6EIZ

A de novo designed hexameric coiled coil CC-Hex2 with farnesol bound in the channel.

Summary for 6EIZ

• Entry DOI: 10.2210/pdb6eiz/pdb
• Related: 6EIK
• Descriptor: CC-Hex2, (2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ol (3 entities in total)
• Functional Keywords: alpha-helical coiled-coil barrel, de novo protein
• Biological source: synthetic construct
• Total number of polymer chains: 6
• Total formula weight: 20028.20

Authors

Rhys, G.G.,Burton, A.J.,Dawson, W.M.,Thomas, F.,Woolfson, D.N. (deposition date: 2017-09-19, release date: 2018-07-11, Last modification date: 2024-01-17)

• Primary citation: Thomas, F.,Dawson, W.M.,Lang, E.J.M.,Burton, A.J.,Bartlett, G.J.,Rhys, G.G.,Mulholland, A.J.,Woolfson, D.N.; De Novo-Designed alpha-Helical Barrels as Receptors for Small Molecules.; ACS Synth Biol, 7:1808-1816, 2018; PubMed: 29944338; DOI: 10.1021/acssynbio.8b00225

Experimental method

X-RAY DIFFRACTION (1.85 Å)