6SXO
| Cryo-EM structure of the human Ebp1-ribosome complex | Descriptor: | 28S ribosomal RNA including ES27L-B (2839-3265), 5.8S ribosomal RNA, 60S ribosomal protein L19, ... | Authors: | Wild, K, Aleksic, M, Pfeffer, M, Sinning, I. | Deposit date: | 2019-09-26 | Release date: | 2020-02-19 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | MetAP-like Ebp1 occupies the human ribosomal tunnel exit and recruits flexible rRNA expansion segments. Nat Commun, 11, 2020
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5L3Q
| Structure of the GTPase heterodimer of human SRP54 and SRalpha | Descriptor: | ADENOSINE MONOPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | Authors: | Wild, K, Segnitz, B, Sinning, I. | Deposit date: | 2016-05-24 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex. J.Mol.Biol., 428, 2016
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3KTV
| Crystal structure of the human SRP19/S-domain SRP RNA complex | Descriptor: | MAGNESIUM ION, POTASSIUM ION, SRP RNA, ... | Authors: | Wild, K, Bange, G, Bozkurt, G, Sinning, I. | Deposit date: | 2009-11-26 | Release date: | 2010-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural insights into the assembly of the human and archaeal signal recognition particles. Acta Crystallogr.,Sect.D, 66, 2010
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3KTW
| Crystal structure of the SRP19/S-domain SRP RNA complex of Sulfolobus solfataricus | Descriptor: | MAGNESIUM ION, POTASSIUM ION, SRP RNA, ... | Authors: | Wild, K, Bange, G, Bozkurt, G, Sinning, I. | Deposit date: | 2009-11-26 | Release date: | 2010-02-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural insights into the assembly of the human and archaeal signal recognition particles. Acta Crystallogr.,Sect.D, 66, 2010
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2VTK
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1VTK
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3VTK
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1JID
| Human SRP19 in complex with helix 6 of Human SRP RNA | Descriptor: | HELIX 6 OF HUMAN SRP RNA, MAGNESIUM ION, SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN | Authors: | Wild, K, Sinning, I, Cusack, S. | Deposit date: | 2001-07-02 | Release date: | 2001-10-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of an early protein-RNA assembly complex of the signal recognition particle. Science, 294, 2001
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1ZAK
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1D4R
| 29-mer fragment of human srp rna helix 6 | Descriptor: | 29-MER OF MODIFIED SRP RNA HELIX 6, MAGNESIUM ION | Authors: | Wild, K, Weichenrieder, O, Leonard, G.A, Cusack, S. | Deposit date: | 1999-10-05 | Release date: | 1999-12-02 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 2 A structure of helix 6 of the human signal recognition particle RNA Structure Fold.Des., 7, 1999
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6ZQQ
| Structure of the Pmt3-MIR domain with bound ligands | Descriptor: | GLYCEROL, PMT3 isoform 1 | Authors: | Wild, K, Chiapparino, A, Hackmann, Y, Mortensen, S, Sinning, I. | Deposit date: | 2020-07-10 | Release date: | 2020-12-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Functional implications of MIR domains in protein O -mannosylation. Elife, 9, 2020
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6ZQP
| Structure of the Pmt2-MIR domain with bound ligands | Descriptor: | GLYCEROL, PMT2 isoform 1, SULFATE ION, ... | Authors: | Wild, K, Chiapparino, A, Hackmann, Y, Mortensen, S, Sinning, I. | Deposit date: | 2020-07-10 | Release date: | 2020-12-23 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Functional implications of MIR domains in protein O -mannosylation. Elife, 9, 2020
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5L3S
| Structure of the GTPase heterodimer of crenarchaeal SRP54 and FtsY | Descriptor: | GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | Authors: | Bange, G, Wild, K, Sinning, I. | Deposit date: | 2016-05-24 | Release date: | 2016-06-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex. J.Mol.Biol., 428, 2016
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5L3W
| Structure of the crenarchaeal FtsY GTPase bound to GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, Signal recognition particle receptor FtsY | Authors: | Bange, G, Wild, K, Sinning, I. | Deposit date: | 2016-05-24 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex. J.Mol.Biol., 428, 2016
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5L3R
| Structure of the GTPase heterodimer of chloroplast SRP54 and FtsY from Arabidopsis thaliana | Descriptor: | Cell division protein FtsY homolog, chloroplastic, GLYCEROL, ... | Authors: | Bange, G, Kribelbauer, J, Wild, K, Sinning, I. | Deposit date: | 2016-05-24 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex. J.Mol.Biol., 428, 2016
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5L3V
| Structure of the crenarchaeal SRP54 GTPase bound to GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, Signal recognition particle 54 kDa protein | Authors: | Bange, G, Wild, K, Sinning, I. | Deposit date: | 2016-05-24 | Release date: | 2016-06-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex. J.Mol.Biol., 428, 2016
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4JFN
| Crystal structure of the N-terminal, growth factor-like domain of the amyloid precursor protein bound to copper | Descriptor: | Amyloid beta A4 protein, COPPER (II) ION, GLYCEROL | Authors: | Wild, K, Baumkotter, F, Kins, S. | Deposit date: | 2013-02-28 | Release date: | 2014-07-23 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Amyloid precursor protein dimerization and synaptogenic function depend on copper binding to the growth factor-like domain J.Neurosci., 34, 2014
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3D8E
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1E8S
| Alu domain of the mammalian SRP (potential Alu retroposition intermediate) | Descriptor: | 7SL RNA, 88-MER, EUROPIUM (III) ION, ... | Authors: | Weichenrieder, O, Wild, K, Strub, K, Cusack, S. | Deposit date: | 2000-09-29 | Release date: | 2000-11-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure and Assembly of the Alu Domain of the Mammalian Signal Recognition Particle Nature, 408, 2000
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5AFF
| Symportin 1 chaperones 5S RNP assembly during ribosome biogenesis by occupying an essential rRNA binding site | Descriptor: | RIBOSOMAL PROTEIN L11, RIBOSOMAL PROTEIN L5, SYMPORTIN 1 | Authors: | Calvino, F.R, Kharde, S, Wild, K, Bange, G, Sinning, I. | Deposit date: | 2015-01-21 | Release date: | 2015-04-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.398 Å) | Cite: | Symportin 1 Chaperones 5S Rnp Assembly During Ribosome Biogenesis by Occupying an Essential Rrna-Binding Site. Nat.Commun., 6, 2015
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3DEO
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4WFM
| Structure of the complete bacterial SRP Alu domain | Descriptor: | Bacillus subtilis small cytoplasmic RNA (scRNA),RNA, COBALT HEXAMMINE(III), MAGNESIUM ION | Authors: | Kempf, G, Wild, K, Sinning, I. | Deposit date: | 2014-09-15 | Release date: | 2014-10-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the complete bacterial SRP Alu domain. Nucleic Acids Res., 42, 2014
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4P3F
| Structure of the human SRP68-RBD | Descriptor: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Signal recognition particle subunit SRP68 | Authors: | Grotwinkel, J.T, Wild, K, Sinning, I. | Deposit date: | 2014-03-07 | Release date: | 2014-04-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.699 Å) | Cite: | SRP RNA remodeling by SRP68 explains its role in protein translocation. Science, 344, 2014
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4P3E
| Structure of the human SRP S domain | Descriptor: | MAGNESIUM ION, SRP RNA (124-mer), Signal recognition particle 19 kDa protein, ... | Authors: | Grotwinkel, J.T, Wild, K, Sinning, I. | Deposit date: | 2014-03-07 | Release date: | 2014-04-16 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | SRP RNA remodeling by SRP68 explains its role in protein translocation. Science, 344, 2014
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4P3G
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