ADAPTOR CORE WITH TWO CARGO PEPTIDES IN OPEN+ CONFORMATION
Descriptor:AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Wrobel, A.G., Owen, D.J., McCoy, A.J., Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (5 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6QH7
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AP2 CLATHRIN ADAPTOR MU2T156-PHOSPHORYLATED CORE WITH TWO CARGO PEPTIDES IN OPEN+ CONFORMATION
Descriptor:AP-2 complex subunit alpha, AP-2 complex subunit beta, ADAPTOR-RELATED PROTEIN COMPLEX 2, ...
Authors:Wrobel, A.G., Owen, D.J., McCoy, A.J., Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6ZGE
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UNCLEAVABLE SPIKE PROTEIN OF SARS-COV-2 IN CLOSED CONFORMATION
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-06-18
Release date:2020-07-01
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects.
Nat.Struct.Mol.Biol., 27, 2020
6ZGF
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SPIKE PROTEIN OF RATG13 BAT CORONAVIRUS IN CLOSED CONFORMATION
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-06-18
Release date:2020-07-01
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects.
Nat.Struct.Mol.Biol., 27, 2020
6ZGG
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FURIN CLEAVED SPIKE PROTEIN OF SARS-COV-2 WITH ONE RBD ERECT
Descriptor:Spike glycoprotein
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-06-18
Release date:2020-07-01
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects.
Nat.Struct.Mol.Biol., 27, 2020
6ZGH
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FURIN CLEAVED SPIKE PROTEIN OF SARS-COV-2 IN INTERMEDIATE CONFORMATION
Descriptor:Receptor-type tyrosine-protein phosphatase S,Spike glycoprotein,Fibritin
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-06-18
Release date:2020-07-01
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects.
Nat.Struct.Mol.Biol., 27, 2020
6ZGI
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FURIN CLEAVED SPIKE PROTEIN OF SARS-COV-2 IN CLOSED CONFORMATION
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-06-18
Release date:2020-07-01
Last modified:2020-09-16
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:SARS-CoV-2 and bat RaTG13 spike glycoprotein structures inform on virus evolution and furin-cleavage effects.
Nat.Struct.Mol.Biol., 27, 2020
7A5R
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COMPLEX OF SARS-COV-2 SPIKE AND CR3022 FAB (NON-UNIFORM REFINEMENT)
Descriptor:CR3022 Fab Heavy Chain, CR3022 Fab Light Chain, Spike glycoprotein, ...
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-08-21
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein
To be published
7A5S
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COMPLEX OF SARS-COV-2 SPIKE AND CR3022 FAB (HOMOGENEOUS REFINEMENT)
Descriptor:CR3022 Fab Heavy Chain, CR3022 Fab Light Chain, Spike glycoprotein, ...
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-08-21
Release date:2020-09-16
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Antibody-mediated disruption of the SARS-CoV-2 spike glycoprotein
To be published
7A91
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DISSOCIATED S1 DOMAIN OF SARS-COV-2 SPIKE BOUND TO ACE2 (NON-UNIFORM REFINEMENT)
Descriptor:Angiotensin-converting enzyme 2, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion.
Nature, 2020
7A92
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DISSOCIATED S1 DOMAIN OF SARS-COV-2 SPIKE BOUND TO ACE2 (UNMASKED REFINEMENT)
Descriptor:Angiotensin-converting enzyme 2, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-30
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion.
Nature, 2020
7A93
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SARS-COV-2 SPIKE GLYCOPROTEIN WITH 2 RBDS ERECT
Descriptor:Spike glycoprotein
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion.
Nature, 2020
7A94
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SARS-COV-2 SPIKE GLYCOPROTEIN WITH 1 ACE2 BOUND
Descriptor:Spike glycoprotein, Angiotensin-converting enzyme 2, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion.
Nature, 2020
7A95
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SARS-COV-2 SPIKE GLYCOPROTEIN WITH 1 ACE2 BOUND AND 1 RBD ERECT IN CLOCKWISE DIRECTION
Descriptor:Spike glycoprotein, Angiotensin-converting enzyme 2
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion.
Nature, 2020
7A96
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SARS-COV-2 SPIKE GLYCOPROTEIN WITH 1 ACE2 BOUND AND 1 RBD ERECT IN ANTICLOCKWISE DIRECTION
Descriptor:Spike glycoprotein, Angiotensin-converting enzyme 2
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion.
Nature, 2020
7A97
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SARS-COV-2 SPIKE GLYCOPROTEIN WITH 2 ACE2 BOUND
Descriptor:Spike glycoprotein, Angiotensin-converting enzyme 2
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-16
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion.
Nature, 2020
7A98
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SARS-COV-2 SPIKE GLYCOPROTEIN WITH 3 ACE2 BOUND
Descriptor:Spike glycoprotein, Angiotensin-converting enzyme 2
Authors:Benton, D.J., Wrobel, A.G., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-09-01
Release date:2020-09-23
Last modified:2020-09-30
Method:ELECTRON MICROSCOPY (5.4 Å)
Cite:Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion.
Nature, 2020
6RH5
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SOLUTION STRUCTURE AND 1H, 13C AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR NECAP1 PHEAR DOMAIN
Descriptor:Adaptin ear-binding coat-associated protein 1
Authors:Owen, D.J., Neuhaus, D., Yang, J.-C., Herrmann, T.
Deposit date:2019-04-18
Release date:2019-09-04
Method:SOLUTION NMR
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6RH6
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SOLUTION STRUCTURE AND 1H, 13C AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR THE COMPLEX OF NECAP1 PHEAR DOMAIN WITH PHOSPHORYLATED AP2 MU2 148-163
Descriptor:Adaptin ear-binding coat-associated protein 1, AP-2 complex subunit mu
Authors:Owen, D.J., Neuhaus, D., Yang, J.-C., Herrmann, T.
Deposit date:2019-04-18
Release date:2019-09-04
Method:SOLUTION NMR
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
5JP2
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FCHO1 MU HOMOLOGY DOMAIN (DANIO RERIO) WITH BOUND EPS15 PEPTIDE
Descriptor:Epidermal growth factor receptor substrate 15, F-BAR domain only protein 1, ZINC ION
Authors:McCoy, A.J., Wrobel, A., Owen, D.J.
Deposit date:2016-05-03
Release date:2016-06-08
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transient Fcho1/2Eps15/RAP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
Dev.Cell, 37, 2016
5M0W
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N-TERMINAL DOMAIN OF MOUSE SHISA 3
Descriptor:Protein shisa-3 homolog, SULFATE ION, GLYCEROL, ...
Authors:Lohkamp, B., Ojala, J.R.M.
Deposit date:2016-10-06
Release date:2017-04-05
Last modified:2020-03-11
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Ab initio solution of macromolecular crystal structures without direct methods.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2YEZ
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COMPLEX OF A B21 CHICKEN MHC CLASS I MOLECULE AND A 10MER CHICKEN PEPTIDE
Descriptor:MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B21, BETA-2-MICROGLOBULIN, 14-3-3 PROTEIN THETA
Authors:Chappell, P., Roversi, P., Harrison, M.C., Mears, L.E., Kaufman, J.F., Lea, S.M.
Deposit date:2011-03-31
Release date:2012-04-11
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015
4CVX
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COMPLEX OF A B2 CHICKEN MHC CLASS I MOLECULE AND A 9MER CHICKEN PEPTIDE
Descriptor:MHC CLASS I ALPHA CHAIN 2, BETA-2-MICROGLOBULIN, SELF-PEPTIDE
Authors:Chappell, P.E., Roversi, P., Harrison, M.C., Mears, L.E., Kaufman, J.F., Lea, S.M.
Deposit date:2014-03-31
Release date:2015-05-06
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015
4CVZ
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COMPLEX OF A B21 CHICKEN MHC CLASS I MOLECULE AND A 10MER CHICKEN PEPTIDE
Descriptor:MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B21, BETA-2-MICROGLOBULIN, PEPTIDE, ...
Authors:Chappell, P.E., Roversi, P., Harrison, M.C., Mears, L.E., Kaufman, J.F., Lea, S.M.
Deposit date:2014-03-31
Release date:2015-05-06
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015
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170383
PDB entries from 2020-10-28