Author results

6I59
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LONG WAVELENGTH NATIVE-SAD PHASING OF SEN1 HELICASE
Descriptor:Helicase SEN1, ADENOSINE-5'-DIPHOSPHATE, 1,2-ETHANEDIOL, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges
To Be Published
6I5C
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LONG WAVELENGTH NATIVE-SAD PHASING OF TUBULIN-STATHMIN-TTL COMPLEX
Descriptor:Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ...
Authors:Basu, S., Olieric, V., Matsugaki, N., Kawano, Y., Takashi, T., Huang, C.Y., Leonarski, F., Yamada, Y., Vera, L., Olieric, N., Basquin, J., Wojdyla, J.A., Diederichs, K., Yamamoto, M., Bunk, O., Wang, M.
Deposit date:2018-11-13
Release date:2019-03-13
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Long-wavelength native-SAD phasing: opportunities and challenges
To Be Published
6IMM
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CRYO-EM STRUCTURE OF AN ALPHAVIRUS, SINDBIS VIRUS
Descriptor:Spike glycoprotein E1, Spike glycoprotein E2, Assembly protein E3, ...
Authors:Zhang, X., Ma, J., Chen, L.
Deposit date:2018-10-23
Release date:2019-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Implication for alphavirus host-cell entry and assembly indicated by a 3.5 angstrom resolution cryo-EM structure.
Nat Commun, 9, 2018
5ZO1
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CRYSTAL STRUCTURE OF MOUSE NECTIN-LIKE MOLECULE 4 (MNECL-4) FULL ECTODOMAIN (IG1-IG3), 2.2A
Descriptor:Cell adhesion molecule 4, ALPHA-L-FUCOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Liu, X., An, T., Li, D., Fan, Z., Xiang, P., Li, C., Ju, W., Li, J., Hu, G., Qin, B., Yin, B., Wojdyla, J.A., Wang, M., Yuan, J., Qiang, B., Shu, P., Cui, S., Peng, X.
Deposit date:2018-04-12
Release date:2019-01-30
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5ZO2
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CRYSTAL STRUCTURE OF MOUSE NECTIN-LIKE MOLECULE 4 (MNECL-4) FULL ECTODOMAIN IN COMPLEX WITH MOUSE NECTIN-LIKE MOLECULE 1 (MNECL-1) IG1 DOMAIN, 3.3A
Descriptor:Cell adhesion molecule 4, Cell adhesion molecule 3, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Liu, X., An, T., Li, D., Fan, Z., Xiang, P., Li, C., Ju, W., Li, J., Hu, G., Qin, B., Yin, B., Wojdyla, J.A., Wang, M., Yuan, J., Qiang, B., Shu, P., Cui, S., Peng, X.
Deposit date:2018-04-12
Release date:2019-01-30
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Structure of the heterophilic interaction between the nectin-like 4 and nectin-like 1 molecules.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6IFO
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CRYSTAL STRUCTURE OF ACRIIA2-SPYCAS9-SGRNA TERNARY COMPLEX
Descriptor:CRISPR-associated endonuclease Cas9/Csn1, RNA (99-MER), AcrIIA2
Authors:Liu, L., Wang, Y.
Deposit date:2018-09-20
Release date:2019-01-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.313 Å)
Cite:Phage AcrIIA2 DNA Mimicry: Structural Basis of the CRISPR and Anti-CRISPR Arms Race.
Mol. Cell, 73, 2019
5Z3W
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MALATE DEHYDROGENASE BINDS SILVER AT C113
Descriptor:Malate dehydrogenase, SILVER ION
Authors:Wang, H., Wang, M., Sun, H.
Deposit date:2018-01-09
Release date:2019-01-16
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structure of silver-bound malate dehydrogenase
To Be Published
6EDQ
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CRYSTAL STRUCTURE OF THE LIGHT-GATED ANION CHANNELRHODOPSIN GTACR1
Descriptor:Anion channelrhodopsin 1, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLYCEROL
Authors:Li, H., Huang, C.Y., Wang, M., Zheng, L., Spudich, J.L.
Deposit date:2018-08-10
Release date:2019-01-16
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a natural light-gated anion channelrhodopsin.
Elife, 8, 2019
5QII
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CRYSTAL STRUCTURE OF 11BETA-HSD1 DOUBLE MUTANT (L262R, F278E) COMPLEXED WITH 2-(3-(1-(4-CHLOROPHENYL)CYCLOPROPYL) -[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-8-YL)PROPAN-2-OL
Descriptor:Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-{3-[1-(4-chlorophenyl)cyclopropyl][1,2,4]triazolo[4,3-a]pyridin-8-yl}propan-2-ol
Authors:Sheriff, S.
Deposit date:2018-07-03
Release date:2018-12-19
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Discovery of Clinical Candidate BMS-823778 as an Inhibitor of Human 11 beta-Hydroxysteroid Dehydrogenase Type 1 (11 beta-HSD-1).
ACS Med Chem Lett, 9, 2018
5QIJ
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CRYSTAL STRUCTURE OF MURINE 11B- HYDROXYSTEROIDDEHYDROGENASE COMPLEXED WITH 2-(3-(1-(4- CHLOROPHENYL)CYCLOPROPYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-8- YL)PROPAN-2-OL
Descriptor:Corticosteroid 11-beta-dehydrogenase isozyme 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 2-{3-[1-(4-chlorophenyl)cyclopropyl][1,2,4]triazolo[4,3-a]pyridin-8-yl}propan-2-ol, ...
Authors:Sheriff, S.
Deposit date:2018-07-03
Release date:2018-12-19
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery of Clinical Candidate BMS-823778 as an Inhibitor of Human 11 beta-Hydroxysteroid Dehydrogenase Type 1 (11 beta-HSD-1).
ACS Med Chem Lett, 9, 2018
6IFK
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CRYO-EM STRUCTURE OF TYPE III-A CSM-CTR1 COMPLEX, AMPPNP BOUND
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFL
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CRYO-EM STRUCTURE OF TYPE III-A CSM-NTR COMPLEX
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.16 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFN
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CRYSTAL STRUCTURE OF TYPE III-A CRISPR CSM COMPLEX
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated RAMP protein Csm3, Type III-A CRISPR-associated RAMP protein Csm4, ...
Authors:You, L., Wang, J., Wang, Y.
Deposit date:2018-09-20
Release date:2018-12-12
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFR
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-NTR, ATP BOUND
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFU
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CRYO-EM STRUCTURE OF TYPE III-A CSM-CTR2-DSDNA COMPLEX
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFY
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-CTR1
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IFZ
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-CTR2-SSDNA COMPLEX
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.58 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
6IG0
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TYPE III-A CSM COMPLEX, CRYO-EM STRUCTURE OF CSM-CTR1, ATP BOUND
Descriptor:Type III-A CRISPR-associated protein Csm1, Type III-A CRISPR-associated protein Csm2, Type III-A CRISPR-associated RAMP protein Csm3, ...
Authors:You, L., Ma, J., Wang, J., Zhang, X., Wang, Y.
Deposit date:2018-09-21
Release date:2018-12-12
Last modified:2019-01-23
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Structure Studies of the CRISPR-Csm Complex Reveal Mechanism of Co-transcriptional Interference
Cell, 176, 2019
5ZTE
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CRYSTAL STRUCTURE OF PRXA C119S MUTANT FROM ARABIDOPSIS THALIANA
Descriptor:2-Cys peroxiredoxin BAS1, chloroplastic
Authors:Yang, Y., Cai, W., Wang, J., Pan, W., Liu, L., Wang, M., Zhang, M.
Deposit date:2018-05-03
Release date:2018-10-10
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of Arabidopsis thaliana peroxiredoxin A C119S mutant.
Acta Crystallogr F Struct Biol Commun, 74, 2018
6FMT
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IMISX-EP OF HG-BACA SOAKING SAD
Descriptor:Undecaprenyl-diphosphatase, MERCURY (II) ION, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-09-05
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018
6FMV
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IMISX-EP OF HG-BACA SOAKING SIRAS
Descriptor:Undecaprenyl-diphosphatase, CITRATE ANION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-09-05
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018
6FMW
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IMISX-EP OF HG-BACA COCRYSTALLIZATION
Descriptor:Undecaprenyl-diphosphatase, MERCURY (II) ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-09-05
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018
6FMX
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IMISX-EP OF W-PGPB
Descriptor:Phosphatidylglycerophosphatase B, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, TUNGSTATE(VI)ION
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-09-05
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018
6FMY
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IMISX-EP OF S-PEPTST
Descriptor:Di-or tripeptide:H+ symporter, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ...
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-09-05
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018
6FMR
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IMISX-EP OF SE-PEPTST
Descriptor:Di-or tripeptide:H+ symporter, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, PHOSPHATE ION
Authors:Huang, C.-Y., Olieric, V., Howe, N., Warshamanage, R., Weinert, T., Panepucci, E., Vogeley, L., Basu, S., Diederichs, K., Caffrey, M., Wang, M.
Deposit date:2018-02-02
Release date:2018-08-29
Last modified:2018-10-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:In situ serial crystallography for rapid de novo membrane protein structure determination.
Commun Biol, 1, 2018