Author results

4GNZ
  • Download 4gnz
  • View 4gnz
Molmil generated image of 4gnz
CRYSTAL STRUCTURE OF THE C707S MUTANT OF C-TERMINAL DOMAIN OF 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH NADP
Descriptor:Cytosolic 10-formyltetrahydrofolate dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ...
Authors:Tsybovsky, Y.
Deposit date:2012-08-17
Release date:2013-01-23
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1.
Chem.Biol.Interact, 202, 2013
4GO0
  • Download 4go0
  • View 4go0
Molmil generated image of 4go0
CRYSTAL STRUCTURE OF THE C707S MUTANT OF C-TERMINAL DOMAIN OF 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH NADPH
Descriptor:Cytosolic 10-formyltetrahydrofolate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Tsybovsky, Y.
Deposit date:2012-08-17
Release date:2013-01-23
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (3.38 Å)
Cite:The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1.
Chem.Biol.Interact, 202, 2013
4GO2
  • Download 4go2
  • View 4go2
Molmil generated image of 4go2
CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH THIO-NADP
Descriptor:Cytosolic 10-formyltetrahydrofolate dehydrogenase, SULFATE ION, GLYCEROL, ...
Authors:Tsybovsky, Y.
Deposit date:2012-08-18
Release date:2013-01-23
Last modified:2013-05-22
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:The mechanism of discrimination between oxidized and reduced coenzyme in the aldehyde dehydrogenase domain of Aldh1l1.
Chem.Biol.Interact, 202, 2013
2O2P
  • Download 2o2p
  • View 2o2p
Molmil generated image of 2o2p
CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE
Descriptor:Formyltetrahydrofolate dehydrogenase, SULFATE ION, GLYCEROL
Authors:Tsybovsky, Y., Donato, H., Krupenko, N.I., Davies, C., Krupenko, S.A.
Deposit date:2006-11-30
Release date:2007-03-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Biochemistry, 46, 2007
2O2Q
  • Download 2o2q
  • View 2o2q
Molmil generated image of 2o2q
CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH NADP
Descriptor:Formyltetrahydrofolate dehydrogenase, MAGNESIUM ION, SULFATE ION, ...
Authors:Tsybovsky, Y., Donato, H., Krupenko, N.I., Davies, C., Krupenko, S.A.
Deposit date:2006-11-30
Release date:2007-03-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Biochemistry, 46, 2007
2O2R
  • Download 2o2r
  • View 2o2r
Molmil generated image of 2o2r
CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH NADPH
Descriptor:Formyltetrahydrofolate dehydrogenase, SULFATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Tsybovsky, Y., Donato, H., Krupenko, N.I., Davies, C., Krupenko, S.A.
Deposit date:2006-11-30
Release date:2007-03-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases.
Biochemistry, 46, 2007
3RHJ
  • Download 3rhj
  • View 3rhj
Molmil generated image of 3rhj
CRYSTAL STRUCTURE OF THE E673A MUTANT OF THE C-TERMINAL DOMAIN OF RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH CO-PURIFIED NADP
Descriptor:Aldehyde dehydrogenase 1 family, member L1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Tsybovsky, Y.
Deposit date:2011-04-11
Release date:2011-04-27
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
3RHL
  • Download 3rhl
  • View 3rhl
Molmil generated image of 3rhl
CRYSTAL STRUCTURE OF THE E673A/C707A DOUBLE MUTANT OF THE C-TERMINAL DOMAIN OF RAT 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH CO-PURIFIED NADP
Descriptor:Aldehyde dehydrogenase 1 family, member L1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Tsybovsky, Y.
Deposit date:2011-04-11
Release date:2011-04-27
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
3RHM
  • Download 3rhm
  • View 3rhm
Molmil generated image of 3rhm
CRYSTAL STRUCTURE OF THE E673Q MUTANT OF C-TERMINAL DOMAIN OF 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE
Descriptor:Aldehyde dehydrogenase 1 family, member L1, SULFATE ION, ...
Authors:Tsybovsky, Y.
Deposit date:2011-04-11
Release date:2011-04-27
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
3RHO
  • Download 3rho
  • View 3rho
Molmil generated image of 3rho
CRYSTAL STRUCTURE OF THE E673Q MUTANT OF C-TERMINAL DOMAIN OF 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH NADP
Descriptor:Aldehyde dehydrogenase 1 family, member L1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Tsybovsky, Y.
Deposit date:2011-04-11
Release date:2011-04-27
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
3RHP
  • Download 3rhp
  • View 3rhp
Molmil generated image of 3rhp
CRYSTAL STRUCTURE OF THE C707A MUTANT OF THE C-TERMINAL DOMAIN OF 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE
Descriptor:Aldehyde dehydrogenase 1 family, member L1, SULFATE ION, ...
Authors:Tsybovsky, Y.
Deposit date:2011-04-11
Release date:2011-05-04
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
3RHQ
  • Download 3rhq
  • View 3rhq
Molmil generated image of 3rhq
CRYSTAL STRUCTURE OF THE C707A MUTANT OF C-TERMINAL DOMAIN OF 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH NADP
Descriptor:Aldehyde dehydrogenase 1 family, member L1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Tsybovsky, Y.
Deposit date:2011-04-12
Release date:2011-05-04
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
3RHR
  • Download 3rhr
  • View 3rhr
Molmil generated image of 3rhr
CRYSTAL STRUCTURE OF THE C707A MUTANT OF THE C-TERMINAL DOMAIN OF 10'FORMYLTETRAHYDROFOLATE DEHYDROGENASE IN COMPLEX WITH NADPH
Descriptor:Aldehyde dehydrogenase 1 family, member L1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Tsybovsky, Y.
Deposit date:2011-04-12
Release date:2011-04-27
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conserved catalytic residues of the ALDH1L1 aldehyde dehydrogenase domain control binding and discharging of the coenzyme.
J.Biol.Chem., 286, 2011
5ILG
  • Download 5ilg
  • View 5ilg
Molmil generated image of 5ilg
CRYSTAL STRUCTURE OF PHOTORECEPTOR DEHYDROGENASE FROM DROSOPHILA MELANOGASTER
Descriptor:Photoreceptor dehydrogenase, isoform C, MAGNESIUM ION, ...
Authors:Hofmann, L., Tsybovsky, Y., Banerjee, S.
Deposit date:2016-03-04
Release date:2016-11-16
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family.
Biochemistry, 55, 2016
5ILO
  • Download 5ilo
  • View 5ilo
Molmil generated image of 5ilo
CRYSTAL STRUCTURE OF PHOTORECEPTOR DEHYDROGENASE FROM DROSOPHILA MELANOGASTER
Descriptor:Photoreceptor dehydrogenase, isoform C, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Hofmann, L., Tsybovsky, Y., Banerjee, S.
Deposit date:2016-03-04
Release date:2016-11-16
Last modified:2018-04-25
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Structural Insights into the Drosophila melanogaster Retinol Dehydrogenase, a Member of the Short-Chain Dehydrogenase/Reductase Family.
Biochemistry, 55, 2016
6XLU
  • Download 6xlu
  • View 6xlu
Molmil generated image of 6xlu
STRUCTURE OF SARS-COV-2 SPIKE AT PH 4.0
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Zhou, T., Tsybovsky, Y., Olia, A., Kwong, P.D.
Deposit date:2020-06-29
Release date:2020-08-12
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains
Biorxiv, 2020
6XM0
  • Download 6xm0
  • View 6xm0
Molmil generated image of 6xm0
CONSENSUS STRUCTURE OF SARS-COV-2 SPIKE AT PH 5.5
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Zhou, T., Tsybovsky, Y., Olia, A., Kwong, P.D.
Deposit date:2020-06-29
Release date:2020-08-12
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains
Biorxiv, 2020
6XM3
  • Download 6xm3
  • View 6xm3
Molmil generated image of 6xm3
STRUCTURE OF SARS-COV-2 SPIKE AT PH 5.5, SINGLE RBD UP, CONFORMATION 1
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Zhou, T., Tsybovsky, Y., Olia, A., Kwong, P.D.
Deposit date:2020-06-29
Release date:2020-08-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains
Biorxiv, 2020
6XM4
  • Download 6xm4
  • View 6xm4
Molmil generated image of 6xm4
STRUCTURE OF SARS-COV-2 SPIKE AT PH 5.5, SINGLE RBD UP, CONFORMATION 2
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Zhou, T., Tsybovsky, Y., Olia, A., Kwong, P.D.
Deposit date:2020-06-29
Release date:2020-08-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains
Biorxiv, 2020
6XM5
  • Download 6xm5
  • View 6xm5
Molmil generated image of 6xm5
STRUCTURE OF SARS-COV-2 SPIKE AT PH 5.5, ALL RBDS DOWN
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Zhou, T., Tsybovsky, Y., Olia, A., Kwong, P.D.
Deposit date:2020-06-29
Release date:2020-07-29
Last modified:2020-08-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains
Biorxiv, 2020
5K9J
  • Download 5k9j
  • View 5k9j
Molmil generated image of 5k9j
CRYSTAL STRUCTURE OF MULTIDONOR HV6-1-CLASS BROADLY NEUTRALIZING INFLUENZA A ANTIBODY 56.A.09 ISOLATED FOLLOWING H5 IMMUNIZATION.
Descriptor:56.a.09 heavy chain, 56.a.09 light chain, POLYETHYLENE GLYCOL (N=34)
Authors:Joyce, M.G., Thomas, P.V., Wheatley, A.K., McDermott, A.B., Mascola, J.R., Kwong, P.D.
Deposit date:2016-05-31
Release date:2016-07-27
Last modified:2016-08-10
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166, 2016
5K9K
  • Download 5k9k
  • View 5k9k
Molmil generated image of 5k9k
CRYSTAL STRUCTURE OF MULTIDONOR HV6-1-CLASS BROADLY NEUTRALIZING INFLUENZA A ANTIBODY 56.A.09 IN COMPLEX WITH HEMAGGLUTININ HONG KONG 1968.
Descriptor:56.a.09 Heavy chain, 56.a.09 Light chain, Hemagglutinin, ...
Authors:Joyce, M.G., Thomas, P.V., Wheatley, A.K., McDermott, A.B., Mascola, J.R., Kwong, P.D.
Deposit date:2016-05-31
Release date:2016-12-21
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166, 2016
5K9O
  • Download 5k9o
  • View 5k9o
Molmil generated image of 5k9o
CRYSTAL STRUCTURE OF MULTIDONOR HV1-18+HD3-9 CLASS BROADLY NEUTRALIZING INFLUENZA A ANTIBODY 31.B.09 IN COMPLEX WITH HEMAGGLUTININ H1 A/CALIFORNIA/04/2009
Descriptor:31.b.09 Heavy Fv, 31.b.09 Light Fv, Hemagglutinin, ...
Authors:Joyce, M.G., Thomas, P.V., Wheatley, A.K., McDermott, A.B., Mascola, J.R., Kwong, P.D.
Deposit date:2016-06-01
Release date:2016-12-28
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.387 Å)
Cite:Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166, 2016
5K9Q
  • Download 5k9q
  • View 5k9q
Molmil generated image of 5k9q
CRYSTAL STRUCTURE OF MULTIDONOR HV1-18-CLASS BROADLY NEUTRALIZING INFLUENZA A ANTIBODY 16.A.26 IN COMPLEX WITH A/HONG KONG/1-4-MA21-1/1968 (H3N2) HEMAGGLUTININ
Descriptor:Hemagglutinin HA1, Hemagglutinin HA2, 16.a.26 Heavy chain, ...
Authors:Joyce, M.G., Thomas, P.V., Wheatley, A.K., McDermott, A.B., Mascola, J.R., Kwong, P.D.
Deposit date:2016-06-01
Release date:2016-11-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.503 Å)
Cite:Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell(Cambridge,Mass.), 166, 2016
5KAN
  • Download 5kan
  • View 5kan
Molmil generated image of 5kan
CRYSTAL STRUCTURE OF MULTIDONOR HV1-18-CLASS BROADLY NEUTRALIZING INFLUENZA A ANTIBODY 16.G.07 IN COMPLEX WITH A/HONG KONG/1-4-MA21-1/1968 (H3N2) HEMAGGLUTININ
Descriptor:Hemagglutinin HA1, Hemagglutinin HA2, 16.g.07 Heavy chain, ...
Authors:Joyce, M.G., Thomas, P.V., Wheatley, A.K., McDermott, A.B., Mascola, J.R., Kwong, P.D.
Deposit date:2016-06-01
Release date:2016-11-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.785 Å)
Cite:Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell(Cambridge,Mass.), 166, 2016
<123>
167518
PDB entries from 2020-08-12