1Q1O
| Solution Structure of the PB1 Domain of Cdc24p (Long Form) | Descriptor: | Cell division control protein 24 | Authors: | Yoshinaga, S, Kohjima, M, Ogura, K, Yokochi, M, Takeya, R, Ito, T, Sumimoto, H, Inagaki, F. | Deposit date: | 2003-07-22 | Release date: | 2003-10-14 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The PB1 domain and the PC motif-containing region are structurally similar protein binding modules EMBO J., 22, 2003
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1K4U
| Solution structure of the C-terminal SH3 domain of p67phox complexed with the C-terminal tail region of p47phox | Descriptor: | PHAGOCYTE NADPH OXIDASE SUBUNIT P47PHOX, PHAGOCYTE NADPH OXIDASE SUBUNIT P67PHOX | Authors: | Kami, K, Takeya, R, Sumimoto, H, Kohda, D. | Deposit date: | 2001-10-08 | Release date: | 2002-04-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p. EMBO J., 21, 2002
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1WMH
| Crystal structure of a PB1 domain complex of Protein kinase c iota and Par6 alpha | Descriptor: | Partitioning defective-6 homolog alpha, Protein kinase C, iota type | Authors: | Hirano, Y, Yoshinaga, S, Suzuki, N.N, Horiuchi, M, Kohjima, M, Takeya, R, Sumimoto, H, Inagaki, F. | Deposit date: | 2004-07-09 | Release date: | 2004-12-07 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of a Cell Polarity Regulator, a Complex between Atypical PKC and Par6 PB1 Domains J.Biol.Chem., 280, 2005
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2DYB
| The crystal structure of human p40(phox) | Descriptor: | Neutrophil cytosol factor 4 | Authors: | Honbou, K. | Deposit date: | 2006-09-08 | Release date: | 2007-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.15 Å) | Cite: | Full-length p40phox structure suggests a basis for regulation mechanism of its membrane binding. Embo J., 26, 2007
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1WLP
| Solution Structure Of The P22Phox-P47Phox Complex | Descriptor: | Cytochrome b-245 light chain, Neutrophil cytosol factor 1 | Authors: | Ogura, K, Torikai, S, Saikawa, K, Yuzawa, S, Sumimoto, H, Inagaki, F. | Deposit date: | 2004-06-29 | Release date: | 2005-10-04 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR solution structure of the tandem Src homology 3 domains of p47phox complexed with a p22phox-derived proline-rich peptide J.Biol.Chem., 281, 2006
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7YV1
| Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor LUNA18 and KA30L Fab | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, KA30L Fab H-chain, ... | Authors: | Irie, M, Fukami, T.A, Matsuo, A, Saka, K, Nishimura, M, Saito, H, Torizawa, T, Tanada, M, Ohta, A. | Deposit date: | 2022-08-18 | Release date: | 2023-07-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.454 Å) | Cite: | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets. J.Am.Chem.Soc., 145, 2023
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7YUZ
| Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP8784 | Descriptor: | AP8784, GUANOSINE-5'-DIPHOSPHATE, IODIDE ION, ... | Authors: | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | Deposit date: | 2022-08-18 | Release date: | 2023-07-26 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.878 Å) | Cite: | Validation of a New Methodology to Create Oral Drugs beyond the Rule of 5 for Intracellular Tough Targets. J.Am.Chem.Soc., 145, 2023
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8JJS
| Human K-Ras G12D (GDP-bound) in complex with cyclic peptide inhibitor AP10343 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Isoform 2B of GTPase KRas, MAA-ILE-SAR-SAR-7T2-SAR-IAE-LEU-MEA-MLE-7TK, ... | Authors: | Irie, M, Fukami, T.A, Tanada, M, Ohta, A, Torizawa, T. | Deposit date: | 2023-05-31 | Release date: | 2023-07-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.534 Å) | Cite: | Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor. J.Am.Chem.Soc., 145, 2023
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