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7K43
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SARS-COV-2 SPIKE IN COMPLEX WITH THE S2M11 NEUTRALIZING ANTIBODY FAB FRAGMENT
Descriptor:SARS-CoV-2 spike glycoprotein, S2M11 Fab fragment (heavy chain), S2M11 Fab fragment (light chain), ...
Authors:Tortorici, M.A., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2020-09-14
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Science, 2020
7K45
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SARS-COV-2 SPIKE IN COMPLEX WITH THE S2E12 NEUTRALIZING ANTIBODY FAB FRAGMENT (LOCAL REFINEMENT OF THE RBD AND FAB VARIABLE DOMAINS)
Descriptor:S2E12 neutralizing antibody Fab fragment (heavy chain), S2E12 neutralizing antibody Fab fragment (light chain), Spike glycoprotein, ...
Authors:Tortorici, M.A., Veesler, D.
Deposit date:2020-09-14
Release date:2020-10-07
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms.
Science, 2020
4CBG
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PESTIVIRUS NS3 HELICASE
Descriptor:SERINE PROTEASE NS3, ACETATE ION
Authors:Tortorici, M.A., Duquerroy, S., Kwok, J., Vonrhein, C., Perez, J., Lamp, B., Bricogne, G., Rumenapf, T., Vachette, P., Rey, F.A.
Deposit date:2013-10-14
Release date:2015-01-21
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:X-Ray Structure of the Pestivirus Ns3 Helicase and its Conformation in Solution.
J.Virol., 89, 2015
4CBH
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PESTIVIRUS NS3 HELICASE
Descriptor:SERINE PROTEASE NS3
Authors:Tortorici, M.A., Duquerroy, S., Kwok, J., Vonrhein, C., Perez, J., Lamp, B., Bricogne, G., Rumenapf, T., Vachette, P., Rey, F.A.
Deposit date:2013-10-14
Release date:2015-01-21
Last modified:2018-06-20
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:X-Ray Structure of the Pestivirus Ns3 Helicase and its Conformation in Solution.
J.Virol., 89, 2015
4CBI
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PESTIVIRUS NS3 HELICASE
Descriptor:SERINE PROTEASE NS3
Authors:Tortorici, M.A., Duquerroy, S., Kwok, J., Vonrhein, C., Perez, J., Lamp, B., Bricogne, G., Rumenapf, T., Vachette, P., Rey, F.A.
Deposit date:2013-10-14
Release date:2015-01-21
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-Ray Structure of the Pestivirus Ns3 Helicase and its Conformation in Solution.
J.Virol., 89, 2015
4CBL
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PESTIVIRUS NS3 HELICASE
Descriptor:SERINE PROTEASE NS3
Authors:Tortorici, M.A., Duquerroy, S., Kwok, J., Vonrhein, C., Perez, J., Lamp, B., Bricogne, G., Rumenapf, T., Vachette, P., Rey, F.A.
Deposit date:2013-10-14
Release date:2015-01-21
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:X-Ray Structure of the Pestivirus Ns3 Helicase and its Conformation in Solution.
J.Virol., 89, 2015
4CBM
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PESTIVIRUS NS3 HELICASE
Descriptor:SERINE PROTEASE NS3
Authors:Tortorici, M.A., Duquerroy, S., Kwok, J., Vonrhein, C., Perez, J., Lamp, B., Bricogne, G., Rumenapf, T., Vachette, P., Rey, F.A.
Deposit date:2013-10-14
Release date:2015-01-21
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (3.27 Å)
Cite:X-Ray Structure of the Pestivirus Ns3 Helicase and its Conformation in Solution.
J.Virol., 89, 2015
5MZ4
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CRYSTAL STRUCTURE OF FULL-LENGH CSFV NS3/4A
Descriptor:Genome polyprotein,Genome polyprotein
Authors:Tortorici, M.A., Rey, F.A.
Deposit date:2017-01-30
Release date:2017-02-15
Method:X-RAY DIFFRACTION (3.048 Å)
Cite:A positive-strand RNA virus uses alternative protein-protein interactions within a viral protease/cofactor complex to switch between RNA replication and virion morphogenesis.
PLoS Pathog., 13, 2017
7JXE
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MAPPING NEUTRALIZING AND IMMUNODOMINANT SITES ON THE SARS-COV-2 SPIKE RECEPTOR-BINDING DOMAIN BY STRUCTURE-GUIDED HIGH-RESOLUTION SEROLOGY
Descriptor:S2X35 antigen-binding (Fab) fragment
Authors:Tortorici, M.A., Park, Y.J., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D.
Deposit date:2020-08-27
Release date:2020-10-14
Method:X-RAY DIFFRACTION (2.043 Å)
Cite:Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology.
Cell(Cambridge,Mass.), 2020
3JCL
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF A CORONAVIRUS SPIKE GLYCOPROTEIN TRIMER
Descriptor:Spike glycoprotein
Authors:Walls, A.C., Tortorici, M.A., Bosch, B.J., Frenz, B., Rottier, P.J.M., DiMaio, F., Rey, F.A., Veesler, D.
Deposit date:2015-12-21
Release date:2016-02-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer.
Nature, 531, 2016
4ADG
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CRYSTAL STRUCTURE OF THE RUBELLA VIRUS ENVELOPE GLYCOPROTEIN E1 IN POST-FUSION FORM (CRYSTAL FORM II)
Descriptor:E1 ENVELOPE GLYCOPROTEIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:DuBois, R.M., Vaney, M.C., Tortorici, M.A., Al Kurdi, R., Barba-Spaeth, G., Rey, F.A.
Deposit date:2011-12-26
Release date:2013-01-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1.
Nature, 493, 2013
4ADI
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CRYSTAL STRUCTURE OF THE RUBELLA VIRUS ENVELOPE GLYCOPROTEIN E1 IN POST-FUSION FORM (CRYSTAL FORM I)
Descriptor:E1 ENVELOPE GLYCOPROTEIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:DuBois, R.M., Vaney, M.C., Tortorici, M.A., Al Kurdi, R., Barba-Spaeth, G., Rey, F.A.
Deposit date:2011-12-26
Release date:2013-01-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1.
Nature, 493, 2013
4ADJ
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CRYSTAL STRUCTURE OF THE RUBELLA VIRUS GLYCOPROTEIN E1 IN ITS POST-FUSION FORM CRYSTALLIZED IN PRESENCE OF 1MM OF CALCIUM ACETATE
Descriptor:E1 ENVELOPE GLYCOPROTEIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:DuBois, R.M., Vaney, M.C., Tortorici, M.A., Al Kurdi, R., Barba-Spaeth, G., Rey, F.A.
Deposit date:2011-12-26
Release date:2013-01-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1.
Nature, 493, 2013
4B3V
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CRYSTAL STRUCTURE OF THE RUBELLA VIRUS GLYCOPROTEIN E1 IN ITS POST-FUSION FORM CRYSTALLIZED IN PRESENCE OF 20MM OF CALCIUM ACETATE
Descriptor:E1 ENVELOPE GLYCOPROTEIN, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-galactopyranose, ...
Authors:Vaney, M.C., DuBois, R.M., Tortorici, M.A., Rey, F.A.
Deposit date:2012-07-26
Release date:2013-01-09
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Functional and Evolutionary Insight from the Crystal Structure of Rubella Virus Protein E1.
Nature, 493, 2013
5SZS
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GLYCAN SHIELD AND EPITOPE MASKING OF A CORONAVIRUS SPIKE PROTEIN OBSERVED BY CRYO-ELECTRON MICROSCOPY
Descriptor:Spike glycoprotein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Walls, A.C., Tortorici, M.A., Frenz, B., Snijder, J., Li, W., Rey, F.A., DiMaio, F., Bosch, B.J., Veesler, D.
Deposit date:2016-08-15
Release date:2016-09-14
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Glycan shield and epitope masking of a coronavirus spike protein observed by cryo-electron microscopy.
Nat.Struct.Mol.Biol., 23, 2016
6B3O
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TECTONIC CONFORMATIONAL CHANGES OF A CORONAVIRUS SPIKE GLYCOPROTEIN PROMOTE MEMBRANE FUSION
Descriptor:Spike glycoprotein
Authors:Walls, A.C., Tortorici, M.A., Snijder, J., Xiong, X., Bosch, B.J., Rey, F.A., Veesler, D.
Deposit date:2017-09-22
Release date:2017-10-04
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6BFU
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GLYCAN SHIELD AND FUSION ACTIVATION OF A DELTACORONAVIRUS SPIKE GLYCOPROTEIN FINE-TUNED FOR ENTERIC INFECTIONS
Descriptor:Spike protein, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Xiong, X., Tortorici, M.A., Snijder, S., Yoshioka, C., Walls, A.C., Li, W., Seattle Structural Genomics Center for Infectious Disease (SSGCID), McGuire, A.T., Rey, F.A., Bosch, B.J., Veesler, D.
Deposit date:2017-10-27
Release date:2017-11-22
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Glycan Shield and Fusion Activation of a Deltacoronavirus Spike Glycoprotein Fine-Tuned for Enteric Infections.
J. Virol., 92, 2018
6NB3
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MERS-COV COMPLEX WITH HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, LCA60 light chain, LCA60 heavy chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB4
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MERS-COV S COMPLEX WITH HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, LCA60 heavy chain, LCA60 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB5
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CRYSTAL STRUCTURE OF ANTI- MERS-COV HUMAN NEUTRALIZING LCA60 ANTIBODY FAB FRAGMENT
Descriptor:LCA60 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB6
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SARS-COV COMPLEX WITH HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT (STATE 1)
Descriptor:Spike glycoprotein, S230 heavy chain, S230 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB7
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SARS-COV COMPLEX WITH HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT (STATE 2)
Descriptor:Spike glycoprotein, S230 heavy chain, S230 light chain, ...
Authors:Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6NB8
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CRYSTAL STRUCTURE OF ANTI- SARS-COV HUMAN NEUTRALIZING S230 ANTIBODY FAB FRAGMENT
Descriptor:S230 antigen-binding (Fab) fragment, heavy chain, light chain
Authors:Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2018-12-06
Release date:2019-02-06
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion.
Cell, 176, 2019
6Q04
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MERS-COV S STRUCTURE IN COMPLEX WITH 5-N-ACETYL NEURAMINIC ACID
Descriptor:Spike glycoprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Park, Y.J., Walls, A.C., Wang, Z., Sauer, M., Li, W., Tortorici, M.A., Bosch, B.J., DiMaio, F.D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-08-01
Release date:2019-12-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.
Nat.Struct.Mol.Biol., 26, 2019
6Q05
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MERS-COV S STRUCTURE IN COMPLEX WITH SIALYL-LEWISX
Descriptor:Spike glycoprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Park, Y.J., Walls, A.C., Wang, Z., Sauer, M., Li, W., Tortorici, M.A., Bosch, B.J., DiMaio, F.D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2019-08-01
Release date:2019-12-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structures of MERS-CoV spike glycoprotein in complex with sialoside attachment receptors.
Nat.Struct.Mol.Biol., 26, 2019
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170172
PDB entries from 2020-10-21