Author results

5IIW
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CORKSCREW ASSEMBLY OF SOD1 RESIDUES 28-38 WITHOUT POTASSIUM IODIDE
Descriptor:Superoxide dismutase [Cu-Zn]
Authors:Sangwan, S., Zhao, A., Sawaya, M.R., Eisenberg, D.
Deposit date:2016-03-01
Release date:2017-06-28
Last modified:2019-01-09
Method:X-RAY DIFFRACTION (2 Å)
Cite:Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS).
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5E5V
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STRUCTURE OF AMYLOID FORMING PEPTIDE NFGAILS (RESIDUES 22-28) FROM ISLET AMYLOID POLYPEPTIDE
Descriptor:NFGAILS (22-28) from islet amyloid polypeptide, synthesized
Authors:Soriaga, A.B., Macdonald, R., Sawaya, M.R., Sangwan, S., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E5X
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE ANFLVH (RESIDUES 13-18) FROM ISLET AMYLOID POLYPEPTIDE
Descriptor:ANFLVH (residues 13-18) from islet amyloid polypeptide
Authors:Soriaga, A.B., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E5Z
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE LVHSSN (RESIDUES
Descriptor:LVHSSN (residues 16-21) from islet amyloid polypeptide
Authors:Soriaga, A.B., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.664 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5E61
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STRUCTURE OF AMYLOID-FORMING PEPTIDE FGAILSS (RESIDUES 23-29) FROM ISLET AMYLOID POLYPEPTIDE
Descriptor:FGAILSS (residues 23-29) from islet amyloid polypeptide
Authors:Soriaga, A.B., Eisenberg, D.
Deposit date:2015-10-09
Release date:2015-12-16
Last modified:2016-07-20
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets.
J.Phys.Chem.B, 120, 2016
5DLI
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CORKSCREW ASSEMBLY OF SOD1 RESIDUES 28-38
Descriptor:Superoxide dismutase [Cu-Zn], GLYCEROL, IODIDE ION
Authors:Sangwan, S., Zhao, A., Sawaya, M.R., Eisenberg, D.
Deposit date:2015-09-05
Release date:2016-09-14
Last modified:2019-01-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS).
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4RP6
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STRUCTURE OF THE AMYLOID-FORMING SEGMENT LTIITLE FROM P53 (RESIDUES 252-258)
Descriptor:LTIITLE heptapeptide segment from p53
Authors:Soriaga, A.B., Soragni, A., Eisenberg, D.
Deposit date:2014-10-29
Release date:2016-01-13
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Cancer Cell, 29, 2016
4RP7
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STRUCTURE OF THE AMYLOID-FORMING SEGMENT TIITLE FROM P53 (RESIDUES 253-258)
Descriptor:TIITLE hexapeptide segment from p53, ZINC ION
Authors:Soriaga, A.B., Soragni, A., Eisenberg, D.
Deposit date:2014-10-29
Release date:2016-01-13
Last modified:2016-01-27
Method:X-RAY DIFFRACTION (1.576 Å)
Cite:A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas.
Cancer Cell, 29, 2016
4QXX
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STRUCTURE OF THE AMYLOID FORMING PEPTIDE GNLVS (RESIDUES 26-30) FROM THE EOSINOPHIL MAJOR BASIC PROTEIN (EMBP)
Descriptor:Bone marrow proteoglycan
Authors:Soriaga, A.B., Soragni, A., Sawaya, M.R., Eisenberg, D.
Deposit date:2014-07-22
Release date:2015-03-18
Last modified:2015-04-08
Method:X-RAY DIFFRACTION (1.445 Å)
Cite:Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation.
Mol.Cell, 57, 2015
4NP8
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STRUCTURE OF AN AMYLOID FORMING PEPTIDE VQIVYK FROM THE SECOND REPEAT REGION OF TAU (ALTERNATE POLYMORPH)
Descriptor:Microtubule-associated protein tau
Authors:Landau, M., Eisenberg, D., Sawaya, M.R., Dannenberg, J., Kobko, N.
Deposit date:2013-11-20
Release date:2013-12-18
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Molecular mechanisms for protein-encoded inheritance.
Nat.Struct.Mol.Biol., 16, 2009
3SGM
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BROMODERIVATIVE-2 OF AMYLOID-RELATED SEGMENT OF ALPHAB-CRYSTALLIN RESIDUES 90-100
Descriptor:Alpha-crystallin B chain, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Laganowsky, A., Sawaya, M.R., Cascio, D., Eisenberg, D.
Deposit date:2011-06-15
Release date:2012-03-21
Method:X-RAY DIFFRACTION (1.7006 Å)
Cite:Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
3SGN
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BROMODERIVATIVE-8 OF AMYLOID-RELATED SEGMENT OF ALPHAB-CRYSTALLIN RESIDUES 90-100
Descriptor:Alpha-crystallin B chain
Authors:Laganowsky, A., Sawaya, M.R., Cascio, D., Eisenberg, D.
Deposit date:2011-06-15
Release date:2012-03-21
Method:X-RAY DIFFRACTION (2.807 Å)
Cite:Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
3SGO
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AMYLOID-RELATED SEGMENT OF ALPHAB-CRYSTALLIN RESIDUES 90-100
Descriptor:Alpha-crystallin B chain
Authors:Laganowsky, A., Sawaya, M.R., Cascio, D., Eisenberg, D.
Deposit date:2011-06-15
Release date:2012-03-21
Method:X-RAY DIFFRACTION (2.557 Å)
Cite:Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
3SGP
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AMYLOID-RELATED SEGMENT OF ALPHAB-CRYSTALLIN RESIDUES 90-100 MUTANT V91L
Descriptor:Alpha-crystallin B chain, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Laganowsky, A., Sawaya, M.R., Cascio, D., Eisenberg, D.
Deposit date:2011-06-15
Release date:2012-03-21
Method:X-RAY DIFFRACTION (1.4016 Å)
Cite:Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
3SGR
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TANDEM REPEAT OF AMYLOID-RELATED SEGMENT OF ALPHAB-CRYSTALLIN RESIDUES 90-100 MUTANT V91L
Descriptor:Tandem repeat of amyloid-related segment of alphaB-crystallin residues 90-100 mutant V91L, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Laganowsky, A., Sawaya, M.R., Cascio, D., Eisenberg, D.
Deposit date:2011-06-15
Release date:2012-03-21
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
3SGS
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AMYLOID-RELATED SEGMENT OF ALPHAB-CRYSTALLIN RESIDUES 95-100
Descriptor:Alpha-crystallin B chain
Authors:Laganowsky, A., Sawaya, M.R., Cascio, D., Eisenberg, D.
Deposit date:2011-06-15
Release date:2012-03-21
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:Atomic view of a toxic amyloid small oligomer.
Science, 335, 2012
3SER
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ZN-MEDIATED POLYMER OF MALTOSE-BINDING PROTEIN K26H/K30H BY SYNTHETIC SYMMETRIZATION
Descriptor:Maltose-binding periplasmic protein, MALTOSE, CHLORIDE ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SES
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CU-MEDIATED DIMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION
Descriptor:Maltose-binding periplasmic protein, MALTOSE, COPPER (II) ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SET
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NI-MEDIATED DIMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION (FORM I)
Descriptor:Maltose-binding periplasmic protein, MALTOSE, NICKEL (II) ION
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEU
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ZN-MEDIATED POLYMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION (FORM III)
Descriptor:Maltose-binding periplasmic protein, MALTOSE, ZINC ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEV
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ZN-MEDIATED TRIMER OF MALTOSE-BINDING PROTEIN E310H/K314H BY SYNTHETIC SYMMETRIZATION
Descriptor:Maltose-binding periplasmic protein, MALTOSE, ZINC ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEW
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ZN-MEDIATED POLYMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION (FORM I)
Descriptor:Maltose-binding periplasmic protein, MALTOSE, ZINC ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEX
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NI-MEDIATED DIMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION (FORM II)
Descriptor:Maltose-binding periplasmic protein, MALTOSE, IODIDE ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SEY
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ZN-MEDIATED POLYMER OF MALTOSE-BINDING PROTEIN A216H/K220H BY SYNTHETIC SYMMETRIZATION (FORM II)
Descriptor:Maltose-binding periplasmic protein, MALTOSE, ZINC ION, ...
Authors:Zhao, M., Soriaga, A.B., Laganowsky, A., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-11
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
3SB5
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ZN-MEDIATED TRIMER OF T4 LYSOZYME R125C/E128C BY SYNTHETIC SYMMETRIZATION
Descriptor:Lysozyme, ZINC ION, CHLORIDE ION, ...
Authors:Laganowsky, A., Soriaga, A.B., Zhao, M., Sawaya, M.R., Cascio, D., Yeates, T.O.
Deposit date:2011-06-03
Release date:2011-09-21
Last modified:2011-11-02
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:An approach to crystallizing proteins by metal-mediated synthetic symmetrization.
Protein Sci., 20, 2011
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