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1YWV
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CRYSTAL STRUCTURES OF PROTO-ONCOGENE KINASE PIM1: A TARGET OF ABERRANT SOMATIC HYPERMUTATIONS IN DIFFUSE LARGE CELL LYMPHOMA
Descriptor:Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE
Authors:Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R.
Deposit date:2005-02-18
Release date:2005-04-26
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXS
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CRYSTAL STRUCTURE OF KINASE PIM1 WITH P123M MUTATION
Descriptor:Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE
Authors:Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXT
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CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH AMPPNP
Descriptor:Proto-oncogene serine/threonine-protein kinase Pim-1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXU
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CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH AMP
Descriptor:Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE, ADENOSINE MONOPHOSPHATE
Authors:Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348, 2005
1YXV
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CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH 3,4-DIHYDROXY-1-METHYLQUINOLIN-2(1H)-ONE
Descriptor:Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE, 3,4-DIHYDROXY-1-METHYLQUINOLIN-2(1H)-ONE
Authors:Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348, 2005
1YXX
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CRYSTAL STRUCTURE OF KINASE PIM1 IN COMPLEX WITH (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE
Descriptor:Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE, (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE
Authors:Kumar, A., Mandiyan, V., Suzuki, Y., Zhang, C., Rice, J., Tsai, J., Artis, D.R., Ibrahim, P., Bremer, R.
Deposit date:2005-02-22
Release date:2005-04-26
Last modified:2015-06-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
3MNR
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CRYSTAL STRUCTURE OF BENZAMIDE SNX-1321 BOUND TO HSP90
Descriptor:Heat shock protein HSP 90-alpha, 2-[(3,4,5-trimethoxyphenyl)amino]-4-(2,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-indol-1-yl)benzamide
Authors:Veal, J.M., Fadden, P., Huang, K.H., Rice, J., Hall, S.E., Haytstead, T.A.
Deposit date:2010-04-22
Release date:2010-08-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90.
Chem.Biol., 17, 2010
1STD
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CRYSTAL STRUCTURE OF SCYTALONE DEHYDRATASE: A DISEASE DETERMINANT OF THE RICE PATHOGEN, MAGNAPORTHE GRISEA
Descriptor:SCYTALONE DEHYDRATASE, SULFATE ION, N-[1-(4-BROMOPHENYL)ETHYL]-5-FLUORO SALICYLAMIDE
Authors:Lundqvist, T., Lindqvist, Y.
Deposit date:1994-08-19
Release date:1995-08-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of scytalone dehydratase--a disease determinant of the rice pathogen, Magnaporthe grisea.
Structure, 2, 1994
1IDP
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CRYSTAL STRUCTURE OF SCYTALONE DEHYDRATASE F162A MUTANT IN THE UNLIGATED STATE
Descriptor:SCYTALONE DEHYDRATASE
Authors:Nakasako, M., Motoyama, T., Yamaguchi, I.
Deposit date:2001-04-04
Release date:2003-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystallization of scytalone dehydratase F162A mutant in the unligated state and a preliminary X-ray diffraction study at 37 K
Acta Crystallogr.,Sect.D, 58, 2002
1AR0
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NUCLEAR TRANSPORT FACTOR 2 (NTF2) E42K MUTANT
Descriptor:NUCLEAR TRANSPORT FACTOR 2
Authors:Mccoy, A.J., Stewart, M.J.
Deposit date:1997-08-08
Release date:1997-12-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran.
J.Mol.Biol., 272, 1997
1ASK
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NUCLEAR TRANSPORT FACTOR 2 (NTF2) H66A MUTANT
Descriptor:NUCLEAR TRANSPORT FACTOR 2
Authors:Mccoy, A.J., Stewart, M.J.
Deposit date:1997-08-11
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Nuclear protein import is decreased by engineered mutants of nuclear transport factor 2 (NTF2) that do not bind GDP-Ran.
J.Mol.Biol., 272, 1997
1OUN
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CRYSTAL STRUCTURE OF NUCLEAR TRANSPORT FACTOR 2 (NTF2)
Descriptor:NUCLEAR TRANSPORT FACTOR 2
Authors:Bullock, T.L., Stewart, M.J.
Deposit date:1996-02-21
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The 1.6 angstroms resolution crystal structure of nuclear transport factor 2 (NTF2).
J.Mol.Biol., 260, 1996
3C4C
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B-RAF KINASE IN COMPLEX WITH PLX4720
Descriptor:B-Raf proto-oncogene serine/threonine-protein kinase, N-{3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide
Authors:Zhang, K.Y.J., Wang, W.
Deposit date:2008-01-29
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
Proc.Natl.Acad.Sci.Usa, 105, 2008
3C4E
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PIM-1 KINASE DOMAIN IN COMPLEX WITH 3-AMINOPHENYL-7-AZAINDOLE
Descriptor:Proto-oncogene serine/threonine-protein kinase Pim-1, IMIDAZOLE, N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine
Authors:Zhang, K.Y.J., Wang, W.
Deposit date:2008-01-29
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
Proc.Natl.Acad.Sci.Usa, 105, 2008
3C4F
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FGFR TYROSINE KINASE DOMAIN IN COMPLEX WITH 3-(3-METHOXYBENZYL)-7-AZAINDOLE
Descriptor:Basic fibroblast growth factor receptor 1, 3-(3-methoxybenzyl)-1H-pyrrolo[2,3-b]pyridine
Authors:Zhang, K.Y.J., Wang, W.
Deposit date:2008-01-29
Release date:2008-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity
Proc.Natl.Acad.Sci.Usa, 105, 2008