Author results

4M7C
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CRYSTAL STRUCTURE OF THE TRF2-BINDING MOTIF OF SLX4 IN COMPLEX WITH THE TRFH DOMAIN OF TRF2
分子名称:Telomeric repeat-binding factor 2, Peptide from Structure-specific endonuclease subunit SLX4
著者Wan, B., Chen, Y., Wu, J., Liu, Y., Lei, M.
登録日2013-08-12
公開日2013-09-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres
Cell Rep, 4, 2013
4ZOU
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CRYSTAL STRUCTURE OF THE BTB DOMAIN OF SLX4
分子名称:Structure-specific endonuclease subunit SLX4
著者Wan, B., Chen, Y., Wu, J., Liu, Y., Lei, M.
登録日2015-05-07
公開日2016-05-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The BTB domain is both a structural and functional pivot of the SLX4-nuclease complex
to be published
5DOF
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CRYSTAL STRUCTURE OF TETRAHYMENA P19
分子名称:Telomerase-associated protein 19
著者Wan, B., Tang, T., Wu, J., Lei, M.
登録日2015-09-11
公開日2015-11-25
最終更新日2015-12-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex.
Nat.Struct.Mol.Biol., 22, 2015
5DOI
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CRYSTAL STRUCTURE OF TETRAHYMENA P45N AND P19
分子名称:Telomerase-associated protein 19, Telomerase associated protein p45
著者Wan, B., Tang, T., Wu, J., Lei, M.
登録日2015-09-11
公開日2015-11-25
最終更新日2015-12-23
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex
Nat.Struct.Mol.Biol., 22, 2015
5DOK
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CRYSTAL STRUCTURE OF TETRAHYMENA P45C
分子名称:Telomerase associated protein p45, MAGNESIUM ION
著者Wan, B., Tang, T., Wu, J., Lei, M.
登録日2015-09-11
公開日2015-11-25
最終更新日2015-12-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Tetrahymena telomerase p75-p45-p19 subcomplex is a unique CST complex
Nat.Struct.Mol.Biol., 22, 2015
6J0V
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CRYSTAL STRUCTURE OF YEAST RTT107
分子名称:Regulator of Ty1 transposition protein 107
著者Wan, B., Wu, J., Lei, M.
登録日2018-12-27
公開日2019-08-14
実験手法X-RAY DIFFRACTION (2.314 Å)
主引用文献The molecular mechanism of tetra-BRCT and multi-client interactions and its broad impact on genome functions
To be published
6J0W
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CRYSTAL STRUCTURE OF YEAST RTT107 AND NSE6
分子名称:Regulator of Ty1 transposition protein 107, Peptide from DNA repair protein KRE29
著者Wan, B., Wu, J., Lei, M.
登録日2018-12-27
公開日2019-08-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The molecular mechanism of tetra-BRCT and multi-client interactions and its broad impact on genome functions
To be published
6J0X
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CRYSTAL STRUCTURE OF YEAST RTT107 AND MMS22
分子名称:Regulator of Ty1 transposition protein 107, Peptide from E3 ubiquitin-protein ligase substrate receptor MMS22
著者Wan, B., Wu, J., Lei, M.
登録日2018-12-27
公開日2019-08-14
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献The molecular mechanism of tetra-BRCT and multi-client interactions and its broad impact on genome functions
To be published
6J0Y
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CRYSTAL STRUCTURE OF YEAST RTT107 AND SLX4
分子名称:Regulator of Ty1 transposition protein 107, Peptide from Structure-specific endonuclease subunit SLX4
著者Wan, B., Wu, J., Lei, M.
登録日2018-12-27
公開日2019-08-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The molecular mechanism of tetra-BRCT and multi-client interactions and its broad impact on genome functions
To be published
3U84
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CRYSTAL STRUCTURE OF HUMAN MENIN
分子名称:Menin
著者Huang, J., Wan, B., Lei, M.
登録日2011-10-15
公開日2012-02-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
3U85
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CRYSTAL STRUCTURE OF HUMAN MENIN IN COMPLEX WITH MLL1
分子名称:Menin, Histone-lysine N-methyltransferase 2A
著者Huang, J., Wan, B., Lei, M.
登録日2011-10-15
公開日2012-02-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
3U86
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CRYSTAL STRUCTURE OF HUMAN MENIN IN COMPLEX WITH JUND
分子名称:Menin, Transcription factor jun-D
著者Huang, J., Wan, B., Lei, M.
登録日2011-10-15
公開日2012-02-15
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (2.843 Å)
主引用文献The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
3U88
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CRYSTAL STRUCTURE OF HUMAN MENIN IN COMPLEX WITH MLL1 AND LEDGF
分子名称:Menin, Histone-lysine N-methyltransferase 2A, Lens epithelium-derived growth factor, ...
著者Huang, J., Wan, B., Lei, M.
登録日2011-10-16
公開日2012-02-15
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature, 482, 2012
3RSN
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CRYSTAL STRUCTURE OF THE N-TERMINAL REGION OF HUMAN ASH2L
分子名称:Set1/Ash2 histone methyltransferase complex subunit ASH2, ZINC ION
著者Chen, Y., Wan, B., Wang, K.C., Cao, F., Yang, Y., Protacio, A., Dou, Y., Chang, H.Y., Lei, M.
登録日2011-05-02
公開日2011-06-22
最終更新日2011-12-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the N-terminal region of human Ash2L shows a winged-helix motif involved in DNA binding.
Embo Rep., 12, 2011
3TOJ
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STRUCTURE OF THE SPRY DOMAIN OF HUMAN ASH2L
分子名称:Set1/Ash2 histone methyltransferase complex subunit ASH2
著者Chen, Y., Cao, F., Wan, B., Dou, Y., Lei, M.
登録日2011-09-05
公開日2012-01-25
最終更新日2017-08-23
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structure of the SPRY domain of human Ash2L and its interactions with RbBP5 and DPY30.
Cell Res., 22, 2012
2OJU
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X-RAY STRUCTURE OF COMPLEX OF HUMAN CYCLOPHILIN J WITH CYCLOSPORIN A
分子名称:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3, CYCLOSPORIN A
著者Xia, Z., Huang, L.
登録日2007-01-14
公開日2008-01-22
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Targeting Cyclophilin J, a Novel Peptidyl-Prolyl Isomerase, Can Induce Cellular G1/S Arrest and Repress the Growth of Hepatocellular Carcinoma
To be Published
2OK3
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X-RAY STRUCTURE OF HUMAN CYCLOPHILIN J AT 2.0 ANGSTROM
分子名称:Peptidyl-prolyl cis-trans isomerase-like 3, NICKEL (II) ION
著者Xia, Z.
登録日2007-01-15
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Targeting Cyclophilin J, a novel peptidyl-prolyl isomerase, can induce cellular G1/S arrest and repress the growth of Hepatocellular carcinoma
To be Published
3PKA
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M. TUBERCULOSIS METAP WITH BENGAMIDE ANALOG Y02, IN MN FORM
分子名称:Methionine aminopeptidase, MANGANESE (II) ION, (2R,3R,4S,5R,6E)-3,4,5-trihydroxy-2-methoxy-8,8-dimethyl-N-[2-(2,4,6-trimethylphenoxy)ethyl]non-6-enamide, ...
著者Ye, Q.Z., Lu, J.P.
登録日2010-11-11
公開日2011-04-20
最終更新日2013-05-29
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
Chemmedchem, 6, 2011
3PKB
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M. TUBERCULOSIS METAP WITH BENGAMIDE ANALOG Y16, IN MN FORM
分子名称:Methionine aminopeptidase, (E,2R,3R,4S,5R)-N-(2-azanyl-2-oxidanylidene-ethyl)-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, MANGANESE (II) ION, ...
著者Ye, Q.Z., Lu, J.P.
登録日2010-11-11
公開日2011-04-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
Chemmedchem, 6, 2011
3PKC
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M. TUBERCULOSIS METAP WITH BENGAMIDE ANALOG Y08, IN MN FORM
分子名称:Methionine aminopeptidase, MANGANESE (II) ION, (E,2R,3R,4S,5R)-N-[[(3S)-1-cyclopropylcarbonylpiperidin-3-yl]methyl]-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide
著者Ye, Q.Z., Lu, J.P.
登録日2010-11-11
公開日2011-04-20
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
Chemmedchem, 6, 2011
3PKD
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M. TUBERCULOSIS METAP WITH BENGAMIDE ANALOG Y10, IN MN FORM
分子名称:Methionine aminopeptidase, MANGANESE (II) ION, (E,2R,3R,4S,5R)-N-(2,3-dihydro-1H-inden-2-yl)-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide
著者Ye, Q.Z., Lu, J.P.
登録日2010-11-11
公開日2011-04-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
Chemmedchem, 6, 2011
3PKE
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M. TUBERCULOSIS METAP WITH BENGAMIDE ANALOG Y10, IN NI FORM
分子名称:Methionine aminopeptidase, (E,2R,3R,4S,5R)-N-(2,3-dihydro-1H-inden-2-yl)-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, NICKEL (II) ION, ...
著者Ye, Q.Z., Lu, J.P.
登録日2010-11-11
公開日2011-04-20
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
Chemmedchem, 6, 2011
4DNC
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CRYSTAL STRUCTURE OF HUMAN MOF IN COMPLEX WITH MSL1
分子名称:Histone acetyltransferase KAT8, Male-specific lethal 1 homolog, ZINC ION
著者Huang, J., Lei, M.
登録日2012-02-08
公開日2012-07-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structural insight into the regulation of MOF in the male-specific lethal complex and the non-specific lethal complex.
Cell Res., 22, 2012
5AGR
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CRYSTAL STRUCTURE OF THE LEURS EDITING DOMAIN OF MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH THE ADDUCT (S)-3-(AMINOMETHYL)-7-ETHOXYBENZO[C][1,2]OXABOROL-1(3H)-OL-AMP
分子名称:LEUCINE--TRNA LIGASE, METHIONINE, LEUCINE, ...
著者Palencia, A., Li, X., Alley, M.R.K., Ding, C., Easom, E.E., Hernandez, V., Meewan, M., Mohan, M., Rock, F.L., Franzblau, S.G., Wang, Y., Lenaerts, A.J., Parish, T., Cooper, C.B., Waters, M.G., Ma, Z., Mendoza, A., Barros, D., Cusack, S., Plattner, J.J.
登録日2015-02-03
公開日2016-03-02
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium Tuberculosis that Target Leucyl-tRNA Synthetase.
Antimicrob.Agents Chemother., 60, 2016
5AGS
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CRYSTAL STRUCTURE OF THE LEURS EDITING DOMAIN OF MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH THE ADDUCT 3-(AMINOMETHYL)-4-BROMO-7-ETHOXYBENZO[C][1,2]OXABOROL-1(3H)-OL-AMP
分子名称:LEUCYL-TRNA SYNTHETASE, METHIONINE, 3-(AMINOMETHYL)-4-BROMO-7-ETHOXYBENZO[C][1,2]OXABOROL-1(3H)-OL-MODIFIED ADENOSINE
著者Palencia, A., Li, X., Alley, M.R.K., Ding, C., Easom, E.E., Hernandez, V., Meewan, M., Mohan, M., Rock, F.L., Franzblau, S.G., Wang, Y., Lenaerts, A.J., Parish, T., Cooper, C.B., Waters, M.G., Ma, Z., Mendoza, A., Barros, D., Cusack, S., Plattner, J.J.
登録日2015-02-03
公開日2016-03-09
最終更新日2017-08-09
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium Tuberculosis that Target Leucyl-tRNA Synthetase.
Antimicrob.Agents Chemother., 60, 2016
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