Author results

2HMY
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BINARY COMPLEX OF HHAI METHYLTRANSFERASE WITH ADOMET FORMED IN THE PRESENCE OF A SHORT NONPSECIFIC DNA OLIGONUCLEOTIDE
Descriptor:PROTEIN (CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI), S-ADENOSYLMETHIONINE
Authors:O'Gara, M., Zhang, X., Roberts, R.J., Cheng, X.
Deposit date:1999-02-08
Release date:1999-03-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure of a binary complex of HhaI methyltransferase with S-adenosyl-L-methionine formed in the presence of a short non-specific DNA oligonucleotide.
J.Mol.Biol., 287, 1999
3MHT
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TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH UNMODIFIED DNA AND ADOHCY
Descriptor:DNA (5'-D(*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*TP*AP*GP*CP*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE (E.C.2.1.1.73)), ...
Authors:O'Gara, M., Klimasauskas, S., Roberts, R.J., Cheng, X.
Deposit date:1996-07-24
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes.
J.Mol.Biol., 261, 1996
1SA3
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AN ASYMMETRIC COMPLEX OF RESTRICTION ENDONUCLEASE MSPI ON ITS PALINDROMIC DNA RECOGNITION SITE
Descriptor:5'-D(*CP*CP*CP*CP*CP*GP*GP*GP*GP*G)-3', Type II restriction enzyme MspI, SODIUM ION
Authors:Xu, Q.S., Kucera, R.B., Roberts, R.J., Guo, H.C.
Deposit date:2004-02-06
Release date:2004-09-07
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:An Asymmetric Complex of Restriction Endonuclease MspI on Its Palindromic DNA Recognition Site.
STRUCTURE, 12, 2004
1SVU
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STRUCTURE OF THE Q237W MUTANT OF HHAI DNA METHYLTRANSFERASE: AN INSIGHT INTO PROTEIN-PROTEIN INTERACTIONS
Descriptor:Modification methylase HhaI, SULFATE ION, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Dong, A., Zhou, L., Zhang, X., Stickel, S., Roberts, R.J., Cheng, X.
Deposit date:2004-03-30
Release date:2004-06-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structure of the Q237W mutant of HhaI DNA methyltransferase: an insight into protein-protein interactions
Biol.Chem., 385, 2004
1T43
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CRYSTAL STRUCTURE ANALYSIS OF E.COLI PROTEIN (N5)-GLUTAMINE METHYLTRANSFERASE (HEMK)
Descriptor:Protein methyltransferase hemK, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Yang, Z., Shipman, L., Zhang, M., Anton, B.P., Roberts, R.J., Cheng, X.
Deposit date:2004-04-28
Release date:2004-06-29
Last modified:2014-09-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural characterization and comparative phylogenetic analysis of Escherichia coli HemK, a protein (N5)-glutamine methyltransferase.
J.Mol.Biol., 340, 2004
1YFI
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CRYSTAL STRUCTURE OF RESTRICTION ENDONUCLEASE MSPI IN COMPLEX WITH ITS COGNATE DNA IN P212121 SPACE GROUP
Descriptor:5'-D(*CP*CP*CP*CP*CP*GP*GP*GP*GP*G)-3', Type II restriction enzyme MspI
Authors:Xu, Q.S., Kucera, R.B., Roberts, R.J., Guo, H.-C.
Deposit date:2005-01-02
Release date:2006-01-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Two crystal forms of the restriction enzyme MspI-DNA complex show the same novel structure.
Protein Sci., 14, 2005
1YNM
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CRYSTAL STRUCTURE OF RESTRICTION ENDONUCLEASE HINP1I
Descriptor:R.HinP1I restriction endonuclease
Authors:Yang, Z., Horton, J.R., Maunus, R., Wilson, G.G., Roberts, R.J., Cheng, X.
Deposit date:2005-01-24
Release date:2005-05-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of HinP1I endonuclease reveals a striking similarity to the monomeric restriction enzyme MspI
Nucleic Acids Res., 33, 2005
4F0P
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MSPJI RESTRICTION ENDONUCLEASE - P31 FORM
Descriptor:Restriction endonuclease, MAGNESIUM ION
Authors:Horton, J.R., Mabuchi, M., Cohen-Karni, D., Zhang, X., Griggs, R., Samaranayake, M., Roberts, R.J., Zheng, Y., Cheng, X.
Deposit date:2012-05-04
Release date:2012-08-08
Last modified:2012-11-07
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease.
Nucleic Acids Res., 40, 2012
4F0Q
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MSPJI RESTRICTION ENDONUCLEASE - P21 FORM
Descriptor:Restriction endonuclease, MAGNESIUM ION
Authors:Horton, J.R., Mabuchi, M., Cohen-Karni, D., Zhang, X., Griggs, R., Samaranayake, M., Roberts, R.J., Zheng, Y., Cheng, X.
Deposit date:2012-05-04
Release date:2012-08-08
Last modified:2012-11-07
Method:X-RAY DIFFRACTION (2.046 Å)
Cite:Structure and cleavage activity of the tetrameric MspJI DNA modification-dependent restriction endonuclease.
Nucleic Acids Res., 40, 2012
5HR4
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STRUCTURE OF TYPE IIL RESTRICTION-MODIFICATION ENZYME MMEI IN COMPLEX WITH DNA HAS IMPLICATIONS FOR ENGINEERING OF NEW SPECIFICITIES
Descriptor:MmeI, DNA (5'-D(P*TP*AP*TP*CP*CP*GP*AP*CP*AP*TP*AP*AP*C)-3'), DNA (5'-D(P*GP*TP*TP*AP*TP*GP*TP*CP*GP*GP*AP*TP*A)-3'), ...
Authors:Callahan, S.J., Luyten, Y.A., Gupta, Y.K., Wilson, G.G., Roberts, R.J., Morgan, R.D., Aggarwal, A.K.
Deposit date:2016-01-22
Release date:2016-04-27
Method:X-RAY DIFFRACTION (2.5964 Å)
Cite:Structure of Type IIL Restriction-Modification Enzyme MmeI in Complex with DNA Has Implications for Engineering New Specificities.
Plos Biol., 14, 2016
7MHT
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CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
Descriptor:5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', 5'-D(P*CP*CP*AP*TP*GP*AP*GP*CP*TP*GP*AP*C)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
Authors:O'Gara, M., Horton, J.R., Roberts, R.J., Cheng, X.
Deposit date:1998-08-05
Release date:1998-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
8MHT
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CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
Descriptor:5'-D(P*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3', 5'-D(P*CP*CP*AP*TP*GP*UP*GP*CP*TP*GP*AP*C)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
Authors:O'Gara, M., Horton, J.R., Roberts, R.J., Cheng, X.
Deposit date:1998-08-06
Release date:1998-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
9MHT
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CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI/DNA COMPLEX
Descriptor:5'-D(P*CP*CP*AP*TP*GP*CP*GP*CP*TP*GP*AP*C)-3', 5'-D(P*GP*TP*CP*AP*GP*(3DR)P*GP*CP*AP*TP*GP*G)-3', CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
Authors:O'Gara, M., Horton, J.R., Roberts, R.J., Cheng, X.
Deposit date:1998-08-07
Release date:1998-12-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Structures of HhaI methyltransferase complexed with substrates containing mismatches at the target base.
Nat.Struct.Biol., 5, 1998
5MHT
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TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH HEMIMETHYLATED DNA AND ADOHCY
Descriptor:DNA (5'-D(*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*AP*GP*CP*GP*CP*AP*TP*GP*G)-3'), PROTEIN (HHAI METHYLTRANSFERASE), ...
Authors:Cheng, X.
Deposit date:1996-10-22
Release date:1997-07-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A structural basis for the preferential binding of hemimethylated DNA by HhaI DNA methyltransferase.
J.Mol.Biol., 263, 1996
4MHT
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TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH NATIVE DNA AND ADOHCY
Descriptor:DNA (5'-D(*GP*AP*TP*AP*GP*(5CM)P*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*TP*AP*GP*(5CM)P*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE (E.C.2.1.1.73)), ...
Authors:Cheng, X.
Deposit date:1996-07-24
Release date:1997-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Enzymatic C5-cytosine methylation of DNA: mechanistic implications of new crystal structures for HhaL methyltransferase-DNA-AdoHcy complexes.
J.Mol.Biol., 261, 1996
1HMY
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CRYSTAL STRUCTURE OF THE HHAI DNA METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYL-L-METHIONINE
Descriptor:HaeIII METHYLTRANSFERASE, S-ADENOSYLMETHIONINE
Authors:Cheng, X.
Deposit date:1993-08-05
Release date:1993-10-31
Last modified:2012-02-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the HhaI DNA methyltransferase complexed with S-adenosyl-L-methionine.
Cell(Cambridge,Mass.), 74, 1993
1MHT
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COVALENT TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE, DNA AND S-ADENOSYL-L-HOMOCYSTEINE
Descriptor:DNA (5'-D(P*GP*AP*TP*AP*GP*(C36)P*GP*CP*TP*AP*TP*C)-3'), DNA (5'-D(*TP*GP*AP*TP*AP*GP*(C36)P*GP*CP*TP*AP*TP*C)-3'), PROTEIN (HHAI METHYLTRANSFERASE), ...
Authors:Cheng, X.
Deposit date:1994-12-08
Release date:1995-06-03
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:HhaI methyltransferase flips its target base out of the DNA helix.
Cell(Cambridge,Mass.), 76, 1994
2FKC
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CRYSTAL FORM I OF PRE-REACTIVE COMPLEX OF RESTRICTION ENDONUCLEASE HINP1I WITH COGNATE DNA AND CALCIUM ION
Descriptor:5'-D(*CP*CP*AP*GP*CP*GP*CP*TP*GP*G)-3', R.HinP1I restriction endonuclease, CALCIUM ION
Authors:Horton, J.R.
Deposit date:2006-01-04
Release date:2006-02-21
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:DNA nicking by HinP1I endonuclease: bending, base flipping and minor groove expansion.
Nucleic Acids Res., 34, 2006
2FKH
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CRYSTAL FORM II OF PRE-REACTIVE COMPLEX OF RESTRICTION ENDONUCLEASE HINP1I WITH COGNATE DNA AND CALCIUM IONS
Descriptor:5'-D(*CP*CP*AP*GP*CP*GP*CP*TP*GP*G)-3', R.HinP1I Restriction Endonuclease, CALCIUM ION
Authors:Horton, J.R.
Deposit date:2006-01-04
Release date:2006-02-21
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:DNA nicking by HinP1I endonuclease: bending, base flipping and minor groove expansion.
Nucleic Acids Res., 34, 2006
2FL3
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BINARY COMPLEX OF RESTRICTION ENDONUCLEASE HINP1I WITH COGNATE DNA
Descriptor:5'-D(*CP*CP*AP*GP*CP*GP*CP*TP*GP*G)-3', R.HinP1I Restriction Endonuclease
Authors:Horton, J.R.
Deposit date:2006-01-05
Release date:2006-02-21
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:DNA nicking by HinP1I endonuclease: bending, base flipping and minor groove expansion.
Nucleic Acids Res., 34, 2006
2FLC
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POST-REACTIVE COMPLEX OF RESTRICTION ENDONUCLEASE HINP1I WITH NICKED COGNATE DNA AND MAGNESIUM IONS
Descriptor:5'-D(*CP*CP*AP*G)-3', 5'-D(P*CP*GP*CP*TP*GP*G)-3', 5'-D(*CP*CP*AP*GP*CP*GP*CP*TP*GP*G)-3', ...
Authors:Horton, J.R.
Deposit date:2006-01-05
Release date:2006-02-21
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:DNA nicking by HinP1I endonuclease: bending, base flipping and minor groove expansion.
Nucleic Acids Res., 34, 2006
4R28
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MSPJI RESTRICTION ENDONUCLEASE IN COMPLEX WITH 27-MER OLIGONUCLEOTIDE
Descriptor:Restriction endonuclease, DNA (25-MER), DNA (26-MER)
Authors:Horton, J.R., Cheng, X.
Deposit date:2014-08-10
Release date:2014-10-08
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (3.055 Å)
Cite:Modification-dependent restriction endonuclease, MspJI, flips 5-methylcytosine out of the DNA helix.
Nucleic Acids Res., 42, 2014
4LT5
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STRUCTURE OF A NAEGLERIA TET-LIKE DIOXYGENASE IN COMPLEX WITH 5-METHYLCYTOSINE DNA
Descriptor:Naegleria Tet-like dioxygenase, DNA, MANGANESE (II) ION, ...
Authors:Hashimoto, H., Pais, J.E., Zhang, X., Saleh, L., Fu, Z.Q., Dai, N., Correa, I.R., Roberts, R.J., Zheng, Y., Cheng, X.
Deposit date:2013-07-23
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.893 Å)
Cite:Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA.
Nature, 506, 2014
6MHT
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TERNARY STRUCTURE OF HHAI METHYLTRANSFERASE WITH ADOHCY AND DNA CONTAINING 4'-THIO-2'DEOXYCYTIDINE AT THE TARGET
Descriptor:DNA (5'-D(P*CP*CP*AP*TP*GP*(5CM)P*GP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*GP*TP*CP*AP*GP*(4SC)P*GP*CP*AP*TP*GP*G)-3'), CYTOSINE-SPECIFIC METHYLTRANSFERASE HHAI, ...
Authors:Cheng, X.
Deposit date:1998-08-05
Release date:1998-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:DNA containing 4'-thio-2'-deoxycytidine inhibits methylation by HhaI methyltransferase.
Nucleic Acids Res., 25, 1997
4PAR
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THE 5-HYDROXYMETHYLCYTOSINE-SPECIFIC RESTRICTION ENZYME ABASI IN A COMPLEX WITH PRODUCT-LIKE DNA
Descriptor:DNA 18-MER, DNA 14-MER, Uncharacterized protein AbaSI, ...
Authors:Horton, J.R., Cheng, X.
Deposit date:2014-04-09
Release date:2014-06-25
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.89 Å)
Cite:Structure of 5-hydroxymethylcytosine-specific restriction enzyme, AbaSI, in complex with DNA.
Nucleic Acids Res., 42, 2014