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3MGO
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CRYSTAL STRUCTURE OF A H5-SPECIFIC CTL EPITOPE DERIVED FROM H5N1 INFLUENZA VIRUS IN COMPLEX WITH HLA-A*0201
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Sun, Y., Liu, J., Yang, M., Gao, F., Zhou, J., Kitamura, Y.
Deposit date:2010-04-07
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Identification and structural definition of H5-specific CTL epitopes restricted by HLA-A*0201 derived from the H5N1 subtype of influenza A viruses
J.Gen.Virol., 91, 2010
3MGT
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CRYSTAL STRUCTURE OF A H5-SPECIFIC CTL EPITOPE VARIANT DERIVED FROM H5N1 INFLUENZA VIRUS IN COMPLEX WITH HLA-A*0201
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Sun, Y., Liu, J., Yang, M., Gao, F., Zhou, J., Kitamura, Y.
Deposit date:2010-04-07
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:Identification and structural definition of H5-specific CTL epitopes restricted by HLA-A*0201 derived from the H5N1 subtype of influenza A viruses
J.Gen.Virol., 91, 2010
6BLY
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CRYO-EM STRUCTURE OF HUMAN CPSF-160-WDR33 COMPLEX AT 3.36A RESOLUTION
Descriptor:Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33
Authors:Sun, Y., Zhang, Y., Hamilton, K., Walz, T., Tong, L.
Deposit date:2017-11-12
Release date:2017-11-22
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6BM0
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CRYO-EM STRUCTURE OF HUMAN CPSF-160-WDR33 COMPLEX AT 3.8 A RESOLUTION
Descriptor:Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33
Authors:Sun, Y., Zhang, Y., Hamilton, K., Walz, T., Tong, L.
Deposit date:2017-11-12
Release date:2017-11-22
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DNH
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CRYO-EM STRUCTURE OF HUMAN CPSF-160-WDR33-CPSF-30-PAS RNA COMPLEX AT 3.4 A RESOLUTION
Descriptor:Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33, Cleavage and polyadenylation specificity factor subunit 4, ...
Authors:Sun, Y., Zhang, Y., Hamilton, K., Walz, T., Tong, L.
Deposit date:2018-06-06
Release date:2018-06-27
Last modified:2020-01-01
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular basis for the recognition of the human AAUAAA polyadenylation signal.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3IFU
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THE CRYSTAL STRUCTURE OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS (PRRSV) LEADER PROTEASE NSP1
Descriptor:Non-structural protein, ZINC ION
Authors:Sun, Y., Xue, F., Guo, Y., Ma, M., Lou, Z., Rao, Z.
Deposit date:2009-07-26
Release date:2009-10-27
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.42 Å)
Cite:Crystal structure of porcine reproductive and respiratory syndrome virus leader protease Nsp1alpha
J.Virol., 83, 2009
4I42
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E.COLI. 1,4-DIHYDROXY-2-NAPHTHOYL COENZYME A SYNTHASE (ECMENB) IN COMPLEX WITH 1-HYDROXY-2-NAPHTHOYL-COA
Descriptor:1,4-Dihydroxy-2-naphthoyl-CoA synthase, 1-hydroxy-2-naphthoyl-CoA, 1,2-ETHANEDIOL, ...
Authors:Sun, Y., Song, H., Li, J., Li, Y., Jiang, M., Zhou, J., Guo, Z.
Deposit date:2012-11-27
Release date:2013-05-08
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (1.848 Å)
Cite:Structural basis of the induced-fit mechanism of 1,4-dihydroxy-2-naphthoyl coenzyme A synthase from the crotonase fold superfamily
Plos One, 8, 2013
4MXD
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1.45 ANGSTRONM CRYSTAL STRUCTURE OF E.COLI 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE (MENH)
Descriptor:2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, SULFATE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Sun, Y., Yin, S., Feng, Y., Li, J., Zhou, J., Liu, C., Zhu, G., Guo, Z.
Deposit date:2013-09-26
Release date:2014-04-23
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Molecular Basis of the General Base Catalysis of an alpha/beta-Hydrolase Catalytic Triad
J.Biol.Chem., 2014
4MYD
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1.37 ANGSTROM CRYSTAL STRUCTURE OF E. COLI 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE (MENH) IN COMPLEX WITH SHCHC
Descriptor:2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID
Authors:Sun, Y., Yin, S., Feng, Y., Li, J., Zhou, J., Liu, C., Zhu, G., Guo, Z.
Deposit date:2013-09-27
Release date:2014-04-23
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (1.374 Å)
Cite:Molecular Basis of the General Base Catalysis of an alpha/beta-Hydrolase Catalytic Triad
J.Biol.Chem., 2014
4MYS
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1.4 ANGSTROM CRYSTAL STRUCTURE OF 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE WITH SHCHC AND PYRUVATE
Descriptor:2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, 2-(3-CARBOXYPROPIONYL)-6-HYDROXY-CYCLOHEXA-2,4-DIENE CARBOXYLIC ACID, GLYCEROL, ...
Authors:Sun, Y., Yin, S., Feng, Y., Li, J., Zhou, J., Liu, C., Zhu, G., Guo, Z.
Deposit date:2013-09-28
Release date:2014-04-23
Last modified:2014-05-07
Method:X-RAY DIFFRACTION (1.423 Å)
Cite:Molecular Basis of the General Base Catalysis of an alpha/beta-Hydrolase Catalytic Triad
J.Biol.Chem., 2014
6V4X
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CRYO-EM STRUCTURE OF AN ACTIVE HUMAN HISTONE PRE-MRNA 3'-END PROCESSING MACHINERY AT 3.2 ANGSTROM RESOLUTION
Descriptor:Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein-associated proteins B and B', Small nuclear ribonucleoprotein F, ...
Authors:Sun, Y., Zhang, Y., Walz, T., Tong, L.
Deposit date:2019-12-02
Release date:2020-02-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of an active human histone pre-mRNA 3'-end processing machinery.
Science, 367, 2020
6PPO
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RHINOVIRUS C15 COMPLEXED WITH DOMAIN I OF RECEPTOR CDHR3
Descriptor:Capsid protein VP1, Capsid protein VP3, Capsid protein VP2, ...
Authors:Sun, Y., Watters, K., Klose, T., Palmenberg, A.C.
Deposit date:2019-07-08
Release date:2020-03-11
Last modified:2020-04-15
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of rhinovirus C15a bound to its cadherin-related protein 3 receptor.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PSF
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RHINOVIRUS C15 COMPLEXED WITH DOMAINS I AND II OF RECEPTOR CDHR3
Descriptor:Capsid protein VP1, Capsid protein VP3, Capsid protein VP2, ...
Authors:Sun, Y., Watters, K., Klose, T., Palmenberg, A.C.
Deposit date:2019-07-12
Release date:2020-03-11
Last modified:2020-04-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structure of rhinovirus C15a bound to its cadherin-related protein 3 receptor.
Proc.Natl.Acad.Sci.USA, 117, 2020
1GP8
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NMR SOLUTION STRUCTURE OF THE COAT PROTEIN-BINDING DOMAIN OF BACTERIOPHAGE P22 SCAFFOLDING PROTEIN
Descriptor:PROTEIN (SCAFFOLDING PROTEIN)
Authors:Sun, Y., Parker, M.H., Weigele, P., Casjens, S., Prevelige Jr., P.E., Krishna, N.R.
Deposit date:1999-05-11
Release date:1999-05-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the coat protein-binding domain of the scaffolding protein from a double-stranded DNA virus.
J.Mol.Biol., 297, 2000
1LB8
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CRYSTAL STRUCTURE OF THE NON-DESENSITIZING GLUR2 LIGAND BINDING CORE MUTANT (S1S2J-L483Y) IN COMPLEX WITH AMPA AT 2.3 RESOLUTION
Descriptor:Glutamate receptor 2, (S)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID
Authors:Sun, Y., Olson, R., Horning, M., Armstrong, N., Mayer, M., Gouaux, E.
Deposit date:2002-04-02
Release date:2002-06-05
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
1LB9
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CRYSTAL STRUCTURE OF THE NON-DESENSITIZING GLUR2 LIGAND BINDING CORE MUTANT (S1S2J-L483Y) IN COMPLEX WITH ANTAGONIST DNQX AT 2.3 A RESOLUTION
Descriptor:Glutamate receptor 2, 6,7-DINITROQUINOXALINE-2,3-DIONE, SULFATE ION
Authors:Sun, Y., Olson, R., Horning, M., Armstrong, N., Mayer, M., Gouaux, E.
Deposit date:2002-04-02
Release date:2002-06-05
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
1LBB
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CRYSTAL STRUCTURE OF THE GLUR2 LIGAND BINDING DOMAIN MUTANT (S1S2J-N754D) IN COMPLEX WITH KAINATE AT 2.1 A RESOLUTION
Descriptor:Glutamine receptor 2, 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE
Authors:Sun, Y., Olson, R., Horning, M., Armstrong, N., Mayer, M., Gouaux, E.
Deposit date:2002-04-02
Release date:2002-06-05
Last modified:2017-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
1LBC
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CRYSTAL STRUCTURE OF GLUR2 LIGAND BINDING CORE (S1S2J-N775S) IN COMPLEX WITH CYCLOTHIAZIDE (CTZ) AS WELL AS GLUTAMATE AT 1.8 A RESOLUTION
Descriptor:Glutamine Receptor 2, ZINC ION, GLUTAMIC ACID, ...
Authors:Sun, Y., Olson, R., Horning, M., Armstrong, N., Mayer, M., Gouaux, E.
Deposit date:2002-04-02
Release date:2002-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mechanism of glutamate receptor desensitization.
Nature, 417, 2002
2GP8
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NMR SOLUTION STRUCTURE OF THE COAT PROTEIN-BINDING DOMAIN OF BACTERIOPHAGE P22 SCAFFOLDING PROTEIN
Descriptor:PROTEIN (SCAFFOLDING PROTEIN)
Authors:Sun, Y., Parker, M.H., Weigele, P., Casjens, S., Prevelige Jr., P.E., Krishna, N.R.
Deposit date:1999-05-11
Release date:1999-05-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the coat protein-binding domain of the scaffolding protein from a double-stranded DNA virus.
J.Mol.Biol., 297, 2000
2N1I
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STRUCTURE OF THE PR DOMAIN FROM PRDM16
Descriptor:PR domain zinc finger protein 16
Authors:Sun, Y., Armstrong, G., Briknarova, K.
Deposit date:2015-04-02
Release date:2016-07-06
Method:SOLUTION NMR
Cite:Structure of the PR Domain from PRDM16
To be Published
2Q5X
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF HNUP98
Descriptor:Nuclear pore complex protein Nup98
Authors:Sun, Y., Guo, H.C.
Deposit date:2007-06-03
Release date:2008-10-14
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural constraints on autoprocessing of the human nucleoporin Nup98.
Protein Sci., 17, 2008
2Q5Y
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF HNUP98
Descriptor:Nuclear pore complex protein Nup98, Nuclear pore complex protein Nup96
Authors:Sun, Y., Guo, H.C.
Deposit date:2007-06-03
Release date:2008-10-14
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural constraints on autoprocessing of the human nucleoporin Nup98.
Protein Sci., 17, 2008
4MG3
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CRYSTAL STRUCTURAL ANALYSIS OF 2A PROTEASE FROM COXSACKIEVIRUS A16
Descriptor:Protease 2A, ZINC ION, PENTAETHYLENE GLYCOL, ...
Authors:Sun, Y., Wang, X., Dang, M., Yuan, S.
Deposit date:2013-08-28
Release date:2014-03-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:An open conformation determined by a structural switch for 2A protease from coxsackievirus A16.
Protein Cell, 4, 2013
6O5K
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MURINE TRIM28 BBOX1 DOMAIN
Descriptor:Transcription intermediary factor 1-beta, ZINC ION
Authors:Sun, Y., Keown, J.R., Goldstone, D.C.
Deposit date:2019-03-03
Release date:2019-06-19
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family.
J.Mol.Biol., 431, 2019
6URG
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CRYO-EM STRUCTURE OF HUMAN CPSF160-WDR33-CPSF30-CPSF100 PIM COMPLEX
Descriptor:Cleavage and polyadenylation specificity factor subunit 1, pre-mRNA 3' end processing protein WDR33, Cleavage and polyadenylation specificity factor subunit 4, ...
Authors:Sun, Y., Zhang, Y., Walz, T., Tong, L.
Deposit date:2019-10-23
Release date:2019-11-27
Last modified:2020-03-04
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural Insights into the Human Pre-mRNA 3'-End Processing Machinery.
Mol.Cell, 77, 2020