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3C22
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CRYSTAL STRUCTURE OF THE CARBOHYDRATE RECOGNITION DOMAIN OF HUMAN LANGERIN
Descriptor:C-type lectin domain family 4 member K, CALCIUM ION, MAGNESIUM ION
Authors:Thepaut, M.
Deposit date:2008-01-24
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural studies of langerin and Birbeck granule: a macromolecular organization model
Biochemistry, 48, 2009
1T6F
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CRYSTAL STRUCTURE OF THE COILED-COIL DIMERIZATION MOTIF OF GEMININ
Descriptor:Geminin
Authors:Thepaut, M., Maiorano, D., Guichou, J.-F., Auge, M.-T., Dumas, C., Mechali, M., Padilla, A.
Deposit date:2004-05-06
Release date:2004-07-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Crystal Structure of the Coiled-coil Dimerization Motif of Geminin: Structural and Functional Insights on DNA Replication Regulation
J.Mol.Biol., 342, 2004
1G33
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CRYSTAL STRUCTURE OF RAT PARVALBUMIN WITHOUT THE N-TERMINAL DOMAIN
Descriptor:PARVALBUMIN ALPHA, CALCIUM ION, SULFATE ION
Authors:Thepaut, M., Strub, M.P., Cave, A., Baneres, J.L., Berchtold, M.W., Dumas, C., Padilla, A.
Deposit date:2000-10-23
Release date:2001-10-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Structure of rat parvalbumin with deleted AB domain: implications for the evolution of EF hand calcium-binding proteins and possible physiological relevance.
Proteins, 45, 2001
2XR5
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE CARBOHYDRATE RECOGNITION DOMAIN OF HUMAN DC-SIGN WITH PSEUDO DIMANNOSIDE MIMIC.
Descriptor:CD209 ANTIGEN, ALPHA-D-MANNOSE, dimethyl (1S,2S,4S,5S)-4,5-dihydroxycyclohexane-1,2-dicarboxylate, ...
Authors:Thepaut, M., Suitkeviciute, I., Sattin, S., Reina, J., Bernardi, A., Fieschi, F.
Deposit date:2010-09-10
Release date:2011-10-19
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Structure of a Glycomimetic Ligand in the Carbohydrate Recognition Domain of C-Type Lectin Dc-Sign. Structural Requirements for Selectivity and Ligand Design.
J.Am.Chem.Soc., 135, 2013
2XR6
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CRYSTAL STRUCTURE OF THE COMPLEX OF THE CARBOHYDRATE RECOGNITION DOMAIN OF HUMAN DC-SIGN WITH PSEUDO TRIMANNOSIDE MIMIC.
Descriptor:CD209 ANTIGEN, ALPHA-D-MANNOSE, dimethyl (1S,2S,4S,5S)-4,5-dihydroxycyclohexane-1,2-dicarboxylate, ...
Authors:Thepaut, M., Suitkeviciute, I., Sattin, S., Reina, J., Bernardi, A., Fieschi, F.
Deposit date:2010-09-10
Release date:2011-10-19
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Unique Dc-Sign Clustering Activity of a Small Glycomimetic: A Lesson for Ligand Design.
Acs Chem.Biol., 9, 2014
6GHV
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STRUCTURE OF A DC-SIGN CRD IN COMPLEX WITH HIGH AFFINITY GLYCOMIMETIC.
Descriptor:CD209 antigen, [1-[(2~{S},3~{S},4~{R},5~{S},6~{R})-2-[(1~{S},2~{S},4~{S},5~{S})-2-(2-chloroethyloxy)-4,5-bis[[4-(hydroxymethyl)phenyl]methylcarbamoyl]cyclohexyl]oxy-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-3-yl]-1,2,3-triazol-4-yl]methylazanium, CALCIUM ION, ...
Authors:Thepaut, M., Achilli, S., Medve, L., Bernardi, A., Fieschi, F.
Deposit date:2018-05-09
Release date:2019-09-11
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Enhancing Potency and Selectivity of a DC-SIGN Glycomimetic Ligand by Fragment-Based Design: Structural Basis.
Chemistry, 25, 2019
5O89
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CRYSTAL STRUCTURE OF RSEGFP2 IN THE FLUORESCENT ON-STATE DETERMINED BY SFX
Descriptor:Green fluorescent protein
Authors:Coquelle, N., Sliwa, M., Woodhouse, J., Schiro, G., Adam, V., Aquila, A., Barends, T.R.M., Boutet, S., Byrdin, M., Carbajo, S., De la Mora, E., Doak, R.B., Feliks, M., Fieschi, F., Foucar, L., Guillon, V., Hilpert, M., Hunter, M., Jakobs, S., Koglin, J.E., Kovacsova, G., Lane, T.J., Levy, B., Liang, M., Nass, K., Ridard, J., Robinson, J.S., Roome, C.M., Ruckebusch, C., Seaberg, M., Thepaut, M., Cammarata, M., Demachy, I., Field, M., Shoeman, R.L., Bourgeois, D., Colletier, J.P., Schlichting, I., Weik, M.
Deposit date:2017-06-12
Release date:2017-12-13
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography.
Nat Chem, 10, 2018
5O8A
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CRYSTAL STRUCTURE OF RSEGFP2 IN THE NON-FLUORESCENT OFF-STATE DETERMINED BY SFX
Descriptor:Green fluorescent protein
Authors:Coquelle, N., Sliwa, M., Woodhouse, J., Schiro, G., Adam, V., Aquila, A., Barends, T.R.M., Boutet, S., Byrdin, M., Carbajo, S., De la Mora, E., Doak, R.B., Feliks, M., Fieschi, F., Foucar, L., Guillon, V., Hilpert, M., Hunter, M., Jakobs, S., Koglin, J.E., Kovacsova, G., Lane, T.J., Levy, B., Liang, M., Nass, K., Ridard, J., Robinson, J.S., Roome, C.M., Ruckebusch, C., Seaberg, M., Thepaut, M., Cammarata, M., Demachy, I., Field, M., Shoeman, R.L., Bourgeois, D., Colletier, J.P., Schlichting, I., Weik, M.
Deposit date:2017-06-12
Release date:2017-09-27
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography.
Nat Chem, 10, 2018
5O8B
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DIFFERENCE-REFINED EXCITED-STATE STRUCTURE OF RSEGFP2 1PS FOLLOWING 400NM-LASER IRRADIATION OF THE OFF-STATE.
Descriptor:Green fluorescent protein
Authors:Coquelle, N., Sliwa, M., Woodhouse, J., Schiro, G., Adam, V., Aquila, A., Barends, T.R.M., Boutet, S., Byrdin, M., Carbajo, S., De la Mora, E., Doak, R.B., Feliks, M., Fieschi, F., Foucar, L., Guillon, V., Hilpert, M., Hunter, M., Jakobs, S., Koglin, J.E., Kovacsova, G., Lane, T.J., Levy, B., Liang, M., Nass, K., Ridard, J., Robinson, J.S., Roome, C.M., Ruckebusch, C., Seaberg, M., Thepaut, M., Cammarata, M., Demachy, I., Field, M., Shoeman, R.L., Bourgeois, D., Colletier, J.P., Schlichting, I., Weik, M.
Deposit date:2017-06-12
Release date:2018-01-24
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography.
Nat Chem, 10, 2018
5O8C
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COMPOSITE STRUCTURE OF RSEGFP2 1PS FOLLOWING 400NM-LASER IRRADIATION OF THE OFF-STATE.
Descriptor:Green fluorescent protein
Authors:Coquelle, N., Sliwa, M., Woodhouse, J., Schiro, G., Adam, V., Aquila, A., Barends, T.R.M., Boutet, S., Byrdin, M., Carbajo, S., De la Mora, E., Doak, R.B., Feliks, M., Fieschi, F., Foucar, L., Guillon, V., Hilpert, M., Hunter, M., Jakobs, S., Koglin, J.E., Kovacsova, G., Lane, T.J., Levy, B., Liang, M., Nass, K., Ridard, J., Robinson, J.S., Roome, C.M., Ruckebusch, C., Seaberg, M., Thepaut, M., Cammarata, M., Demachy, I., Field, M., Shoeman, R.L., Bourgeois, D., Colletier, J.P., Schlichting, I., Weik, M.
Deposit date:2017-06-12
Release date:2017-12-06
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography.
Nat Chem, 10, 2018
4AK8
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STRUCTURE OF F241L MUTANT OF LANGERIN CARBOHYDRATE RECOGNITION DOMAIN.
Descriptor:C-TYPE LECTIN DOMAIN FAMILY 4 MEMBER K, CALCIUM ION, MAGNESIUM ION, ...
Authors:Chabrol, E., Thepaut, M., Dezutter-Dambuyant, C., Vives, C., Marcoux, J., Kahn, R., Valadeau-Guilemond, J., Vachette, P., Durand, D., Fieschi, F.
Deposit date:2012-02-22
Release date:2013-04-03
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Alteration of the Langerin Oligomerization State Affects Birbeck Granule Formation.
Biophys.J., 108, 2015
5G6U
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CRYSTAL STRUCTURE OF LANGERIN CARBOHYDRATE RECOGNITION DOMAIN WITH GLCNS6S
Descriptor:LANGERIN, TRYPTOPHAN, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, ...
Authors:Porkolab, V., Chabrol, E., Varga, N., Ordanini, S., Sutkeviciute, I., Thepaut, M., Bernardi, A., Fieschi, F.
Deposit date:2016-07-21
Release date:2018-02-21
Last modified:2018-03-28
Method:X-RAY DIFFRACTION (1.844 Å)
Cite:Rational-Differential Design of Highly Specific Glycomimetic Ligands: Targeting DC-SIGN and Excluding Langerin Recognition.
ACS Chem. Biol., 13, 2018