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1A0O
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CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY
Descriptor:CHEY, CHEA, MANGANESE (II) ION
Authors:Chinardet, N., Welch, M., Mourey, L., Birck, C., Samama, J.P.
Deposit date:1997-12-05
Release date:1998-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structure of the CheY-binding domain of histidine kinase CheA in complex with CheY.
Nat.Struct.Biol., 5, 1998
1FFG
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CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY AT 2.1 A RESOLUTION
Descriptor:CHEMOTAXIS PROTEIN CHEY, CHEMOTAXIS PROTEIN CHEA, MANGANESE (II) ION
Authors:Gouet, P., Chinardet, N., Welch, M., Guillet, V., Birck, C., Mourey, L., Samama, J.-P.
Deposit date:2000-07-25
Release date:2001-01-17
Last modified:2015-01-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Further insights into the mechanism of function of the response regulator CheY from crystallographic studies of the CheY--CheA(124--257) complex.
Acta Crystallogr.,Sect.D, 57, 2001
1FFS
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CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY FROM CRYSTALS SOAKED IN ACETYL PHOSPHATE
Descriptor:CHEMOTAXIS PROTEIN CHEY, CHEMOTAXIS PROTEIN CHEA, MANGANESE (II) ION
Authors:Gouet, P., Chinardet, N., Welch, M., Guillet, V., Birck, C., Mourey, L., Samama, J.-P.
Deposit date:2000-07-26
Release date:2001-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Further insights into the mechanism of function of the response regulator CheY from crystallographic studies of the CheY--CheA(124--257) complex.
Acta Crystallogr.,Sect.D, 57, 2001
1FFW
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CHEY-BINDING DOMAIN OF CHEA IN COMPLEX WITH CHEY WITH A BOUND IMIDO DIPHOSPHATE
Descriptor:CHEMOTAXIS PROTEIN CHEY, CHEMOTAXIS PROTEIN CHEA, MANGANESE (II) ION, ...
Authors:Gouet, P., Chinardet, N., Welch, M., Guillet, V., Birck, C., Mourey, L., Samama, J.-P.
Deposit date:2000-07-26
Release date:2001-01-17
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Further insights into the mechanism of function of the response regulator CheY from crystallographic studies of the CheY--CheA(124--257) complex.
Acta Crystallogr.,Sect.D, 57, 2001
5M2E
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APO STRUCTURE OF PSEUDOMONAS AERUGINOSA ISOCITRATE DEHYDROGENASE, ICD.
Descriptor:Isocitrate dehydrogenase [NADP]
Authors:Crousilles, A., Welch, M.
Deposit date:2016-10-12
Release date:2017-12-20
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Gluconeogenic precursor availability regulates flux through the glyoxylate shunt inPseudomonas aeruginosa.
J. Biol. Chem., 293, 2018
5OAS
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CRYSTAL STRUCTURE OF MALATE SYNTHASE G FROM PSEUDOMONAS AERUGINOSA IN APO FORM.
Descriptor:Malate synthase G, GLYCEROL, 1,2-ETHANEDIOL, ...
Authors:McVey, A.C., Welch, M.
Deposit date:2017-06-23
Release date:2017-10-18
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Structural and Functional Characterization of Malate Synthase G from Opportunistic Pathogen Pseudomonas aeruginosa.
Biochemistry, 56, 2017
6G1O
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STRUCTURE OF PSEUDOMONAS AERUGINOSA ISOCITRATE LYASE, ICL
Descriptor:Isocitrate lyase, CALCIUM ION, GLYOXYLIC ACID
Authors:Crousilles, A., Welch, M.
Deposit date:2018-03-21
Release date:2018-08-01
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (1.882 Å)
Cite:Gluconeogenic precursor availability regulates flux through the glyoxylate shunt inPseudomonas aeruginosa.
J. Biol. Chem., 293, 2018
6G3U
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STRUCTURE OF PSEUDOMONAS AERUGINOSA ISOCITRATE DEHYDROGENASE, IDH
Descriptor:Isocitrate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-OXOGLUTARIC ACID
Authors:Crousilles, A., Welch, M.
Deposit date:2018-03-26
Release date:2018-08-01
Last modified:2018-09-26
Method:X-RAY DIFFRACTION (2.707 Å)
Cite:Gluconeogenic precursor availability regulates flux through the glyoxylate shunt inPseudomonas aeruginosa.
J. Biol. Chem., 293, 2018
2GFS
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P38 KINASE CRYSTAL STRUCTURE IN COMPLEX WITH RO3201195
Descriptor:Mitogen-Activated Protein Kinase 14, [5-AMINO-1-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL](3-{[(2R)-2,3-DIHYDROXYPROPYL]OXY}PHENYL)METHANONE
Authors:Harris, S.F., Bertrand, J., Villasenor, A.
Deposit date:2006-03-23
Release date:2006-04-18
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.752 Å)
Cite:Discovery of S-[5-Amino-1-(4-fluorophenyl)-1H-pyrazol-4-yl]-[3-(2,3-dihydroxypropoxy)phenyl]-methanone (RO3201195), and Orally Bioavailable and Highly Selective Inhibitor of p38 Map Kinase
J.Med.Chem., 49, 2006
1OZ1
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P38 MITOGEN-ACTIVATED KINASE IN COMPLEX WITH 4-AZAINDOLE INHIBITOR
Descriptor:Mitogen-activated protein kinase 14, 3-(4-FLUOROPHENYL)-2-PYRIDIN-4-YL-1H-PYRROLO[3,2-B]PYRIDIN-1-OL
Authors:Lovejoy, B., Villasenor, A., Browner, M., Dunten, P.
Deposit date:2003-04-07
Release date:2003-09-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design and synthesis of 4-azaindoles as inhibitors of p38 MAP kinase.
J.Med.Chem., 46, 2003
3D4Q
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PYRAZOLE-BASED INHIBITORS OF B-RAF KINASE
Descriptor:B-Raf proto-oncogene serine/threonine-protein kinase, (1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime
Authors:Morales, T., Vigers, G.P.A., Brandhuber, B.J.
Deposit date:2008-05-14
Release date:2008-08-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Potent and selective pyrazole-based inhibitors of B-Raf kinase.
Bioorg.Med.Chem.Lett., 18, 2008
3PSB
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FURO[2,3-C]PYRIDINE-BASED INDANONE OXIMES AS POTENT AND SELECTIVE B-RAF INHIBITORS
Descriptor:B-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE, ethyl 3-{[1-(hydroxyamino)-2H-inden-5-yl]amino}thieno[2,3-c]pyridine-2-carboxylate
Authors:Morales, T., Vigers, G.P.A., Brandhuber, B.J.
Deposit date:2010-12-01
Release date:2011-01-19
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:The Discovery of furo[2,3-c]pyridine-based indanone oximes as potent and selective B-Raf inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
3PSD
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NON-OXIME PYRAZOLE BASED INHIBITORS OF B-RAF KINASE
Descriptor:B-RAF PROTO-ONCOGENE SERINE/THREONINE-PROTEIN KINASE, 6-[1-(piperidin-4-yl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl]indeno[1,2-c]pyrazole
Authors:Morales, T., Vigers, G.P.A., Brandhuber, B.J.
Deposit date:2010-12-01
Release date:2011-05-18
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Non-oxime pyrazole based inhibitors of B-Raf kinase.
Bioorg.Med.Chem.Lett., 21, 2011
1FFZ
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LARGE RIBOSOMAL SUBUNIT COMPLEXED WITH R(CC)-DA-PUROMYCIN
Descriptor:23S RIBOSOMAL RNA, R(P*CP*C*)-D(P*A)-R(P*(PU))
Authors:Nissen, P., Hansen, J., Ban, N., Moore, P.B., Steitz, T.A.
Deposit date:2000-07-26
Release date:2000-08-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The structural basis of ribosome activity in peptide bond synthesis.
Science, 289, 2000