2RSY | | SOLUTION STRUCTURE OF THE SH2 DOMAIN OF CSK IN COMPLEX WITH A PHOSPHOPEPTIDE FROM CBP | | Descriptor: | Tyrosine-protein kinase CSK, Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 | | Authors: | Tanaka, H., Akagi, K., Oneyama, C., Tanaka, M., Sasaki, Y., Kanou, T., Lee, Y., Yokogawa, D., Debenecker, M., Nakagawa, A., Okada, M., Ikegami, T. | | Deposit date: | 2012-09-10 | | Release date: | 2013-04-10 | | Last modified: | 2019-12-25 | | Method: | SOLUTION NMR | | Cite: | Identification of a new interaction mode between the Src homology 2 domain of C-terminal Src kinase (Csk) and Csk-binding protein/phosphoprotein associated with glycosphingolipid microdomains.
J.Biol.Chem., 288, 2013
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5WR7 | | CRYSTAL STRUCTURE OF TRK-A COMPLEXED WITH A SELECTIVE INHIBITOR CH7057288 | | Descriptor: | High affinity nerve growth factor receptor, N-tert-butyl-2-[2-[6,6-dimethyl-8-(methylsulfonylamino)-11-oxidanylidene-naphtho[2,3-b][1]benzofuran-3-yl]ethynyl]-6-methyl-pyridine-4-carboxamide | | Authors: | Tanaka, H., Blaesse, M., Augustin, M., Goesser, C. | | Deposit date: | 2016-11-30 | | Release date: | 2017-12-06 | | Last modified: | 2018-12-19 | | Method: | X-RAY DIFFRACTION (2.76 Å) | | Cite: | Selective TRK Inhibitor CH7057288 against TRK Fusion-Driven Cancer.
Mol. Cancer Ther., 17, 2018
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6KVD | | CRYSTAL STRUCTURE OF HUMAN NUCLEOSOME CONTAINING H2A.J | | Descriptor: | DNA (146-MER), Histone H3.1, Histone H4, ... | | Authors: | Tanaka, H., Koyama, M., Sato, S., Kujirai, T., Kurumizaka, H. | | Deposit date: | 2019-09-04 | | Release date: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2.21 Å) | | Cite: | Biochemical and structural analyses of the nucleosome containing human histone H2A.J.
J.Biochem., 2019
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1IOF | | X-RAY CRYSTALLINE STRUCTURES OF PYRROLIDONE CARBOXYL PEPTIDASE FROM A HYPERTHERMOPHILE, PYROCOCCUS FURIOSUS, AND ITS CYS-FREE MUTANT | | Descriptor: | PYRROLIDONE CARBOXYL PEPTIDASE | | Authors: | Tanaka, H., Chinami, M., Ota, M., Tsukihara, T., Yutani, K. | | Deposit date: | 2001-03-09 | | Release date: | 2001-03-21 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | X-ray crystalline structures of pyrrolidone carboxyl peptidase from a hyperthermophile, Pyrococcus furiosus, and its cys-free mutant.
J.Biochem., 130, 2001
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1IOI | | X-RAY CRYSTALLINE STRUCTURES OF PYRROLIDONE CARBOXYL PEPTIDASE FROM A HYPERTHERMOPHILE, PYROCOCCUS FURIOSUS, AND ITS CYS-FREE MUTANT | | Descriptor: | PYRROLIDONE CARBOXYL PEPTIDASE | | Authors: | Tanaka, H., Chinami, M., Ota, M., Tsukihara, T., Yutani, K. | | Deposit date: | 2001-03-09 | | Release date: | 2001-03-21 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | X-ray crystalline structures of pyrrolidone carboxyl peptidase from a hyperthermophile, Pyrococcus furiosus, and its cys-free mutant.
J.Biochem., 130, 2001
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3ANU | | CRYSTAL STRUCTURE OF D-SERINE DEHYDRATASE FROM CHICKEN KIDNEY | | Descriptor: | D-serine dehydratase, PYRIDOXAL-5'-PHOSPHATE, CHLORIDE ION, ... | | Authors: | Tanaka, H., Senda, M., Venugopalan, N., Yamamoto, A., Senda, T., Ishida, T., Horiike, K. | | Deposit date: | 2010-09-09 | | Release date: | 2011-06-15 | | Last modified: | 2013-08-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of a zinc-dependent D-serine dehydratase from chicken kidney
J.Biol.Chem., 286, 2011
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3ANV | | CRYSTAL STRUCTURE OF D-SERINE DEHYDRATASE FROM CHICKEN KIDNEY (2,3-DAP COMPLEX) | | Descriptor: | D-serine dehydratase, PYRIDOXAL-5'-PHOSPHATE, CHLORIDE ION, ... | | Authors: | Tanaka, H., Senda, M., Venugopalan, N., Yamamoto, A., Senda, T., Ishida, T., Horiike, K. | | Deposit date: | 2010-09-09 | | Release date: | 2011-06-15 | | Last modified: | 2014-05-14 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Crystal structure of a zinc-dependent D-serine dehydratase from chicken kidney
J.Biol.Chem., 286, 2011
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3ASI | | ALPHA-NEUREXIN-1 ECTODOMAIN FRAGMENT; LNS5-EGF3-LNS6 | | Descriptor: | Neurexin-1-alpha, CALCIUM ION, N-ACETYL-D-GLUCOSAMINE | | Authors: | Tanaka, H., Nogi, T., Yasui, N., Takagi, J. | | Deposit date: | 2010-12-13 | | Release date: | 2011-04-13 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural Basis for Variant-Specific Neuroligin-Binding by alpha-Neurexin
Plos One, 6, 2011
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3AWN | | CRYSTAL STRUCTURE OF D-SERINE DEHYDRATASE FROM CHICKEN KIDNEY (EDTA TREATED) | | Descriptor: | D-serine dehydratase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Tanaka, H., Senda, M., Venugopalan, N., Yamamoto, A., Senda, T., Ishida, T., Horiike, K. | | Deposit date: | 2011-03-25 | | Release date: | 2011-06-15 | | Last modified: | 2015-12-09 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal structure of a zinc-dependent D-serine dehydratase from chicken kidney.
J.Biol.Chem., 286, 2011
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3AWO | | CRYSTAL STRUCTURE OF D-SERINE DEHYDRATASE IN COMPLEX WITH D-SERINE FROM CHICKEN KIDNEY (EDTA-TREATED) | | Descriptor: | D-serine dehydratase, PYRIDOXAL-5'-PHOSPHATE, D-SERINE | | Authors: | Tanaka, H., Senda, M., Venugopalan, N., Yamamoto, A., Senda, T., Ishida, T., Horiike, K. | | Deposit date: | 2011-03-25 | | Release date: | 2011-06-15 | | Last modified: | 2015-12-09 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Crystal structure of a zinc-dependent D-serine dehydratase from chicken kidney.
J.Biol.Chem., 286, 2011
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3VKF | | CRYSTAL STRUCTURE OF NEUREXIN 1BETA/NEUROLIGIN 1 COMPLEX | | Descriptor: | Neuroligin-1, Neurexin-1-beta, N-ACETYL-D-GLUCOSAMINE, ... | | Authors: | Tanaka, H., Miyazaki, N., Nogi, T., Iwasaki, K., Takagi, J. | | Deposit date: | 2011-11-15 | | Release date: | 2012-08-01 | | Last modified: | 2013-06-26 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Higher-order architecture of cell adhesion mediated by polymorphic synaptic adhesion molecules neurexin and neuroligin.
Cell Rep, 2, 2012
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4V60 | | THE STRUCTURE OF RAT LIVER VAULT AT 3.5 ANGSTROM RESOLUTION | | Descriptor: | Major vault protein | | Authors: | Kato, K., Zhou, Y., Tanaka, H., Yao, M., Yamashita, E., Yoshimura, M., Tsukihara, T. | | Deposit date: | 2008-10-24 | | Release date: | 2014-07-09 | | Last modified: | 2014-12-10 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | The structure of rat liver vault at 3.5 angstrom resolution
Science, 323, 2009
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1A05 | | CRYSTAL STRUCTURE OF THE COMPLEX OF 3-ISOPROPYLMALATE DEHYDROGENASE FROM THIOBACILLUS FERROOXIDANS WITH 3-ISOPROPYLMALATE | | Descriptor: | 3-ISOPROPYLMALATE DEHYDROGENASE, MAGNESIUM ION, 3-ISOPROPYLMALIC ACID | | Authors: | Imada, K., Inagaki, K., Matsunami, H., Kawaguchi, H., Tanaka, H., Tanaka, N., Namba, K. | | Deposit date: | 1997-12-09 | | Release date: | 1998-06-17 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of 3-isopropylmalate dehydrogenase in complex with 3-isopropylmalate at 2.0 A resolution: the role of Glu88 in the unique substrate-recognition mechanism.
Structure, 6, 1998
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1GC0 | | CRYSTAL STRUCTURE OF THE PYRIDOXAL-5'-PHOSPHATE DEPENDENT L-METHIONINE GAMMA-LYASE FROM PSEUDOMONAS PUTIDA | | Descriptor: | METHIONINE GAMMA-LYASE | | Authors: | Motoshima, H., Inagaki, K., Kumasaka, T., Furuichi, M., Inoue, H., Tamura, T., Esaki, N., Soda, K., Tanaka, N., Yamamoto, M., Tanaka, H. | | Deposit date: | 2000-07-06 | | Release date: | 2002-05-08 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Crystal structure of the pyridoxal 5'-phosphate dependent L-methionine gamma-lyase from Pseudomonas putida.
J.Biochem., 128, 2000
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1GC2 | | CRYSTAL STRUCTURE OF THE PYRIDOXAL-5'-PHOSPHATE DEPENDENT L-METHIONINE GAMMA-LYASE FROM PSEUDOMONAS PUTIDA | | Descriptor: | METHIONINE GAMMA-LYASE | | Authors: | Motoshima, H., Inagaki, K., Kumasaka, T., Furuichi, M., Inoue, H., Tamura, T., Esaki, N., Soda, K., Tanaka, N., Yamamoto, M., Tanaka, H. | | Deposit date: | 2000-07-06 | | Release date: | 2002-05-08 | | Last modified: | 2019-11-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the pyridoxal 5'-phosphate dependent L-methionine gamma-lyase from Pseudomonas putida.
J.Biochem., 128, 2000
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2E1X | | NMR STRUCTURE OF THE HIV-2 NUCLEOCAPSID PROTEIN | | Descriptor: | Gag-Pol polyprotein (Pr160Gag-Pol), ZINC ION | | Authors: | Matsui, T., Kodera, Y., Miyauchi, E., Tanaka, H., Endoh, H., Komatsu, H., Tanaka, T., Kohno, T., Maeda, T. | | Deposit date: | 2006-11-03 | | Release date: | 2007-06-05 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | Structural role of the secondary active domain of HIV-2 NCp8 in multi-functionality
Biochem.Biophys.Res.Commun., 358, 2007
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2EC7 | | SOLUTION STRUCTURE OF HUMAN IMMUNODIFICIENCY VIRUS TYPE-2 NUCLEOCAPSID PROTEIN | | Descriptor: | Gag polyprotein (Pr55Gag), ZINC ION | | Authors: | Matsui, T., Kodera, Y., Tanaka, T., Endoh, H., Tanaka, H., Miyauchi, E., Komatsu, H., Kohno, T., Maeda, T. | | Deposit date: | 2007-02-10 | | Release date: | 2008-02-19 | | Last modified: | 2019-12-11 | | Method: | SOLUTION NMR | | Cite: | The RNA recognition mechanism of human immunodeficiency virus (HIV) type 2 NCp8 is different from that of HIV-1 NCp7
Biochemistry, 48, 2009
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4Y04 | | CRYSTAL STRUCTURE OF DIPEPTIDYL PEPTIDASE 11 (DPP11) FROM PORPHYROMONAS GINGIVALIS (SPACE) | | Descriptor: | Peptidase S46, POTASSIUM ION, GLYCEROL | | Authors: | Sakamoto, Y., Suzuki, Y., Iizuka, I., Tateoka, C., Roppongi, S., Fujimoto, M., Inaka, K., Tanaka, H., Yamada, M., Ohta, K., Nonaka, T., Ogasawara, W., Tanaka, N. | | Deposit date: | 2015-02-05 | | Release date: | 2015-07-15 | | Method: | X-RAY DIFFRACTION (1.66 Å) | | Cite: | Structural and mutational analyses of dipeptidyl peptidase 11 from Porphyromonas gingivalis reveal the molecular basis for strict substrate specificity.
Sci Rep, 5, 2015
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3KLR | | BOVINE H-PROTEIN AT 0.88 ANGSTROM RESOLUTION | | Descriptor: | Glycine cleavage system H protein, SULFATE ION, GLYCEROL | | Authors: | Higashiura, A., Kurakane, T., Matsuda, M., Suzuki, M., Inaka, K., Sato, M., Tanaka, H., Fujiwara, K., Nakagawa, A. | | Deposit date: | 2009-11-09 | | Release date: | 2010-06-09 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (0.88 Å) | | Cite: | High-resolution X-ray crystal structure of bovine H-protein at 0.88 A resolution
Acta Crystallogr.,Sect.D, 66, 2010
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3X2L | | X-RAY STRUCTURE OF PCCEL45A APO FORM AT 95K. | | Descriptor: | Endoglucanase V-like protein, 3-methylpentane-1,5-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | | Authors: | Nakamura, A., Ishida, T., Ohta, K., Tanaka, H., Inaka, K., Samejima, M., Igarashi, K. | | Deposit date: | 2014-12-22 | | Release date: | 2015-10-14 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (0.83 Å) | | Cite: | "Newton's cradle" proton relay with amide-imidic acid tautomerization in inverting cellulase visualized by neutron crystallography.
Sci Adv, 1, 2015
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1C1B | | CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH GCA-186 | | Descriptor: | HIV-1 REVERSE TRANSCRIPTASE (A-CHAIN), HIV-1 REVERSE TRANSCRIPTASE (B-CHAIN), 6-(3',5'-DIMETHYLBENZYL)-1-ETHOXYMETHYL-5-ISOPROPYLURACIL | | Authors: | Hopkins, A.L., Ren, J., Tanaka, H., Baba, B., Okamato, M., Stuart, D.I., Stammers, D.K. | | Deposit date: | 1999-07-21 | | Release date: | 2000-07-21 | | Last modified: | 2014-11-12 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants.
J.Med.Chem., 42, 1999
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1C1C | | CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH TNK-6123 | | Descriptor: | HIV-1 REVERSE TRANSCRIPTASE (A-CHAIN), HIV-1 REVERSE TRANSCRIPTASE (B-CHAIN), 6-(cyclohexylsulfanyl)-1-(ethoxymethyl)-5-(1-methylethyl)pyrimidine-2,4(1H,3H)-dione | | Authors: | Hopkins, A.L., Ren, J., Tanaka, H., Baba, M., Okamato, M., Stuart, D.I., Stammers, D.K. | | Deposit date: | 1999-07-21 | | Release date: | 2000-07-21 | | Last modified: | 2014-11-12 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Design of MKC-442 (emivirine) analogues with improved activity against drug-resistant HIV mutants.
J.Med.Chem., 42, 1999
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1V66 | | SOLUTION STRUCTURE OF HUMAN P53 BINDING DOMAIN OF PIAS-1 | | Descriptor: | Protein inhibitor of activated STAT protein 1 | | Authors: | Okubo, S., Hara, F., Tsuchida, Y., Shimotakahara, S., Suzuki, S., Hatanaka, H., Yokoyama, S., Tanaka, H., Yasuda, H., Shindo, H., RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2003-11-27 | | Release date: | 2004-12-07 | | Last modified: | 2011-07-13 | | Method: | SOLUTION NMR | | Cite: | NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomers
J.Biol.Chem., 279, 2004
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4HL8 | | RE-REFINEMENT OF THE VAULT RIBONUCLEOPROTEIN PARTICLE | | Descriptor: | Major vault protein | | Authors: | Casanas, A., Querol-Audi, J., Guerra, P., Pous, J., Tanaka, H., Tsukihara, T., Verdaguer, V., Fita, I. | | Deposit date: | 2012-10-16 | | Release date: | 2013-06-05 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | New features of vault architecture and dynamics revealed by novel refinement using the deformable elastic network approach.
Acta Crystallogr.,Sect.D, 69, 2013
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1WUA | | THE STRUCTURE OF APLYRONINE A-ACTIN COMPLEX | | Descriptor: | Actin, alpha skeletal muscle, CALCIUM ION, ... | | Authors: | Hirata, K., Muraoka, S., Suenaga, K., Kuroda, T., Kato, K., Tanaka, H., Yamamoto, M., Takata, M., Yamada, K., Kigoshi, H. | | Deposit date: | 2004-12-03 | | Release date: | 2006-02-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Structure basis for antitumor effect of aplyronine a
J.Mol.Biol., 356, 2006
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