Author results

6QH5
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AP2 CLATHRIN ADAPTOR MU2T156-PHOSPHORYLATED CORE IN CLOSED CONFORMATION
Descriptor:AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Wrobel, A.G., Owen, D.J., McCoy, A.J., Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6QH6
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AP2 CLATHRIN ADAPTOR CORE WITH TWO CARGO PEPTIDES IN OPEN+ CONFORMATION
Descriptor:AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
Authors:Wrobel, A.G., Owen, D.J., McCoy, A.J., Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (5 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6QH7
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AP2 CLATHRIN ADAPTOR MU2T156-PHOSPHORYLATED CORE WITH TWO CARGO PEPTIDES IN OPEN+ CONFORMATION
Descriptor:AP-2 complex subunit alpha, AP-2 complex subunit beta, ADAPTOR-RELATED PROTEIN COMPLEX 2, ...
Authors:Wrobel, A.G., Owen, D.J., McCoy, A.J., Evans, P.R.
Deposit date:2019-01-15
Release date:2019-09-04
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6ZGE
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UNCLEAVABLE SPIKE PROTEIN OF SARS-COV-2 IN CLOSED CONFORMATION
Descriptor:Spike glycoprotein, N-ACETYL-D-GLUCOSAMINE
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-06-18
Release date:2020-07-01
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Evolution of SARS-CoV-2 spike glycoprotein
To be published
6ZGF
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SPIKE PROTEIN OF RATG13 BAT CORONAVIRUS IN CLOSED CONFORMATION
Descriptor:Spike glycoprotein, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-06-18
Release date:2020-07-01
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Evolution of SARS-CoV-2 spike glycoprotein
To be published
6ZGG
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FURIN CLEAVED SPIKE PROTEIN OF SARS-COV-2 WITH ONE RBD ERECT
Descriptor:Spike glycoprotein
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-06-18
Release date:2020-07-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Evolution of SARS-CoV-2 spike glycoprotein
To be published
6ZGH
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FURIN CLEAVED SPIKE PROTEIN OF SARS-COV-2 IN INTERMEDIATE CONFORMATION
Descriptor:Receptor-type tyrosine-protein phosphatase S,Spike glycoprotein,Fibritin
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-06-18
Release date:2020-07-01
Method:ELECTRON MICROSCOPY (6.8 Å)
Cite:Evolution of SARS-CoV-2 spike glycoprotein
To Be Published
6ZGI
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FURIN CLEAVED SPIKE PROTEIN OF SARS-COV-2 IN CLOSED CONFORMATION
Descriptor:Spike glycoprotein, N-ACETYL-D-GLUCOSAMINE
Authors:Wrobel, A.G., Benton, D.J., Rosenthal, P.B., Gamblin, S.J.
Deposit date:2020-06-18
Release date:2020-07-01
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Evolution of SARS-CoV-2 spike glycoprotein
To be published
6RH5
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SOLUTION STRUCTURE AND 1H, 13C AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR NECAP1 PHEAR DOMAIN
Descriptor:Adaptin ear-binding coat-associated protein 1
Authors:Owen, D.J., Neuhaus, D., Yang, J.-C., Herrmann, T.
Deposit date:2019-04-18
Release date:2019-09-04
Method:SOLUTION NMR
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
6RH6
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SOLUTION STRUCTURE AND 1H, 13C AND 15N CHEMICAL SHIFT ASSIGNMENTS FOR THE COMPLEX OF NECAP1 PHEAR DOMAIN WITH PHOSPHORYLATED AP2 MU2 148-163
Descriptor:Adaptin ear-binding coat-associated protein 1, AP-2 complex subunit mu
Authors:Owen, D.J., Neuhaus, D., Yang, J.-C., Herrmann, T.
Deposit date:2019-04-18
Release date:2019-09-04
Method:SOLUTION NMR
Cite:Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
5JP2
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FCHO1 MU HOMOLOGY DOMAIN (DANIO RERIO) WITH BOUND EPS15 PEPTIDE
Descriptor:Epidermal growth factor receptor substrate 15, F-BAR domain only protein 1, ZINC ION
Authors:McCoy, A.J., Wrobel, A., Owen, D.J.
Deposit date:2016-05-03
Release date:2016-06-08
Last modified:2016-06-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Transient Fcho1/2Eps15/RAP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.
Dev.Cell, 37, 2016
5M0W
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N-TERMINAL DOMAIN OF MOUSE SHISA 3
Descriptor:Protein shisa-3 homolog, SULFATE ION, GLYCEROL, ...
Authors:Lohkamp, B., Ojala, J.R.M.
Deposit date:2016-10-06
Release date:2017-04-05
Last modified:2020-03-11
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Ab initio solution of macromolecular crystal structures without direct methods.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2YEZ
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COMPLEX OF A B21 CHICKEN MHC CLASS I MOLECULE AND A 10MER CHICKEN PEPTIDE
Descriptor:MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B21, BETA-2-MICROGLOBULIN, 14-3-3 PROTEIN THETA
Authors:Chappell, P., Roversi, P., Harrison, M.C., Mears, L.E., Kaufman, J.F., Lea, S.M.
Deposit date:2011-03-31
Release date:2012-04-11
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015
4CVX
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COMPLEX OF A B2 CHICKEN MHC CLASS I MOLECULE AND A 9MER CHICKEN PEPTIDE
Descriptor:MHC CLASS I ALPHA CHAIN 2, BETA-2-MICROGLOBULIN, SELF-PEPTIDE
Authors:Chappell, P.E., Roversi, P., Harrison, M.C., Mears, L.E., Kaufman, J.F., Lea, S.M.
Deposit date:2014-03-31
Release date:2015-05-06
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015
4CVZ
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COMPLEX OF A B21 CHICKEN MHC CLASS I MOLECULE AND A 10MER CHICKEN PEPTIDE
Descriptor:MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B21, BETA-2-MICROGLOBULIN, PEPTIDE, ...
Authors:Chappell, P.E., Roversi, P., Harrison, M.C., Mears, L.E., Kaufman, J.F., Lea, S.M.
Deposit date:2014-03-31
Release date:2015-05-06
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015
4CW1
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COMPLEX OF A B14 CHICKEN MHC CLASS I MOLECULE AND A 9MER CHICKEN PEPTIDE
Descriptor:MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B14, BETA-2-MICROGLOBULIN, PEPTIDE
Authors:Chappell, P.E., Roversi, P., Harrison, M.C., Mears, L.E., Kaufman, J.F., Lea, S.M.
Deposit date:2014-03-31
Release date:2015-05-06
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015
4D0B
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COMPLEX OF A B21 CHICKEN MHC CLASS I MOLECULE AND A 10MER CHICKEN PEPTIDE
Descriptor:MHC CLASS I ANTIGEN, BETA-2-MICROGLOBULIN, PEPTIDE
Authors:Chappell, P.E., Roversi, P., Harrison, M.C., Mears, L.E., Kaufman, J.F., Lea, S.M.
Deposit date:2014-04-25
Release date:2015-05-06
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015
4D0C
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COMPLEX OF A B21 CHICKEN MHC CLASS I MOLECULE AND A 10MER CHICKEN PEPTIDE
Descriptor:MHC CLASS I ALPHA CHAIN 2, BETA-2-MICROGLOBULIN, 10MER PEPTIDE, ...
Authors:Chappell, P.E., Roversi, P., Harrison, M.C., Mears, L.E., Kaufman, J.F., Lea, S.M.
Deposit date:2014-04-25
Release date:2015-05-06
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015
4D0D
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COMPLEX OF A B2 CHICKEN MHC CLASS I MOLECULE AND A 8MER CHICKEN PEPTIDE
Descriptor:MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I GLYCOPROTEIN HAPLOTYPE B2, BETA-2-MICROGLOBULIN, SLP-76 ADAPTOR PROTEIN
Authors:Chappell, P.E., Roversi, P., Harrison, M.C., Mears, L.E., Kaufman, J.F., Lea, S.M.
Deposit date:2014-04-25
Release date:2015-05-06
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding.
Elife, 4, 2015
5FPI
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MU2 ADAPTIN SUBUNIT OF THE AP2 ADAPTOR (C-TERMINAL DOMAIN) COMPLEXED WITH INTEGRIN ALPHA4 INTERNALISATION PEPTIDE QYKSILQE
Descriptor:AP-2 COMPLEX SUBUNIT MU, INTEGRIN ALPHA-4 SUBUNIT
Authors:Owen, D.J., Evans, P.R., Ivaska, J.
Deposit date:2015-11-30
Release date:2016-01-20
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Selective Integrin Endocytosis is Driven by Alpha Chain:Ap2 Interactions
Nat.Struct.Mol.Biol., 23, 2016