5UN7
| Structure of the human POT1-TPP1 telomeric complex | Descriptor: | Adrenocortical dysplasia protein homolog, POTASSIUM ION, Protection of telomeres protein 1, ... | Authors: | Rice, C, Doukov, T, Skordalakes, E. | Deposit date: | 2017-01-30 | Release date: | 2017-04-12 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and functional analysis of the human POT1-TPP1 telomeric complex. Nat Commun, 8, 2017
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4JOI
| Crystal structure of the human telomeric Stn1-Ten1 complex | Descriptor: | CST complex subunit STN1, CST complex subunit TEN1 | Authors: | Bryan, C, Rice, C, Harkisheimer, M, Schultz, D, Skordalakes, E. | Deposit date: | 2013-03-18 | Release date: | 2013-05-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of the human telomeric stn1-ten1 capping complex. Plos One, 8, 2013
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5CQG
| Structure of Tribolium telomerase in complex with the highly specific inhibitor BIBR1532 | Descriptor: | 2-{[(2E)-3-(naphthalen-2-yl)but-2-enoyl]amino}benzoic acid, Telomerase reverse transcriptase | Authors: | Bryan, C, Rice, C, Hoffman, H, Harkisheimer, M, Sweeney, M, Skordalakes, E. | Deposit date: | 2015-07-21 | Release date: | 2015-09-09 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis of Telomerase Inhibition by the Highly Specific BIBR1532. Structure, 23, 2015
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1H6Q
| Translationally Controlled Tumor-associated Protein p23fyp from Schizosaccharomyces pombe | Descriptor: | TRANSLATIONALLY CONTROLLED TUMOR PROTEIN | Authors: | Thaw, P, Baxter, N.J, Sedelnikova, S.E, Price, C, Waltho, J.P, Craven, C.J. | Deposit date: | 2001-06-20 | Release date: | 2001-08-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones. Nat. Struct. Biol., 8, 2001
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1H7Y
| Translationally Controlled Tumor-associated Protein p23fyp from Schizosaccharomyces pombe | Descriptor: | TRANSLATIONALLY CONTROLLED TUMOR PROTEIN | Authors: | Thaw, P, Baxter, N.J, Sedelnikova, S.E, Price, C, Waltho, J.P, Craven, C.J. | Deposit date: | 2001-01-19 | Release date: | 2001-08-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones. Nat. Struct. Biol., 8, 2001
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5W2L
| Structure of a central domain of human Ctc1 | Descriptor: | CST complex subunit CTC1, MERCURY (II) ION | Authors: | Rice, C, Skordalakes, E. | Deposit date: | 2017-06-06 | Release date: | 2017-11-29 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes. Nucleic Acids Res., 46, 2018
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7S1O
| Structure of human POT1C | Descriptor: | Protection of telomeres protein 1, ZINC ION | Authors: | Aramburu, T, Skordalakes, E. | Deposit date: | 2021-09-02 | Release date: | 2022-01-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance. Comput Struct Biotechnol J, 20, 2022
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7S1T
| Structure of the human POT1-TPP1 complex | Descriptor: | Adrenocortical dysplasia protein homolog, Protection of telomeres protein 1, ZINC ION | Authors: | Aramburu, T, Skordalakes, E. | Deposit date: | 2021-09-02 | Release date: | 2022-01-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance. Comput Struct Biotechnol J, 20, 2022
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7S1U
| Structure of human POT1C | Descriptor: | Protection of telomeres protein 1, ZINC ION | Authors: | Aramburu, T, Skordalakes, E. | Deposit date: | 2021-09-02 | Release date: | 2022-01-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance. Comput Struct Biotechnol J, 20, 2022
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4JQF
| Structure of the C-terminal domain of human telomeric Stn1 | Descriptor: | CST complex subunit STN1 | Authors: | Bryan, C.F, Rice, C.T, Harkisheimer, M, Schultz, D, Skordalakes, E. | Deposit date: | 2013-03-20 | Release date: | 2013-06-05 | Last modified: | 2013-07-24 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of the human telomeric stn1-ten1 capping complex. Plos One, 8, 2013
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5UGW
| STRUCTURE OF THE HUMAN TELOMERASE THUMB DOMAIN | Descriptor: | GLUTATHIONE, Telomerase reverse transcriptase | Authors: | Skordalakes, E, Hoffman, H. | Deposit date: | 2017-01-10 | Release date: | 2017-02-08 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Bone Marrow Failure Syndromes. J. Biol. Chem., 292, 2017
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7OLI
| Crystal structure of Pab-AGOG in complex with 8-oxoguanosine | Descriptor: | 1,2-ETHANEDIOL, 2'-DEOXY-8-OXOGUANOSINE, N-glycosylase/DNA lyase | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-05-20 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7OLB
| Crystal structure of Pab-AGOG, an 8-oxoguanine DNA glycosylase from Pyrococcus abyssi | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, CITRIC ACID, ... | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-05-19 | Release date: | 2022-06-01 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7OU3
| Crystal structure of Tga-AGOG, an 8-oxoguanine DNA glycosylase from Thermococcus gammatolerans | Descriptor: | CHLORIDE ION, GLYCEROL, N-glycosylase/DNA lyase | Authors: | Coste, F, Confalonieri, F, Castaing, B. | Deposit date: | 2021-06-11 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7OUE
| Crystal structure of a trapped Pab-AGOG/single-standed DNA covalent intermediate | Descriptor: | DNA (5'-D(*TP*TP*TP*(PED)P*TP*TP*TP*CP*T)-3'), N-glycosylase/DNA lyase, PHOSPHATE ION, ... | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-06-11 | Release date: | 2022-06-22 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7P0W
| Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing thymine opposite to lesion) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*TP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*(PED)P*TP*TP*TP*CP*T)-3'), ... | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-06-30 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.12 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7OY7
| Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing cytosine opposite to lesion) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*(PED)P*TP*TP*TP*CP*T)-3'), ... | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-06-23 | Release date: | 2022-07-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7P8L
| Crystal structure of Pyrococcus abyssi 8-oxoguanine DNA glycosylase (PabAGOG) in complex with dsDNA containing cytosine opposite to 8-oxoG | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*CP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*(8OG)P*TP*TP*TP*CP*T)-3'), ... | Authors: | Coste, F, Flament, D, Castaing, B. | Deposit date: | 2021-07-23 | Release date: | 2022-08-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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7P9Z
| Crystal structure of a trapped Pab-AGOG/double-standed DNA covalent intermediate (DNA containing adenine opposite to lesion) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*AP*GP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*(PED)*TP*TP*TP*CP*T)-3'), ... | Authors: | Coste, F, Goffinont, S, Flament, D, Castaing, B. | Deposit date: | 2021-07-28 | Release date: | 2022-08-10 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | Structural and functional determinants of the archaeal 8-oxoguanine-DNA glycosylase AGOG for DNA damage recognition and processing. Nucleic Acids Res., 50, 2022
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4MY2
| Crystal Structure of Norrin in fusion with Maltose Binding Protein | Descriptor: | Maltose-binding periplasmic protein, Norrin fusion protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Ke, J, Jurecky, C, Chen, C, Gu, X, Parker, N, Williams, B.O, Melcher, K, Xu, H.E. | Deposit date: | 2013-09-27 | Release date: | 2013-11-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure and function of Norrin in assembly and activation of a Frizzled 4-Lrp5/6 complex. Genes Dev., 27, 2013
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