Author results

4P2G
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CRYSTAL STRUCTURE OF DJ-1 IN SULFINIC ACID FORM (AGED CRYSTAL)
Descriptor:Protein DJ-1, PENTAETHYLENE GLYCOL, 1,2-ETHANEDIOL
Authors:Tashiro, S., Wu, C.-X., Hoang, Q.Q., Caaveiro, J.M.M., Tsumoto, K.
Deposit date:2014-03-04
Release date:2014-04-09
Last modified:2014-07-23
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1.
Biochemistry, 53, 2014
4P34
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CRYSTAL STRUCTURE OF DJ-1 IN SULFENIC ACID FORM (FRESH CRYSTAL)
Descriptor:Protein DJ-1, PENTAETHYLENE GLYCOL
Authors:Tashiro, S., Wu, C.-X., Hoang, Q.Q., Caaveiro, J.M.M., Tsumoto, K.
Deposit date:2014-03-05
Release date:2014-04-09
Last modified:2015-09-23
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1.
Biochemistry, 53, 2014
4P35
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CRYSTAL STRUCTURE OF DJ-1 WITH ZINC(II) BOUND (CRYSTAL I)
Descriptor:Protein DJ-1, ZINC ION, CHLORIDE ION, ...
Authors:Tashiro, S., Wu, C.-X., Hoang, Q.Q., Caaveiro, J.M.M., Tsumoto, K.
Deposit date:2014-03-05
Release date:2014-04-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1.
Biochemistry, 53, 2014
4P36
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CRYSTAL STRUCTURE OF DJ-1 WITH ZN(II) BOUND (CRYSTAL 2)
Descriptor:Protein DJ-1, 2,5,8,11,14,17-HEXAOXANONADECAN-19-OL, ZINC ION
Authors:Tashiro, S., Wu, C.-X., Hoang, Q.Q., Caaveiro, J.M.M., Tsumoto, K.
Deposit date:2014-03-05
Release date:2014-04-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.182 Å)
Cite:Thermodynamic and Structural Characterization of the Specific Binding of Zn(II) to Human Protein DJ-1.
Biochemistry, 53, 2014
6AF5
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DJ-1 AFTER BACKSOAKING
Descriptor:Protein/nucleic acid deglycase DJ-1, ISATIN, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AF7
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DJ-1 C106S UNBOUND
Descriptor:Protein/nucleic acid deglycase DJ-1, PENTAETHYLENE GLYCOL, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AF9
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DJ-1 WITH ISATIN BOUND (HIGH CONCENTRATION)
Descriptor:Protein/nucleic acid deglycase DJ-1, ISATIN, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.39 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFA
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DJ-1 WITH ISATIN (LOW CONCENTRATION)
Descriptor:Protein/nucleic acid deglycase DJ-1, ISATIN, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFB
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DJ-1 C106S INCUBATED WITH ISATIN
Descriptor:Protein/nucleic acid deglycase DJ-1, ISATIN, CHLORIDE ION, ...
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFC
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DJ-1 WITH COMPOUND 4
Descriptor:Protein/nucleic acid deglycase DJ-1, 5-fluoranyl-1~{H}-indole-2,3-dione, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFD
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DJ-1 WITH COMPOUND 6
Descriptor:Protein/nucleic acid deglycase DJ-1, 7-methyl-1~{H}-indole-2,3-dione, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFE
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DJ-1 WITH COMPOUND 7
Descriptor:Protein/nucleic acid deglycase DJ-1, 7-(trifluoromethyl)-1~{H}-indole-2,3-dione, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFF
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DJ-1 WITH COMPOUND 8
Descriptor:Protein/nucleic acid deglycase DJ-1, methyl 2,3-bis(oxidanylidene)-1~{H}-indole-7-carboxylate, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFG
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DJ-1 WITH COMPOUND 9
Descriptor:Protein/nucleic acid deglycase DJ-1, 1-methylindole-2,3-dione
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFH
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DJ-1 WITH COMPOUND 10
Descriptor:Protein/nucleic acid deglycase DJ-1, 1-(2-phenylethyl)indole-2,3-dione, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFI
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DJ-1 WITH COMPOUND 11
Descriptor:Protein/nucleic acid deglycase DJ-1, 1-ethylindole-2,3-dione, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFJ
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DJ-1 WITH COMPOUND 13
Descriptor:Protein/nucleic acid deglycase DJ-1, butyl 2-[2,3-bis(oxidanylidene)indol-1-yl]ethanoate, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
6AFL
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DJ-1 WITH COMPOUND 15
Descriptor:Protein/nucleic acid deglycase DJ-1, 5-fluoranyl-1-(2-phenylethyl)indole-2,3-dione, CHLORIDE ION
Authors:Caaveiro, J.M.M., Tashiro, S., Tsumoto, K.
Deposit date:2018-08-08
Release date:2018-08-29
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Discovery and Optimization of Inhibitors of the Parkinson's Disease Associated Protein DJ-1.
ACS Chem. Biol., 13, 2018
5CI8
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CRYSTAL STRUCTURE OF HUMAN TOB IN COMPLEX WITH INHIBITOR FRAGMENT 1
Descriptor:Protein Tob1, pyrrolo[1,2-a]quinoxalin-4(5H)-one
Authors:Bai, Y., Tashiro, S., Nagatoishi, S., Suzuki, T., Tsumoto, K., Bartlam, M., Yamamoto, T.
Deposit date:2015-07-11
Release date:2015-11-18
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (2.328 Å)
Cite:Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach
Protein Cell, 6, 2015
5CI9
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CRYSTAL STRUCTURE OF HUMAN TOB IN COMPLEX WITH INHIBITOR FRAGMENT 6
Descriptor:Protein Tob1, 1-(propan-2-yl)-1H-benzimidazole-5-carboxylic acid, SODIUM ION
Authors:Bai, Y., Tashiro, S., Nagatoishi, S., Suzuki, T., Tsumoto, K., Bartlam, M., Yamamoto, T.
Deposit date:2015-07-11
Release date:2015-11-18
Last modified:2015-12-09
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for inhibition of the Tob-CNOT7 interaction by a fragment screening approach
Protein Cell, 6, 2015
3WWQ
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CRYSTAL STRUCTURE OF FAAP20 UBZ DOMAIN IN COMPLEX WITH LYS63-LINKED DIUBIQUITIN
Descriptor:Ubiquitin, Fanconi anemia-associated protein of 20 kDa, ZINC ION
Authors:Sato, Y., Fukai, S.
Deposit date:2014-06-23
Release date:2015-05-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Ubiquitin Recognition by Ubiquitin-Binding Zinc Finger of FAAP20
Plos One, 10, 2015
3VSY
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HIGH-RESOLUTION CRYSTAL STRUCTURE OF WILD-TYPE KSI IN THE APO FORM AT NEUTRAL PH
Descriptor:Steroid Delta-isomerase, SULFATE ION
Authors:Caaveiro, J.M.M., Kobe, A., Tsumoto, K.
Deposit date:2012-05-16
Release date:2013-02-27
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Incorporation of rapid thermodynamic data in fragment-based drug discovery.
J.Med.Chem., 56, 2013
4W4N
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CRYSTAL STRUCTURE OF HUMAN FC AT 1.80 A
Descriptor:Ig gamma-1 chain C region, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Caaveiro, J.M.M., Kiyoshi, M., Tsumoto, K.
Deposit date:2014-08-15
Release date:2015-04-29
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for binding of human IgG1 to its high-affinity human receptor Fc gamma RI
Nat Commun, 6, 2015
4W4O
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HIGH-RESOLUTION CRYSTAL STRUCTURE OF FC BOUND TO ITS HUMAN RECEPTOR FC-GAMMA-RI
Descriptor:Ig gamma-1 chain C region, High affinity immunoglobulin gamma Fc receptor I, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Caaveiro, J.M.M., Kiyoshi, M., Tsumoto, K.
Deposit date:2014-08-15
Release date:2015-04-29
Last modified:2015-05-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for binding of human IgG1 to its high-affinity human receptor Fc gamma RI
Nat Commun, 6, 2015
5Y0C
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CRYSTAL STRUCTURE OF THE HUMAN NUCLEOSOME AT 2.09 ANGSTROM RESOLUTION
Descriptor:DNA (146-MER), Histone H3.1, Histone H4, ...
Authors:Kurumizaka, H., Arimura, Y., Fujita, R., Noda, M.
Deposit date:2017-07-16
Release date:2018-07-18
Last modified:2018-11-21
Method:X-RAY DIFFRACTION (2.087 Å)
Cite:Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome.
Nucleic Acids Res., 46, 2018
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