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3MDD
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CRYSTAL STRUCTURES OF MEDIUM CHAIN ACYL-COA DEHYDROGENASE FROM PIG LIVER MITOCHONDRIA WITH AND WITHOUT SUBSTRATE
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Kim, J.-J.P., Wang, M., Paschke, R.
Deposit date:1994-07-13
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate.
Proc.Natl.Acad.Sci.USA, 90, 1993
3MDE
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CRYSTAL STRUCTURES OF MEDIUM CHAIN ACYL-COA DEHYDROGENASE FROM PIG LIVER MITOCHONDRIA WITH AND WITHOUT SUBSTRATE
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, OCTANOYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Kim, J.-J.P., Wang, M., Paschke, R.
Deposit date:1994-07-13
Release date:1994-09-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate.
Proc.Natl.Acad.Sci.USA, 90, 1993
1SNB
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STRUCTURE OF SCORPION NEUROTOXIN BMK M8
Descriptor:NEUROTOXIN BMK M8
Authors:Wang, D.C., Zeng, Z.H., Li, H.M.
Deposit date:1997-03-12
Release date:1997-05-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of an acidic neurotoxin from scorpion Buthus martensii Karsch at 1.85 A resolution.
J.Mol.Biol., 261, 1996
1EGD
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STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Lee, H.J., Wang, M., Paschke, R., Nandy, A., Ghisla, S., Kim, J.P.
Deposit date:1996-04-11
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.
Biochemistry, 35, 1996
1EGE
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STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Lee, H.J., Wang, M., Paschke, R., Nandy, A., Ghisla, S., Kim, J.P.
Deposit date:1996-04-11
Release date:1997-06-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.
Biochemistry, 35, 1996
1HFZ
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ALPHA-LACTALBUMIN
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Pike, A.C.W., Brew, K., Acharya, K.R.
Deposit date:1996-06-13
Release date:1997-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of guinea-pig, goat and bovine alpha-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase.
Structure, 4, 1996
1EGC
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STRUCTURE OF T255E, E376G MUTANT OF HUMAN MEDIUM CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH OCTANOYL-COA
Descriptor:MEDIUM CHAIN ACYL-COA DEHYDROGENASE, OCTANOYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Lee, H.J., Wang, M., Paschke, R., Nandy, A., Ghisla, S., Kim, J.P.
Deposit date:1996-04-11
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of the wild type and the Glu376Gly/Thr255Glu mutant of human medium-chain acyl-CoA dehydrogenase: influence of the location of the catalytic base on substrate specificity.
Biochemistry, 35, 1996
1IVH
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STRUCTURE OF HUMAN ISOVALERYL-COA DEHYDROGENASE AT 2.6 ANGSTROMS RESOLUTION: STRUCTURAL BASIS FOR SUBSTRATE SPECIFICITY
Descriptor:ISOVALERYL-COA DEHYDROGENASE, FLAVIN-ADENINE DINUCLEOTIDE, COENZYME A PERSULFIDE
Authors:Tiffany, K.A., Roberts, D.L., Wang, M., Paschke, R., Mohsen, A.-W.A., Vockley, J., Kim, J.J.P.
Deposit date:1997-05-15
Release date:1998-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of human isovaleryl-CoA dehydrogenase at 2.6 A resolution: structural basis for substrate specificity,.
Biochemistry, 36, 1997
1AMO
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THREE-DIMENSIONAL STRUCTURE OF NADPH-CYTOCHROME P450 REDUCTASE: PROTOTYPE FOR FMN-AND FAD-CONTAINING ENZYMES
Descriptor:NADPH-CYTOCHROME P450 REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, ...
Authors:Wang, M., Roberts, D.L., Paschke, R., Shea, T.M., Masters, B.S.S., Kim, J.J.P.
Deposit date:1997-06-17
Release date:1998-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Three-dimensional structure of NADPH-cytochrome P450 reductase: prototype for FMN- and FAD-containing enzymes.
Proc.Natl.Acad.Sci.USA, 94, 1997
1A4V
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ALPHA-LACTALBUMIN
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Chandra, N., Acharya, K.R.
Deposit date:1998-02-05
Release date:1999-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural evidence for the presence of a secondary calcium binding site in human alpha-lactalbumin.
Biochemistry, 37, 1998
1SN1
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STRUCTURE OF SCORPION NEUROTOXIN BMK M1
Descriptor:PROTEIN (NEUROTOXIN BMK M1)
Authors:He, X.L., Li, H.M., Liu, X.Q., Zeng, Z.H., Wang, D.C.
Deposit date:1998-11-12
Release date:1999-11-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channel.
J.Mol.Biol., 292, 1999
1SN4
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STRUCTURE OF SCORPION NEUROTOXIN BMK M4
Descriptor:PROTEIN (NEUROTOXIN BMK M4), ACETATE ION
Authors:He, X.L., Li, H.M., Liu, X.Q., Zeng, Z.H., Wang, D.C.
Deposit date:1998-11-11
Release date:1999-11-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structures of two alpha-like scorpion toxins: non-proline cis peptide bonds and implications for new binding site selectivity on the sodium channel.
J.Mol.Biol., 292, 1999
1CHZ
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A NEW NEUROTOXIN FROM BUTHUS MARTENSII KARSCH
Descriptor:PROTEIN (BMK M2), CHLORIDE ION
Authors:He, X.L., Deng, J.P., Li, H.M., Wang, D.C.
Deposit date:1999-03-31
Release date:2000-03-31
Last modified:2014-04-09
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structure of a new neurotoxin from the scorpion Buthus martensii Karsch at 1.76 A.
Acta Crystallogr.,Sect.D, 56, 2000
1DJT
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ATOMIC RESOLUTION STRUCTURE OF SCORPION ALPHA-LIKE TOXIN BMK M1 IN A NEW CRYSTAL FORM
Descriptor:ALPHA-LIKE NEUROTOXIN BMK M1
Authors:Wang, D.-C., He, X.-L.
Deposit date:1999-12-05
Release date:2000-12-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Atomic Resolution Structure of Scorpion Alpha-Like Toxin BmK M1 in a New Crystal Form
To be Published
1JQI
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CRYSTAL STRUCTURE OF RAT SHORT CHAIN ACYL-COA DEHYDROGENASE COMPLEXED WITH ACETOACETYL-COA
Descriptor:short chain acyl-CoA dehydrogenase, ACETOACETYL-COENZYME A, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Battaile, K.P., Molin-Case, J., Paschke, R., Wang, M., Bennett, D., Vockley, J., Kim, J.-J.P.
Deposit date:2001-08-07
Release date:2002-02-13
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure of rat short chain acyl-CoA dehydrogenase complexed with acetoacetyl-CoA: comparison with other acyl-CoA dehydrogenases.
J.Biol.Chem., 277, 2002
1KVK
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THE STRUCTURE OF BINARY COMPLEX BETWEEN A MAMMALIAN MEVALONATE KINASE AND ATP: INSIGHTS INTO THE REACTION MECHANISM AND HUMAN INHERITED DISEASE
Descriptor:mevalonate kinase, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE
Authors:Fu, Z., Wang, M., Potter, D., Mizioko, H.M., Kim, J.J.
Deposit date:2002-01-26
Release date:2002-03-27
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structure of a Binary complex between a Mammalian Mevalonate Kinase and ATP: Insights into the Reaction Mechanism and Human Inherited Disease
J.Biol.Chem., 277, 2002
1NIY
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THREE DIMENSIONAL SOLUTION STRUCTURE OF HAINANTOXIN-IV BY 2D 1H-NMR
Descriptor:HAINANTOXIN-IV
Authors:Li, D., Lu, S., Gu, X., Liang, S.
Deposit date:2002-12-30
Release date:2003-01-14
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Structure-Activity Relationships of Hainantoxin-IV and Structure Determination of Active and Inactive Sodium Channel Blockers.
J.Biol.Chem., 279, 2004
1NHU
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HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR
Descriptor:HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE, (2S)-2-[(2,4-DICHLORO-BENZOYL)-(3-TRIFLUOROMETHYL-BENZYL)-AMINO]-3-PHENYL-PROPIONIC ACID
Authors:Wang, M., Ng, K.K.S., Cherney, M.M., Chan, L., Yannopoulos, C.G., Bedard, J., Morin, N., Nguyen-Ba, N., Alaoui-Ismaili, M.H., Bethell, R.C., James, M.N.G.
Deposit date:2002-12-19
Release date:2003-03-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Non-Nucleoside Analogue Inhibitors Bind to an Allosteric Site on HCV NS5B Polymerase: Crystal Structures and Mechanism of Inhibition
J.Biol.Chem., 278, 2003
1NHV
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HEPATITIS C VIRUS RNA POLYMERASE IN COMPLEX WITH NON-NUCLEOSIDE ANALOGUE INHIBITOR
Descriptor:HEPATITIS C VIRUS NS5B RNA-DEPENDENT RNA POLYMERASE, (2S)-2-[(5-BENZOFURAN-2-YL-THIOPHEN-2-YLMETHYL)-(2,4-DICHLORO-BENZOYL)-AMINO]-3-PHENYL-PROPIONIC ACID
Authors:Wang, M., Ng, K.K.S., Cherney, M.M., Chan, L., Yannopoulos, C.G., Bedard, J., Morin, N., Nguyen-Ba, N., Alaoui-Ismaili, M.H., Bethell, R.C., James, M.N.G.
Deposit date:2002-12-19
Release date:2003-03-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Non-Nucleoside Analogue Inhibitors Bind to an Allosteric Site on HCV NS5B Polymerase: Crystal Structures and Mechanism of Inhibition
J.Biol.Chem., 278, 2003
1LI4
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HUMAN S-ADENOSYLHOMOCYSTEINE HYDROLASE COMPLEXED WITH NEPLANOCIN
Descriptor:S-adenosylhomocysteine hydrolase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-CYCLOPENTANE-1,2-DIOL, ...
Authors:Yang, X., Hu, Y., Yin, D.H., Turner, M.A., Wang, M., Borchardt, R.T., Howell, P.L., Kuczera, K., Schowen, R.L.
Deposit date:2002-04-17
Release date:2003-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Catalytic strategy of S-adenosyl-L-homocysteine hydrolase: Transition-state stabilization and the avoidance of abortive reactions
Biochemistry, 42, 2003
1KV0
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CIS/TRANS ISOMERIZATION OF NON-PROLYL PEPTIDE BOND OBSERVED IN CRYSTAL STRUCTURE OF AN SCORPION TOXIN
Descriptor:Alpha-like toxin BmK-M7
Authors:Guan, R.J., He, X.L., Wang, M., Xiang, Y., Wang, D.C.
Deposit date:2002-01-23
Release date:2003-09-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural mechanism governing cis and trans isomeric states and an intramolecular switch for cis/trans isomerization of a non-proline peptide bond observed in crystal structures of scorpion toxins.
J.Mol.Biol., 341, 2004
1RYG
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THREE DIMENSIONAL SOLUTION STRUCTURE OF THE R29A MUTANT OF SODIUM CHANNELS INHIBITOR HAINANTOXIN-IV BY 2D 1H-NMR
Descriptor:Hainantoxin-IV
Authors:Li, D., Lu, S., Gu, X., Liang, S.
Deposit date:2003-12-22
Release date:2004-01-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure--activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers
J.Biol.Chem., 279, 2004
1RYV
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THREE DIMENSIONAL SOLUTION STRUCTURE OF THE K27A MUTANT OF SODIUM CHANNELS INHIBITOR HAINANTOXIN-IV BY 2D 1H-NMR
Descriptor:Hainantoxin-IV
Authors:Li, D., Lu, S., Gu, X., Liang, S.
Deposit date:2003-12-22
Release date:2004-01-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure--activity relationships of hainantoxin-IV and structure determination of active and inactive sodium channel blockers
J.Biol.Chem., 279, 2004
1SIQ
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THE CRYSTAL STRUCTURE AND MECHANISM OF HUMAN GLUTARYL-COA DEHYDROGENASE
Descriptor:Glutaryl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Wang, M., Fu, Z., Paschke, R., Goodman, S., Frerman, F.E., Kim, J.J.
Deposit date:2004-03-01
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structures of Human Glutaryl-CoA Dehydrogenase with and without an Alternate Substrate: Structural Bases of Dehydrogenation and Decarboxylation Reactions
Biochemistry, 43, 2004
1SIR
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THE CRYSTAL STRUCTURE AND MECHANISM OF HUMAN GLUTARYL-COA DEHYDROGENASE
Descriptor:Glutaryl-CoA dehydrogenase, FLAVIN-ADENINE DINUCLEOTIDE, S-4-NITROBUTYRYL-COA
Authors:Wang, M., Fu, Z., Paschke, R., Goodman, S.L., Frerman, F.E., Kim, J.J.
Deposit date:2004-03-01
Release date:2004-09-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structures of Human Glutaryl-CoA Dehydrogenase with and without an Alternate Substrate: Structural Bases of Dehydrogenation and Decarboxylation Reactions
Biochemistry, 43, 2004