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Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based switch motif
Descriptor:	Tyrosine-protein phosphatase non-receptor type 11, immune receptor tyrosine-based switch motif (ITSM)
Authors:	Krausze, J, Sikorska, J, Carlomagno, T.
Deposit date:	2019-05-13
Release date:	2020-02-19
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (2.89 Å)
Cite:	Molecular mechanism of SHP2 activation by PD-1 stimulation. Sci Adv, 6, 2020

Structure of the N-SH2 domain of the human tyrosine-protein phosphatase non-receptor type 11 in complex with the phosphorylated immune receptor tyrosine-based inhibitory motif
Descriptor:	Tyrosine-protein phosphatase non-receptor type 11, immune receptor tyrosine-based inhibitory motif (ITIM)
Authors:	Krausze, J, Sikorska, J, Carlomagno, T.
Deposit date:	2019-05-13
Release date:	2020-02-19
Last modified:	2024-01-24
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Molecular mechanism of SHP2 activation by PD-1 stimulation. Sci Adv, 6, 2020

C-SH2 domain of SHP-2 in complex with phospho-ITSM of PD-1
Descriptor:	ITSM, Tyrosine-protein phosphatase non-receptor type 11
Authors:	Marasco, M.
Deposit date:	2019-03-25
Release date:	2020-02-05
Last modified:	2023-06-14
Method:	SOLUTION NMR
Cite:	Molecular mechanism of SHP2 activation by PD-1 stimulation. Sci Adv, 6, 2020