Author results

3JBW
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF RAG PAIRED COMPLEX (WITH NBD, NO SYMMETRY)
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, 12-RSS signal end forward strand, ...
Authors:Ru, H., Chambers, M.G., Fu, T.-M., Tong, A.B., Liao, M., Wu, H.
Deposit date:2015-10-21
Release date:2015-12-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.631 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3JBX
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF RAG SIGNAL END COMPLEX (C2 SYMMETRY)
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, 5'-D(*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', ...
Authors:Ru, H., Chambers, M.G., Fu, T.-M., Tong, A.B., Liao, M., Wu, H.
Deposit date:2015-10-22
Release date:2015-12-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3JBY
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CRYO-ELECTRON MICROSCOPY STRUCTURE OF RAG PAIRED COMPLEX (C2 SYMMETRY)
Descriptor:V(D)J recombination-activating protein 1, V(D)J recombination-activating protein 2, 5'-D(P*CP*AP*CP*AP*GP*TP*GP*CP*TP*AP*CP*AP*GP*AP*C)-3', ...
Authors:Ru, H., Chambers, M.G., Fu, T.-M., Tong, A.B., Liao, M., Wu, H.
Deposit date:2015-10-22
Release date:2015-12-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures.
Cell(Cambridge,Mass.), 163, 2015
3U3P
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THE S-SAD PHASED CRYSTAL STRUCTURE OF THE ECTO-DOMAIN OF DEATH RECEPTOR 6 (DR6)
Descriptor:Tumor necrosis factor receptor superfamily member 21
Authors:Ru, H., Zhao, L.X., Ding, W., Jiao, L.Y., Shaw, N., Zhang, L.G., Hung, L.W., Matsugaki, N., Wakatsuki, S., Liu, Z.J.
Deposit date:2011-10-06
Release date:2012-05-02
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS
Acta Crystallogr.,Sect.D, 68, 2012
3U3Q
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THE S-SAD PHASED CRYSTAL STRUCTURE OF THE ECTO-DOMAIN OF DEATH RECEPTOR 6 (DR6)
Descriptor:Tumor necrosis factor receptor superfamily member 21
Authors:Ru, H., Zhao, L.X., Ding, W., Jiao, L.Y., Shaw, N., Zhang, L.G., Hung, L.W., Matsugaki, N., Wakatsuki, S., Liu, Z.J.
Deposit date:2011-10-06
Release date:2012-05-02
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS.
Acta Crystallogr.,Sect.D, 68, 2012
3U3S
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THE S-SAD PHASED CRYSTAL STRUCTURE OF THE ECTO-DOMAIN OF DEATH RECEPTOR 6 (DR6)
Descriptor:Tumor necrosis factor receptor superfamily member 21
Authors:Ru, H., Zhao, L.X., Ding, W., Jiao, L.Y., Shaw, N., Zhang, L.G., Hung, L.W., Matsugaki, N., Wakatsuki, S., Liu, Z.J.
Deposit date:2011-10-06
Release date:2012-05-02
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS.
Acta Crystallogr.,Sect.D, 68, 2012
3U3T
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THE S-SAD PHASED CRYSTAL STRUCTURE OF THE ECTO-DOMAIN OF DEATH RECEPTOR 6 (DR6)
Descriptor:Tumor necrosis factor receptor superfamily member 21
Authors:Ru, H., Zhao, L.X., Ding, W., Jiao, L.Y., Shaw, N., Zhang, L.G., Hung, L.W., Matsugaki, N., Wakatsuki, S., Liu, Z.J.
Deposit date:2011-10-06
Release date:2012-05-02
Last modified:2012-07-11
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS
Acta Crystallogr.,Sect.D, 68, 2012
3U3V
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THE S-SAD PHASED CRYSTAL STRUCTURE OF THE ECTO-DOMAIN OF DEATH RECEPTOR 6 (DR6)
Descriptor:Tumor necrosis factor receptor superfamily member 21
Authors:Ru, H., Zhao, L.X., Ding, W., Jiao, L.Y., Shaw, N., Zhang, L.G., Hung, L.W., Matsugaki, N., Wakatsuki, S., Liu, Z.J.
Deposit date:2011-10-06
Release date:2012-05-02
Last modified:2012-07-11
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:S-SAD phasing study of death receptor 6 and its solution conformation revealed by SAXS
Acta Crystallogr.,Sect.D, 68, 2012
4JBJ
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STRUCTURAL MIMICRY FOR FUNCTIONAL ANTAGONISM
Descriptor:Interferon-activable protein 202
Authors:Ru, H., Ni, X., Ma, F., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
Deposit date:2013-02-19
Release date:2013-06-26
Method:X-RAY DIFFRACTION (2.692 Å)
Cite:Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4JBK
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MOLECULAR BASIS FOR ABROGATION OF ACTIVATION OF PRO-INFLAMMATORY CYTOKINES
Descriptor:Interferon-activable protein 202, DNA (5'-D(P*GP*GP*AP*AP*TP*TP*AP*TP*AP*AP*TP*TP*CP*C)-3')
Authors:Ru, H., Ni, X., Crowley, C., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
Deposit date:2013-02-19
Release date:2013-06-26
Method:X-RAY DIFFRACTION (2.963 Å)
Cite:Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
4JBM
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STRUCTURE OF MURINE DNA BINDING PROTEIN BOUND WITH DS DNA
Descriptor:Interferon-inducible protein AIM2, DNA (5'-D(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3')
Authors:Ru, H., Ni, X., Crowley, C., Zhao, L., Ding, W., Hung, L.-W., Shaw, N., Cheng, G., Liu, Z.-J.
Deposit date:2013-02-19
Release date:2013-06-26
Method:X-RAY DIFFRACTION (2.218 Å)
Cite:Structural basis for termination of AIM2-mediated signaling by p202
Cell Res., 23, 2013
6DBI
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CRYO-EM STRUCTURE OF RAG IN COMPLEX WITH 12-RSS AND 23-RSS NICKED DNA INTERMEDIATES
Descriptor:Recombination activating gene 1 - MBP chimera, Recombination activating gene 2, Forward strand of 12-RSS signal end, ...
Authors:Wu, H., Liao, M., Ru, H., Mi, W.
Deposit date:2018-05-03
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (3.36 Å)
Cite:DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBJ
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CRYO-EM STRUCTURE OF RAG IN COMPLEX WITH 12-RSS AND 23-RSS NICKED DNA INTERMEDIATES
Descriptor:Recombination activating gene 1 - MBP chimera, Recombination activating gene 2, Forward stand of RSS signal end, ...
Authors:Wu, H., Liao, M., Ru, H., Mi, W.
Deposit date:2018-05-03
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (2.99 Å)
Cite:DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBL
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CRYO-EM STRUCTURE OF RAG IN COMPLEX WITH 12-RSS AND 23-RSS SUBSTRATE DNAS
Descriptor:Recombination activating gene 1 - MBP chimera, Recombination activating gene 2, Molecule name: Forward strand of 12-RSS substrate DNA, ...
Authors:Wu, H., Liao, M., Ru, H., Mi, W.
Deposit date:2018-05-03
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (5.001 Å)
Cite:DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBO
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CRYO-EM STRUCTURE OF RAG IN COMPLEX WITH 12-RSS AND 23-RSS SUBSTRATE DNAS
Descriptor:Recombination activating gene 1 - MBP chimera, Recombination activating gene 2, Forward strand of substrate RSS DNA, ...
Authors:Wu, H., Liao, M., Ru, H., Mi, W.
Deposit date:2018-05-03
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (4.45 Å)
Cite:DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBQ
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CRYO-EM STRUCTURE OF RAG IN COMPLEX WITH 12-RSS AND 23-RSS SUBSTRATE DNAS
Descriptor:Recombination activating gene 1 - MBP chimera, Recombination activating gene 2, Molecule name: Forward strand of 12-RSS substrate DNA, ...
Authors:Wu, H., Liao, M., Ru, H., Mi, W.
Deposit date:2018-05-03
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (4.22 Å)
Cite:DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBR
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CRYO-EM STRUCTURE OF RAG IN COMPLEX WITH ONE MELTED RSS AND ONE UNMELTED RSS
Descriptor:Recombination activating gene 1 - MBP chimera, Recombination activating gene 2, Forward strand of unmelted RSS substrate DNA, ...
Authors:Wu, H., Liao, M., Ru, H., Mi, W.
Deposit date:2018-05-03
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBT
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CRYO-EM STRUCTURE OF RAG IN COMPLEX WITH 12-RSS AND 23-RSS SUBSTRATE DNAS
Descriptor:Recombination activating gene 1 - MBP chimera, Recombination activating gene 2, Forward strand of 12-RSS substrate DNA, ...
Authors:Wu, H., Liao, M., Ru, H., Mi, W.
Deposit date:2018-05-03
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBU
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CRYO-EM STRUCTURE OF RAG IN COMPLEX WITH 12-RSS AND 23-RSS SUBSTRATE DNAS
Descriptor:Recombination activating gene 1 - MBP chimera, Recombination activating gene 2, Forward strand RSS substrate DNA, ...
Authors:Wu, H., Liao, M., Ru, H., Mi, W.
Deposit date:2018-05-03
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBV
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CRYO-EM STRUCTURE OF RAG IN COMPLEX WITH 12-RSS AND 23-RSS SUBSTRATE DNAS
Descriptor:Recombination activating gene 1 - MBP chimera, Recombination activating gene 2, Forward strand of 12-RSS substrate DNA, ...
Authors:Wu, H., Liao, M., Ru, H., Mi, W.
Deposit date:2018-05-03
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (4.291 Å)
Cite:DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBW
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CRYO-EM STRUCTURE OF RAG IN COMPLEX WITH 12-RSS SUBSTRATE DNA
Descriptor:Recombination activating gene 1 - MBP chimera, Recombination activating gene 2, Forward strand of 12-RSS substrate DNA, ...
Authors:Wu, H., Liao, M., Ru, H., Mi, W.
Deposit date:2018-05-03
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DBX
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CRYO-EM STRUCTURE OF RAG IN COMPLEX WITH 12-RSS SUBSTRATE DNA
Descriptor:Recombination activating gene 1 - MBP chimera, Recombination activating gene 2, Forward strand of 12-RSS substrate DNA, ...
Authors:Wu, H., Liao, M., Ru, H., Mi, W.
Deposit date:2018-05-03
Release date:2018-08-01
Last modified:2018-08-15
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
6DLO
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CRYSTAL STRUCTURE OF LRRK2 WD40 DOMAIN DIMER
Descriptor:Leucine-rich repeat serine/threonine-protein kinase 2
Authors:Zhang, P., Ru, H., Wang, L., Wu, H.
Deposit date:2018-06-02
Release date:2019-01-09
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal structure of the WD40 domain dimer of LRRK2.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6DLP
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CRYSTAL STRUCTURE OF LRRK2 WD40 DOMAIN DIMER
Descriptor:Leucine-rich repeat serine/threonine-protein kinase 2, PLATINUM (II) ION
Authors:Zhang, P., Ru, H., Wang, L., Wu, H.
Deposit date:2018-06-02
Release date:2019-01-09
Last modified:2019-02-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal structure of the WD40 domain dimer of LRRK2.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
4EF4
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CRYSTAL STRUCTURE OF STING CTD COMPLEX WITH C-DI-GMP
Descriptor:Transmembrane protein 173, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION
Authors:Ouyang, S., Ru, H., Shaw, N., Jiang, Y., Niu, F., Zhu, Y., Qiu, W., Li, Y., Liu, Z.-J.
Deposit date:2012-03-29
Release date:2012-05-16
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.147 Å)
Cite:Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
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