1WS6
 
 | | The Structure of Thermus thermphillus HB8 hypothetical protein TTHA0928 | | Descriptor: | methyltransferase | | Authors: | Sasaki, C, Sugiura, I, Sugio, S, Tamura, T, Inagaki, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2004-11-01 | | Release date: | 2006-02-07 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The structure of thermus thermphillus HB8 hypothetical protein TTHA0928
TO BE PUBLISHED
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2E1M
 | | Crystal Structure of L-Glutamate Oxidase from Streptomyces sp. X-119-6 | | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, L-glutamate oxidase, PHOSPHATE ION | | Authors: | Sasaki, C, Kashima, A, Sakaguchi, C, Mizuno, H, Arima, J, Kusakabe, H, Tamura, T, Sugio, S, Inagaki, K. | | Deposit date: | 2006-10-26 | | Release date: | 2007-11-13 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural characterization of l-glutamate oxidase from Streptomyces sp. X-119-6
Febs J., 276, 2009
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8YMI
 | | BRD4-BD1 in complex with 2-{[(3S)-1-benzylpyrrolidin-3-yl]methyl}-5-methyl-7-(1-methylpyrazol-3-yl)pyrazolo[4,3-c]pyridin-4-one | | Descriptor: | 1,2-ETHANEDIOL, 2-{[(3S)-1-benzylpyrrolidin-3-yl]methyl}-5-methyl-7-(1-methylpyrazol-3-yl)pyrazolo[4,3-c]pyridin-4-one, Bromodomain-containing protein 4 | | Authors: | Sasaki, C, Miyaguchi, I, Hagihara, S, Ishizawa, K, Endo, J. | | Deposit date: | 2024-03-09 | | Release date: | 2025-03-12 | | Method: | X-RAY DIFFRACTION (1.01 Å) | | Cite: | Discovery of a potent, orally available pyrazolopyridone derivative as a novel selective BET BD1 Inhibitor (Part 2).
To Be Published
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8YMG
 | | BRD4-BD1 in complex with 7-[4-chloro-1-(tetrahydropyran-4-ylmethyl)imidazol-2-yl]-5-methyl-2-{[(2R)-2-methyl-4-methylsulfonyl-piperazin-1-yl]methyl}furo[3,2-c]pyridin-4-one | | Descriptor: | 7-[4-chloro-1-(tetrahydropyran-4-ylmethyl)imidazol-2-yl]-5-methyl-2-{[(2R)-2-methyl-4-methylsulfonyl-piperazin-1-yl]methyl}furo[3,2-c]pyridin-4-one, Bromodomain-containing protein 4 | | Authors: | Sasaki, C, Miyaguchi, I, Hagihara, S, Ishizawa, K, Endo, J. | | Deposit date: | 2024-03-09 | | Release date: | 2025-03-12 | | Method: | X-RAY DIFFRACTION (1.007 Å) | | Cite: | Discovery of a potent, orally available furopyridine derivative as a novel selective BET BD1 Inhibitor (Part 1).
To Be Published
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8YMF
 | | BRD4-BD1 in complex with 7-[2-(cyclopropylmethoxy)phenyl]-5-methyl-2-[(1-methylsulfonyl-4-piperidyl)methyl]pyrazolo[4,3-c]pyridin-4-one | | Descriptor: | 7-[2-(cyclopropylmethoxy)phenyl]-5-methyl-2-[(1-methylsulfonylpiperidin-4-yl)methyl]pyrazolo[4,3-c]pyridin-4-one, Bromodomain-containing protein 4 | | Authors: | Sasaki, C, Miyaguchi, I, Hagihara, S, Ishizawa, K, Endo, J. | | Deposit date: | 2024-03-09 | | Release date: | 2025-03-12 | | Method: | X-RAY DIFFRACTION (1.015 Å) | | Cite: | Discovery of a potent, orally available pyrazolopyridone derivative as a novel selective BET BD1 Inhibitor (Part 2).
To Be Published
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8YMH
 | | BRD4-BD1 in complex with 5-methyl-2-{[(2R)-2-methyl-4-methylsulfonyl-piperazin-1-yl]methyl}-7-(1-methylpyrazol-3-yl)furo[3,2-c]pyridin-4-one | | Descriptor: | 1,2-ETHANEDIOL, 5-methyl-2-{[(2R)-2-methyl-4-methylsulfonyl-piperazin-1-yl]methyl}-7-(1-methylpyrazol-3-yl)furo[3,2-c]pyridin-4-one, Bromodomain-containing protein 4 | | Authors: | Sasaki, C, Miyaguchi, I, Hagihara, S, Ishizawa, K, Endo, J. | | Deposit date: | 2024-03-09 | | Release date: | 2025-03-12 | | Method: | X-RAY DIFFRACTION (1.04 Å) | | Cite: | Discovery of a potent, orally available furopyridine derivative as a novel selective BET BD1 Inhibitor (Part 1).
To Be Published
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8YME
 | | BRD4-BD1 in complex with N-cyclohexyl-1-methyl-6-{[5-methyl-7-(1-methylpyrazol-3-yl)-4-oxo-pyrazolo[4,3-c]pyridin-2-yl]methyl}azepan-1-ium-4-carboxamide 2,2,2-trifluoroacetate | | Descriptor: | (4R,6S)-N-cyclohexyl-1-methyl-6-[[5-methyl-7-(1-methylpyrazol-3-yl)-4-oxidanylidene-pyrazolo[4,3-c]pyridin-2-yl]methyl]azepane-4-carboxamide, 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ... | | Authors: | Sasaki, C, Miyaguchi, I, Hagihara, S, Ishizawa, K, Endo, J. | | Deposit date: | 2024-03-09 | | Release date: | 2025-03-12 | | Method: | X-RAY DIFFRACTION (1.18 Å) | | Cite: | Discovery of a potent, orally available pyrazolopyridone derivative as a novel selective BET BD1 Inhibitor (Part 2).
To Be Published
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1RTU
 | | USTILAGO SPHAEROGENA RIBONUCLEASE U2 | | Descriptor: | RIBONUCLEASE U2, SULFATE ION | | Authors: | Noguchi, S, Satow, Y, Uchida, T, Sasaki, C, Matsuzaki, T. | | Deposit date: | 1995-05-12 | | Release date: | 1996-11-08 | | Last modified: | 2024-11-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of Ustilago sphaerogena ribonuclease U2 at 1.8 A resolution.
Biochemistry, 34, 1995
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1J1B
 | | Binary complex structure of human tau protein kinase I with AMPPNP | | Descriptor: | Glycogen synthase kinase-3 beta, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | Authors: | Aoki, M, Yokota, T, Sugiura, I, Sasaki, C, Hasegawa, T, Okumura, C, Kohno, T, Sugio, S, Matsuzaki, T. | | Deposit date: | 2002-12-03 | | Release date: | 2003-12-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta.
Acta Crystallogr.,Sect.D, 60, 2004
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1J1C
 | | Binary complex structure of human tau protein kinase I with ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Glycogen synthase kinase-3 beta, MAGNESIUM ION | | Authors: | Aoki, M, Yokota, T, Sugiura, I, Sasaki, C, Hasegawa, T, Okumura, C, Kohno, T, Sugio, S, Matsuzaki, T. | | Deposit date: | 2002-12-03 | | Release date: | 2003-12-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta.
Acta Crystallogr.,Sect.D, 60, 2004
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2DY3
 | | Crystal Structure of alanine racemase from Corynebacterium glutamicum | | Descriptor: | Alanine racemase, PYRIDOXAL-5'-PHOSPHATE | | Authors: | Miyaguchi, I, Sasaki, C, Kato, R, Oikawa, T, Sugio, S. | | Deposit date: | 2006-09-05 | | Release date: | 2007-09-11 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structure of Alanine Racemase from Corynebacterium glutamicum at 2.1 A resolution
To be Published
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1J1J
 | | Crystal Structure of human Translin | | Descriptor: | Translin | | Authors: | Sugiura, I, Sasaki, C, Hasegawa, T, Kohno, T, Sugio, S, Moriyama, H, Kasai, M, Matsuzaki, T. | | Deposit date: | 2002-12-06 | | Release date: | 2003-12-06 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of human translin at 2.2 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
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