5LO2
| Engineering protein stability with atomic precision in a monomeric miniprotein | Descriptor: | PPaTyr | Authors: | Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | Deposit date: | 2016-08-08 | Release date: | 2017-05-17 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Engineering protein stability with atomic precision in a monomeric miniprotein. Nat. Chem. Biol., 13, 2017
|
|
5LO3
| Engineering protein stability with atomic precision in a monomeric miniprotein | Descriptor: | PPaOMe | Authors: | Baker, E.G, Hudson, K.L, Williams, C, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | Deposit date: | 2016-08-08 | Release date: | 2017-05-17 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Engineering protein stability with atomic precision in a monomeric miniprotein. Nat. Chem. Biol., 13, 2017
|
|
1EYM
| FK506 BINDING PROTEIN MUTANT, HOMODIMERIC COMPLEX | Descriptor: | FK506 BINDING PROTEIN | Authors: | Rollins, C.T, Rivera, V.M, Woolfson, D.N, Keenan, T, Hatada, M, Adams, S.E, Andrade, L.J, Yaeger, D, van Schravendijk, M.R, Holt, D.A, Gilman, M, Clackson, T. | Deposit date: | 2000-05-07 | Release date: | 2000-08-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A ligand-reversible dimerization system for controlling protein-protein interactions. Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
6EIK
| A de novo designed heptameric coiled coil CC-Hept-I24E | Descriptor: | CC-Hept-I24E, FORMIC ACID, GLYCEROL | Authors: | Rhys, G.G, Burton, A.J, Dawson, W.M, Thomas, F, Woolfson, D.N. | Deposit date: | 2017-09-19 | Release date: | 2018-07-18 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | De Novo-Designed alpha-Helical Barrels as Receptors for Small Molecules. ACS Synth Biol, 7, 2018
|
|
6EIZ
| A de novo designed hexameric coiled coil CC-Hex2 with farnesol bound in the channel. | Descriptor: | (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol, CC-Hex2 | Authors: | Rhys, G.G, Burton, A.J, Dawson, W.M, Thomas, F, Woolfson, D.N. | Deposit date: | 2017-09-19 | Release date: | 2018-07-11 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | De Novo-Designed alpha-Helical Barrels as Receptors for Small Molecules. ACS Synth Biol, 7, 2018
|
|
5LO4
| Engineering protein stability with atomic precision in a monomeric miniprotein | Descriptor: | PPa-CH3 | Authors: | Baker, E.G, Williams, C, Hudson, K.L, Bartlett, G.G, Heal, J.W, Sessions, R.B, Crump, M.P, Woolfson, D.N. | Deposit date: | 2016-08-08 | Release date: | 2017-05-17 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Engineering protein stability with atomic precision in a monomeric miniprotein. Nat. Chem. Biol., 13, 2017
|
|
1SIF
| Crystal structure of a multiple hydrophobic core mutant of ubiquitin | Descriptor: | ubiquitin | Authors: | Benitez-Cardoza, C.G, Stott, K, Hirshberg, M, Went, H.M, Woolfson, D.N, Jackson, S.E. | Deposit date: | 2004-02-29 | Release date: | 2004-07-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Exploring sequence/folding space: folding studies on multiple hydrophobic core mutants of ubiquitin Biochemistry, 43, 2004
|
|
8QAB
| X-ray crystal structure of a de novo designed antiparallel coiled-coil hexameric alpha-helical barrel with 4 heptad repeats, apCCHex | Descriptor: | 1-methoxy-2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethane, apCCHex | Authors: | Naudin, E.N, Albanese, K.I, Petrenas, R, Woolfson, D.N. | Deposit date: | 2023-08-22 | Release date: | 2024-07-03 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Rationally seeded computational protein design of ɑ-helical barrels. Nat.Chem.Biol., 20, 2024
|
|
8QAC
| X-ray crystal structure of a de novo designed antiparallel coiled-coil 8-helix bundle with 4 heptad repeats, antiparallel 8-helix bundle-GLIA | Descriptor: | antiparallel 8-helix bundle-GLIA | Authors: | Albanese, K.I, Dawson, W.M, Petrenas, R, Woolfson, D.N. | Deposit date: | 2023-08-22 | Release date: | 2024-07-03 | Last modified: | 2024-08-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Rationally seeded computational protein design of ɑ-helical barrels. Nat.Chem.Biol., 20, 2024
|
|
8QAD
| |
8QKD
| |
8QAI
| |
8QAF
| |
2G0K
| |
2G0L
| Solution Structure of Neocarzinostatin Apo-Protein with bound Flavone | Descriptor: | 2-PHENYL-4H-CHROMEN-4-ONE, NEOCARZINOSTATIN | Authors: | Muskett, F.W, Stoneman, R.G, Caddick, S, Woolfson, D.N. | Deposit date: | 2006-02-13 | Release date: | 2006-03-28 | Last modified: | 2022-03-09 | Method: | SOLUTION NMR | Cite: | Synthetic Ligands for Apo-Neocarzinostatin J.Am.Chem.Soc., 128, 2006
|
|
1J5H
| Solution Structure of Apo-Neocarzinostatin | Descriptor: | Apo-Neocarzinostatin | Authors: | Urbaniak, M.D, Muskett, F.W, Finucane, M.D, Caddick, S, Woolfson, D.N. | Deposit date: | 2002-05-02 | Release date: | 2002-09-11 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution Structure of a Novel Chromoprotein Derived from Apo-Neocarzinostatin and a Synthetic Chromophore Biochemistry, 41, 2002
|
|
1J5I
| Solution Structure of a Novel Chromoprotein Derived from Apo-Neocarzinostatin and a Synthetic Chromophore | Descriptor: | 2-HYDROXY-7-METHOXY-5-METHYL-NAPHTHALENE-1-CARBOXYLIC ACID MESO-2,5-DIHYDROXY-CYCLOPENT-3-ENYL ESTER, PROTEIN (Apo-Neocarzinostatin) | Authors: | Urbaniak, M.D, Muskett, F.W, Finucane, M.D, Caddick, S, Woolfson, D.N. | Deposit date: | 2002-05-02 | Release date: | 2002-09-11 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution Structure of a Novel Chromoprotein Derived from Apo-Neocarzinostatin and a Synthetic Chromophore Biochemistry, 41, 2002
|
|
6XY1
| |
6XY0
| |
6XXZ
| |
4PN8
| A de novo designed pentameric coiled coil CC-Pent. | Descriptor: | CC-Pent | Authors: | Wood, C.W, Burton, A.J, Thomson, A.R, Brady, R.L, Woolfson, D.N. | Deposit date: | 2014-05-23 | Release date: | 2014-10-22 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Computational design of water-soluble alpha-helical barrels. Science, 346, 2014
|
|
4PND
| A de novo designed pentameric coiled coil CC-Pent_Variant | Descriptor: | CC-Pent_Variant | Authors: | Wood, C.W, Burton, A.J, Thomson, A.R, Brady, R.L, Woolfson, D.N. | Deposit date: | 2014-05-23 | Release date: | 2014-10-22 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Computational design of water-soluble alpha-helical barrels. Science, 346, 2014
|
|
4PN9
| A de novo designed hexameric coiled coil CC-Hex2 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CC-Hex2 | Authors: | Wood, C.W, Burton, A.J, Thomson, A.R, Brady, R.L, Woolfson, D.N. | Deposit date: | 2014-05-23 | Release date: | 2014-10-22 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Computational design of water-soluble alpha-helical barrels. Science, 346, 2014
|
|
4PNA
| A de novo designed heptameric coiled coil CC-Hept | Descriptor: | CC-Hept, GLYCEROL | Authors: | Burton, A.J, Wood, C.W, Thomson, A.R, Brady, R.L, Woolfson, D.N. | Deposit date: | 2014-05-23 | Release date: | 2014-10-22 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Computational design of water-soluble alpha-helical barrels. Science, 346, 2014
|
|
4PNB
| A de novo designed hexameric coiled coil CC-Hex3. | Descriptor: | CC-Hex3 | Authors: | Wood, C.W, Burton, A.J, Thomson, A.R, Brady, R.L, Woolfson, D.N. | Deposit date: | 2014-05-23 | Release date: | 2014-10-22 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.052 Å) | Cite: | Computational design of water-soluble alpha-helical barrels. Science, 346, 2014
|
|