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2Y7A
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CRYSTAL STRUCTURE OF UNLIGANDED GTB P156L
Descriptor:ABO GLYCOSYLTRANSFERASE, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE
Authors:Weadge, J., Palcic, M.M., Henriksen, A.
Deposit date:2011-01-31
Release date:2012-02-15
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structural and Biochemical Characterization of the Human Blood Group a and B Galactosyltransferases Possessing the Pro156Leu Mutation
To be Published
3S6B
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CRYSTAL STRUCTURE OF METHIONINE AMINOPEPTIDASE 1B FROM PLASMODIUM FALCIPARUM, PF10_0150
Descriptor:Methionine aminopeptidase, GLYCEROL, FE (III) ION
Authors:Wernimont, A.K., Artz, J.D., Crombet, L., Lew, J., Weadge, J., Tempel, W., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Hui, R., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2011-05-25
Release date:2011-06-29
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of methionine aminopeptidase 1b from Plasmodium Falciparum, PF10_0150
To be Published
3LLT
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CRYSTAL STRUCTURE OF PF14_0431, KINASE DOMAIN.
Descriptor:Serine/threonine kinase-1, PfLammer, SULFATE ION, ...
Authors:Wernimont, A.K., Tempel, W., Lin, Y.H., Loppnau, P., MacKenzie, F., Sullivan, H., Weadge, J., Kozieradzki, I., Cossar, D., Sinesterra, G., Vedadi, M., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Hui, R., Qiu, W., Hutchinson, A., Structural Genomics Consortium (SGC)
Deposit date:2010-01-29
Release date:2010-08-04
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of PF14_0431, kinase domain.
TO BE PUBLISHED
3MSE
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CRYSTAL STRUCTURE OF C-TERMINAL DOMAIN OF PF110239.
Descriptor:Calcium-dependent protein kinase, putative, CALCIUM ION, ...
Authors:Wernimont, A.K., Artz, J.D., Hutchinson, A., Sullivan, H., Weadge, J., Tempel, W., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Lin, Y.H., Neculai, A.M., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2010-04-29
Release date:2010-06-23
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of C-terminal domain of PF110239
To be Published
3O4Y
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CRYSTAL STRUCTURE OF CAD DOMAIN OF THE PLASMODIUM VIVAX CDPK, PVX_11610
Descriptor:Calcium-dependent protein kinase 3, CALCIUM ION, GLYCEROL, ...
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., Weadge, J., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2010-07-27
Release date:2010-08-25
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of CAD domain of the Plasmodium Vivax CDPK, PVX_11610
TO BE PUBLISHED
3P1W
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CRYSTAL STRUCTURE OF RAB GDI FROM PLASMODIUM FALCIPARUM, PFL2060C
Descriptor:RabGDI protein
Authors:Wernimont, A.K., Neculai, A.M., Weadge, J., MacKenzie, F., Cossar, D., Tempel, W., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Langsley, G., Bosch, J., Hui, R., Pizzaro, J.C., Hutchinson, A., Structural Genomics Consortium (SGC)
Deposit date:2010-09-30
Release date:2010-12-15
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of RAB GDI from Plasmodium Falciparum, PFL2060c
To be published
3PEH
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF AN HSP90 FROM PLASMODIUM FALCIPARUM, PFL1070C IN THE PRESENCE OF A THIENOPYRIMIDINE DERIVATIVE
Descriptor:Endoplasmin homolog, 2-amino-4-{2,4-dichloro-5-[2-(diethylamino)ethoxy]phenyl}-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide, SULFATE ION
Authors:Wernimont, A.K., Tempel, W., Hutchinson, A., Weadge, J., Cossar, D., MacKenzie, F., Vedadi, M., Senisterra, G., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Wyatt, P.G., Fairlamb, A.H., MacKenzie, C., Ferguson, M.A.J., Hui, R., Pizarro, J.C., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2010-10-26
Release date:2010-11-17
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of the N-terminal domain of an HSP90 from Plasmodium Falciparum, PFL1070c in the presence of a thienopyrimidine derivative
To be Published
3PEJ
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF AN HSP90 FROM PLASMODIUM FALCIPARUM, PFL1070C IN THE PRESENCE OF MACBECIN
Descriptor:Endoplasmin homolog, MACBECIN, SULFATE ION
Authors:Wernimont, A.K., Tempel, W., Hutchinson, A., Weadge, J., MacKenzie, F., Senisterra, G., Vedadi, M., Cossar, D., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Pizzaro, J.C., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2010-10-26
Release date:2010-11-17
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Crystal Structure of the N-terminal domain of an HSP90 from Plasmodium Falciparum, PFL1070c in the presence of Macbecin
To be Published
3TLX
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CRYSTAL STRUCTURE OF PF10_0086, ADENYLATE KINASE FROM PLASMODIUM FALCIPARUM
Descriptor:Adenylate kinase 2, MAGNESIUM ION, ADENOSINE MONOPHOSPHATE, ...
Authors:Wernimont, A.K., Loppnau, P., Crombet, L., Weadge, J., Perieteanu, A., Edwards, A.M., Arrowsmith, C.H., Park, H., Bountra, C., Hui, R., Amani, M., Structural Genomics Consortium (SGC)
Deposit date:2011-08-30
Release date:2011-10-26
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum
TO BE PUBLISHED
3PR3
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CRYSTAL STRUCTURE OF PLASMODIUM FALCIPARUM GLUCOSE-6-PHOSPHATE ISOMERASE (PF14_0341) IN COMPLEX WITH FRUCTOSE-6-PHOSPHATE
Descriptor:Glucose-6-phosphate isomerase, FRUCTOSE-6-PHOSPHATE, PHOSPHATE ION
Authors:Gileadi, T., Wernimont, A.K., Hutchinson, A., Weadge, J., Cossar, D., Lew, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Hills, T., Pizarro, J.C., Structural Genomics Consortium (SGC)
Deposit date:2010-11-29
Release date:2011-02-09
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of Plasmodium falciparum glucose-6-phosphate isomerase (PF14_0341) in complex with fructose-6-phosphate
To be Published
3QKI
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CRYSTAL STRUCTURE OF GLUCOSE-6-PHOSPHATE ISOMERASE (PF14_0341) FROM PLASMODIUM FALCIPARUM 3D7
Descriptor:Glucose-6-phosphate isomerase
Authors:Gileadi, T., Wernimont, A.K., Hutchinson, A., Weadge, J., Cossar, D., Lew, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Hui, R., Hills, T., Pizarro, J.C., Structural Genomics Consortium (SGC)
Deposit date:2011-02-01
Release date:2011-02-16
Last modified:2013-10-23
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of Glucose-6-Phosphate Isomerase (PF14_0341) from Plasmodium falciparum 3D7
TO BE PUBLISHED
3O6O
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF AN HSP90 FROM TRYPANOSOMA BRUCEI, TB10.26.1080 IN THE PRESENCE OF AN THE INHIBITOR BIIB021
Descriptor:Heat shock protein 83, 6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine, PENTAETHYLENE GLYCOL
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., Weadge, J., Li, Y., Kozieradzki, I., Cossar, D., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Wyatt, P., Fairlamb, A.H., Ferguson, M.A.J., Thompson, S., MacKenzie, C., Hui, R., Pizarro, J.C., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2010-07-29
Release date:2010-08-18
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design.
PLoS Negl Trop Dis, 7, 2013
3OMU
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF AN HSP90 FROM TRYPANOSOMA BRUCEI, TB10.26.1080 IN THE PRESENCE OF A THIENOPYRIMIDINE DERIVATIVE
Descriptor:Heat shock protein 83, 2-amino-4-{2,4-dichloro-5-[2-(diethylamino)ethoxy]phenyl}-N-ethylthieno[2,3-d]pyrimidine-6-carboxamide
Authors:Wernimont, A.K., Hutchinson, A., Sullivan, H., Weadge, J., Cossar, D., Li, Y., Kozieradzki, I., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Wyatt, P.G., Fairlamb, A.H., MacKenzie, C., Ferguson, M.A.J., Hui, R., Pizarro, J.C., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2010-08-27
Release date:2010-10-27
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design.
PLoS Negl Trop Dis, 7, 2013
3OPD
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF AN HSP90 FROM TRYPANOSOMA BRUCEI, TB10.26.1080 IN THE PRESENCE OF A BENZAMIDE DERIVATIVE
Descriptor:Heat shock protein 83, 4-[6,6-dimethyl-4-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-indazol-1-yl]-2-[(cis-4-hydroxycyclohexyl)amino]benzamide
Authors:Pizarro, J.C., Wernimont, A.K., Hutchinson, A., Sullivan, H., Chamberlain, K., Weadge, J., Cossar, D., Li, Y., Kozieradzki, I., Bochkarev, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Wyatt, P.G., Fairlamb, A.H., MacKenzie, C., Ferguson, M.A.J., Hui, R., Hills, T., Structural Genomics Consortium (SGC)
Deposit date:2010-08-31
Release date:2010-10-13
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Exploring the Trypanosoma brucei Hsp83 potential as a target for structure guided drug design.
PLoS Negl Trop Dis, 7, 2013