Author results

2FE5
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THE CRYSTAL STRUCTURE OF THE SECOND PDZ DOMAIN OF HUMAN DLG3
分子名称:Presynaptic protein SAP102, SULFATE ION, GLYCEROL
著者Ugochukwu, E., Phillips, C., Schoch, G., Berridge, G., Salah, E., Colebrook, S., Smee, C., Savitsky, P., Bray, J., Elkins, J., Doyle, D., Bunkoczi, G., Debreczeni, J., Turnbull, A., Gorrec, F., von Delft, F., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
登録日2005-12-15
公開日2005-12-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The Crystal Structure of the Second PDZ Domain of Human DLG3
To be Published
2GZV
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THE CYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN PICK1
分子名称:PRKCA-binding protein
著者Debreczeni, J.E., Elkins, J.M., Yang, X., Berridge, G., Bray, J., Colebrook, S., Smee, C., Savitsky, P., Gileadi, O., Turnbull, A., von Delft, F., Doyle, D.A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., Structural Genomics Consortium (SGC)
登録日2006-05-12
公開日2006-07-18
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
6GMC
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1.2 A RESOLUTION STRUCTURE OF HUMAN HYDROXYACID OXIDASE 1 BOUND WITH FMN AND 4-CARBOXY-5-[(4-CHLOROPHENYL)SULFANYL]-1,2,3-THIADIAZOLE
分子名称:Hydroxyacid oxidase 1, 1,2-ETHANEDIOL, FLAVIN MONONUCLEOTIDE, ...
著者MacKinnon, S., Bezerra, G.A., Krojer, T., Smee, C., Arrowsmith, C.H., Edwards, E., Bountra, C., Oppermann, U., Brennan, P.E., Yue, W.W.
登録日2018-05-24
公開日2018-06-13
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate
To Be Published
2J6L
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STRUCTURE OF AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE
分子名称:ALDEHYDE DEHYDROGENASE FAMILY 7 MEMBER A1, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, BROMIDE ION, ...
著者Bunkoczi, G., Guo, K., Debreczeni, J.E., Smee, C., Arrowsmith, C., Edwards, A., Sundstrom, M., Weigelt, J., von Delft, F., Oppermann, U.
登録日2006-09-29
公開日2006-10-12
最終更新日2015-05-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Aldehyde Dehydrogenase 7A1 (Aldh7A1) is a Novel Enzyme Involved in Cellular Defense Against Hyperosmotic Stress.
J.Biol.Chem., 285, 2010
6GMB
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STRUCTURE OF HUMAN HYDROXYACID OXIDASE 1 BOUND WITH FMN AND GLYCOLATE
分子名称:Hydroxyacid oxidase 1, 1,2-ETHANEDIOL, TETRAETHYLENE GLYCOL, ...
著者MacKinnon, S., Bezerra, G.A., Krojer, T., Smee, C., Arrowsmith, C.H., Edwards, E., Bountra, C., Oppermann, U., Brennan, P.E., Yue, W.W., Structural Genomics Consortium (SGC)
登録日2018-05-24
公開日2018-06-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure of human hydroxyacid oxidase 1 bound with FMN and glycolate
To Be Published
2C0C
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STRUCTURE OF THE MGC45594 GENE PRODUCT
分子名称:ZINC BINDING ALCOHOL DEHYDROGENASE, DOMAIN CONTAINING 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Bunkoczi, G., Shafqat, N., Guo, K., Smee, C., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Gileadi, O., von Delft, F., Oppermann, U.
登録日2005-08-30
公開日2005-09-12
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献The Structure of Mgc45594 Gene Product
To be Published
2UXW
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CRYSTAL STRUCTURE OF HUMAN VERY LONG CHAIN ACYL-COA DEHYDROGENASE (ACADVL)
分子名称:VERY-LONG-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, 1,2-ETHANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, ...
著者Pike, A.C.W., Hozjan, V., Smee, C., Berridge, G., Burgess, N., Salah, E., Bunkoczi, G., Uppenberg, J., Ugochukwu, E., von Delft, F., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Oppermann, U.
登録日2007-03-30
公開日2007-05-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Crystal Structure of Human Very Long Chain Acyl- Coa Dehydrogenase (Acadvl)
To be Published
2F8A
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CRYSTAL STRUCTURE OF THE SELENOCYSTEINE TO GLYCINE MUTANT OF HUMAN GLUTATHIONE PEROXIDASE 1
分子名称:Glutathione peroxidase 1, MALONIC ACID
著者Kavanagh, K.L., Johansson, C., Smee, C., Gileadi, O., von Delft, F., Weigelt, J., Sundstrom, M., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2005-12-02
公開日2005-12-13
最終更新日2015-04-29
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of the selenocysteine to glycine mutant of human glutathione peroxidase 1
To be Published
2OZF
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THE CRYSTAL STRUCTURE OF THE 2ND PDZ DOMAIN OF THE HUMAN NHERF-1 (SLC9A3R1)
分子名称:Ezrin-radixin-moesin-binding phosphoprotein 50
著者Phillips, C., Papagrigoriou, E., Gileadi, C., Fedorov, O., Elkins, J., Berridge, G., Turnbull, A.P., Gileadi, O., Schoch, G., Smee, C., Bray, J., Savitsky, P., Uppenberg, J., von Delft, F., Gorrec, F., Umeano, C., Salah, E., Colebrook, S., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-02-26
公開日2007-03-13
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1)
To be Published
2C2N
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STRUCTURE OF HUMAN MITOCHONDRIAL MALONYLTRANSFERASE
分子名称:MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE, SULFATE ION, 3,6,9,12,15-PENTAOXAHEPTADECAN-1-OL, ...
著者Wu, X., Bunkoczi, G., Smee, C., Arrowsmith, C., Sundstrom, M., Weigelt, J., Edwards, A., von Delft, F., Oppermann, U.
登録日2005-09-29
公開日2006-01-18
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural Basis for Different Specificities of Acyltransferases Associated with the Human Cytosolic and Mitochondrial Fatty Acid Synthases.
Chem.Biol., 16, 2009
2C30
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CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 6
分子名称:SERINE/THREONINE-PROTEIN KINASE PAK 6, PHOSPHATE ION, CHLORIDE ION
著者Filippakopoulos, P., Berridge, G., Bray, J., Burgess, N., Colebrook, S., Das, S., Eswaran, J., Gileadi, O., Papagrigoriou, E., Savitsky, P., Smee, C., Turnbull, A., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Knapp, S.
登録日2005-10-02
公開日2006-02-08
最終更新日2019-05-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structures of the P21-Activated Kinases Pak4, Pak5, and Pak6 Reveal Catalytic Domain Plasticity of Active Group II Paks.
Structure, 15, 2007
2C46
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CRYSTAL STRUCTURE OF THE HUMAN RNA GUANYLYLTRANSFERASE AND 5'- PHOSPHATASE
分子名称:MRNA CAPPING ENZYME
著者Debreczeni, J., Johansson, C., Longman, E., Gileadi, O., SavitskySmee, P., Smee, C., Bunkoczi, G., Ugochukwu, E., von Delft, F., Sundstrom, M., Weigelt, J., Arrowsmith, C., Edwards, A., Knapp, S.
登録日2005-10-15
公開日2005-11-01
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of the Human RNA Guanylyltransferase and 5'-Phosphatase
To be Published
2X7H
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CRYSTAL STRUCTURE OF THE HUMAN MGC45594 GENE PRODUCT IN COMPLEX WITH FENOPROFEN
分子名称:ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2, FENOPROFEN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Shafqat, N., Yue, W.W., Ugochukwu, E., Niesen, F., Vollmar, M., Chaikuad, A., Pike, A.C.W., von Delft, F., Smee, C., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2010-02-26
公開日2010-12-08
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of the Human Mgc45594 Gene Product in Complex with Fenoprofen
To be Published
2CJZ
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CRYSTAL STRUCTURE OF THE C472S MUTANT OF HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 (STEP, STRIATUM ENRICHED PHOSPHATASE) IN COMPLEX WITH PHOSPHOTYROSINE
分子名称:HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5, O-PHOSPHOTYROSINE, 1,2-ETHANEDIOL
著者Debreczeni, J.E., Barr, A.J., Eswaran, J., Smee, C., Burgess, N., Gileadi, O., Savitsky, P., Sundstrom, M., Arrowsmith, C., Edwards, A., Weigelt, J., Knapp, S., von Delft, F.
登録日2006-04-10
公開日2006-05-16
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Large-Scale Structural Analysis of the Classical Human Protein Tyrosine Phosphatome.
Cell(Cambridge,Mass.), 136, 2009
2JAM
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CRYSTAL STRUCTURE OF HUMAN CALMODULIN-DEPENDENT PROTEIN KINASE I G
分子名称:CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1G, POLYPEPTIDE, 1,2-ETHANEDIOL, ...
著者Debreczeni, J.E., Bullock, A., Keates, T., Niesen, F.H., Salah, E., Shrestha, L., Smee, C., Sobott, F., Pike, A.C.W., Bunkoczi, G., von Delft, F., Turnbull, A., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Knapp, S.
登録日2006-11-29
公開日2007-03-13
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G
To be Published
2OO1
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CRYSTAL STRUCTURE OF THE BROMO DOMAIN 2 OF HUMAN BROMODOMAIN CONTAINING PROTEIN 3 (BRD3)
分子名称:Bromodomain-containing protein 3, SODIUM ION, 1,2-ETHANEDIOL, ...
著者Filippakopoulos, P., Bullock, A., Papagrigoriou, E., Keates, T., Cooper, C., Smee, C., Ugochukwu, E., Debreczeni, J., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Knapp, S., Structural Genomics Consortium (SGC)
登録日2007-01-25
公開日2007-02-13
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
1ZSY
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THE STRUCTURE OF HUMAN MITOCHONDRIAL 2-ENOYL THIOESTER REDUCTASE (CGI-63)
分子名称:MITOCHONDRIAL 2-ENOYL THIOESTER REDUCTASE, SULFATE ION, GLYCEROL
著者Lukacik, P., Shafqat, N., Kavanagh, K.L., Johansson, C., Smee, C., Edwards, A., Arrowsmith, C., Sundstrom, M., von Delft, F., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2005-05-25
公開日2005-06-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献The structure of human mitochondrial 2-enoyl thioester reductase (CGI-63)
To be Published
2X1H
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CRYSTAL STRUCTURE OF THE HUMAN MGC45594 GENE PRODUCT IN COMPLEX WITH RALOXIFENE
分子名称:ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2, 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Shafqat, N., Yue, W.W., Pike, A.C.W., Niesen, F., Ugochukwu, E., Krojer, T., Chaikuad, A., Smee, C., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2009-12-24
公開日2010-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of the Human Mgc45594 Gene Product in Complex with Raloxifene
To be Published
2FCF
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THE CRYSTAL STRUCTURE OF THE 7TH PDZ DOMAIN OF MPDZ (MUPP-1)
分子名称:Multiple PDZ domain protein
著者Papagrigoriou, E., Berridge, G., Johansson, C., Colebrook, S., Salah, E., Burgess, N., Smee, C., Savitsky, P., Bray, J., Schoch, G., Phillips, C., Gileadi, C., Soundarajan, M., Yang, X., Elkins, J.M., Gorrec, F., Turnbull, A., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2005-12-12
公開日2006-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2BV5
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CRYSTAL STRUCTURE OF THE HUMAN PROTEIN TYROSINE PHOSPHATASE PTPN5 AT 1.8A RESOLUTION
分子名称:TYROSINE-PROTEIN PHOSPHATASE, NON-RECEPTOR TYPE 5, SULFATE ION, ...
著者Debreczeni, J.E., Barr, A.J., Eswaran, J., Smee, C., Burgess, N., Gileadi, O., von Delft, F., Sundstrom, M., Arrowsmith, C., Edwards, A., Knapp, S.
登録日2005-06-22
公開日2005-07-14
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures and inhibitor identification for PTPN5, PTPRR and PTPN7: a family of human MAPK-specific protein tyrosine phosphatases.
Biochem. J., 395, 2006
2C9H
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STRUCTURE OF MITOCHONDRIAL BETA-KETOACYL SYNTHASE
分子名称:MITOCHONDRIAL BETA-KETOACYL SYNTHASE, NICKEL (II) ION
著者Bunkoczi, G., Wu, X., Smee, C., Gileadi, O., Arrowsmith, C., Edwards, A., Sundstrom, M., Weigelt, J., von Delft, F., Oppermann, U.
登録日2005-12-12
公開日2005-12-13
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of Mitochondrial Beta-Ketoacyl Synthase
To be Published
2F57
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CRYSTAL STRUCTURE OF THE HUMAN P21-ACTIVATED KINASE 5
分子名称:Serine/threonine-protein kinase PAK 7, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, N2-[(1R,2S)-2-AMINOCYCLOHEXYL]-N6-(3-CHLOROPHENYL)-9-ETHYL-9H-PURINE-2,6-DIAMINE
著者Eswaran, J., Turnbull, A., Ugochukwu, E., Papagrigoriou, E., Bray, J., Das, S., Savitsky, P., Smee, C., Burgess, N., Fedorov, O., Filippakopoulos, P., von Delft, F., Arrowsmith, C., Weigelt, J., Sundstrom, M., Edwards, A., Knapp, S., Structural Genomics Consortium (SGC)
登録日2005-11-25
公開日2005-12-13
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs.
Structure, 15, 2007
2FNE
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THE CRYSTAL STRUCTURE OF THE 13TH PDZ DOMAIN OF MPDZ
分子名称:Multiple PDZ domain protein
著者Papagrigoriou, E., Berridge, G., Johansson, C., Colebrook, S., Salah, E., Burgess, N., Smee, C., Savitsky, P., Bray, J., Schoch, G., Phillips, C., Gileadi, C., Soundarajan, M., Yang, X., Elkins, J.M., Gorrec, F., Turnbull, A., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-01-11
公開日2006-01-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2FV8
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THE CRYSTAL STRUCTURE OF RHOB IN THE GDP-BOUND STATE
分子名称:Rho-related GTP-binding protein RhoB, GUANOSINE-5'-DIPHOSPHATE
著者Turnbull, A.P., Soundararajan, M., Smee, C., Johansson, C., Schoch, G., Gorrec, F., Bray, J., Papagrigoriou, E., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-01-30
公開日2006-02-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of RhoB in the GDP-bound state
To be Published
2HT9
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THE STRUCTURE OF DIMERIC HUMAN GLUTAREDOXIN 2
分子名称:Glutaredoxin-2, 12-mer peptide, GLUTATHIONE, ...
著者Johansson, C., Smee, C., Kavanagh, K.L., Debreczeni, J., von Delft, F., Gileadi, O., Arrowsmith, C., Weigelt, J., Edwards, A., Sundstrom, M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2006-07-25
公開日2006-08-29
最終更新日2012-12-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria
J.Biol.Chem., 282, 2007
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